Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Risk Factors for Infections After Transplant in a Prospective Cohort Study Including Incompatible Kidney Transplant Recipients
R. Avery,¹ H.-L. Tsai,² C.-Y. Huang,² S. Shoham,¹ D. Ostrander,¹ N. Lu,¹ R. Montgomery,³ K. Marr.¹
¹Infectious Disease, Johns Hopkins, Baltimore, MD; ²Biostatistics and Bioinformatics, Johns Hopkins, Baltimore, MD; ³Transplant Surgery, Johns Hopkins, Baltimore, MD.
Background: Infectious morbidity is a cumulative function of recurrent events. Historically, data collection has depended on time-to-event analyses, variable definitions, and retrospective data. To better…
2015 American Transplant Congress
Hand Assisted Retroperitoneoscopic Donor Nephrectomy in Challenging Cases; Right Sided Donor Nephrectomy With Multiple Renal Arteries
E. Akin,¹ I. Barlas,¹ M. Dayangac,¹ A. Sinangil,² V. Celik,² T. Ecder.²
¹Kidney Transplantation, Istanbul Bilim University Florence Nightengale Hospital, Istanbul, Turkey; ²Nephrology, Istanbul Bilim University Florence Nightengale Hospital, Istanbul, Turkey.
Hand-assisted retroperitoneoscopic (HARP) nephrectomy is a potentially safer approach for the donor where the peritoneum stays intact and tactile sensation remains. The experience with HARP…
2015 American Transplant Congress
The Effect of Changing Candidate Demographics on Living Donor Kidney Transplant Rates
G. Vranic, A. Nishio Lucar, D. Keith.
Medicine, University of Virginia, Charlottesville, VA.
Living donor (LD) rates continue to decline despite a growing list of candidates for renal transplant in the US. While there are many factors driving…
2015 American Transplant Congress
Paired-Donor Exchange Unrelated Living Donor Renal Transplantation With Two Separate Arterial Anastomoses to a Simultaneously Placed Vascular Prosthetic Interposition Graft in an Irradiated Field
D. Haakinson,¹ N. Katariya,¹ A. Singer,¹ A. Mathur,¹ R. Fowl,² S. Money,² W. Stone,² A. Moss,¹ K. Reddy.¹
¹Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ; ²Vascular Surgery, Mayo Clinic Arizona, Phoenix, AZ.
BackgroundLack of suitable sites for arterial anastomoses presents a distinct challenge for renal transplantation in patients with significant peripheral arterial occlusive disease.MethodsWe present a case…
2015 American Transplant Congress
CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures
N. Degauque,^1,2 M. Yap,¹ G. Tilly,^1,3 P. Guerrif,² M. Giral,² S. Brouard,^1,2 Y. Foucher.^2,3
¹INSERM UMR1064, Nantes, France; ²CHU de Nantes, Nantes, France; ³University of Nantes, Nantes, France.
Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…
2015 American Transplant Congress
Living Donor Gifted Lithiasis: Outcomes in Kidney Transplant Recipients
M. Mujtaba, C. Sundaram, M. Yaqub, T. Taber, J. Powelson, S. Doshi, A. Sharfuddin.
Indiana University, Indianapolis.
BACKGROUND: The presence of kidney stones has been a relative contraindication for living donation. The long term outcomes and safety of kidney transplant recipients of…
2015 American Transplant Congress
Single Center Experience of C4d Staining of Kidney Transplant Biopsies
R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.
Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.
Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…
2015 American Transplant Congress
Plasma 4β-Hydroxycholesterol Measurement as a Potential Biomarker for CYP3A5 Activity in Informing Tacrolimus Dosing
T. Elnahhas,^1,2 E. de Jonge,⁴ T. Lee,² B. van Zelst,⁴ J. Popoola,³ R. Ramkhelawon,³ R. van Schaik,⁴ A. Johnston,^1,2 I. MacPhee.³
¹Clinical Pharmacology, Queen Mary University of London, London, United Kingdom; ²Analytical Services International, St.George's University of London, London, United Kingdom; ³Institute of Medical and Biomedical Education-Renal Medicine, St.George's University of London, London, United Kingdom; ⁴Clinical Chemistry, Erasmus MC Rotterdam, Rotterdam, Netherlands.
Background—Recently, 4β-hydroxycholesterol (4β-OHC) has been shown to be an endogenous marker of P450 3A activity in clinical practice (Diczfalusy et al, 2011). 4β-OHC concentration increases…
2015 American Transplant Congress
Conversion from Immediate to Prolonged Release Tacrolimus Did Not Change Intra-Patient Variability in Renal Transplant Patients
T. El-Nahhas,^1,2 M. Moreton,² J. Popoola,³ S. Abat,³ A. Johnston,^1,2 I. MacPhee.³
¹Clinical Pharmacology Department, William Harvey Research Institute, Barts and The London, Queen Mary University of London, London, United Kingdom; ²Analytical Services International, St. George's University of London, London, United Kingdom; ³Institute of Medical and Biomedical Education-Renal Medicine, St. George's University of London, London, United Kingdom.
Background. Tacrolimus has a narrow therapeutic index and is characterized by a large inter- and intra-patient variability (IPV). Variable blood tacrolimus concentrations have been shown…
2015 American Transplant Congress
Impact of Subclinical Rejection (SCR) and Acute Clinical (ACR) in Renal Transplant Recipients
R. Mehta, P. Sood, A. Cherukuri, S. Chen, G. Mour, C. Wu, N. Shah, C. Puttarajappa, P. Randhawa, A. Tevar, S. Hariharan.
University of Pittsburgh Medical Center, Pittsburgh, PA.
The importance of diagnosing subclinical rejection and its short and long term impact remains controversial.We prospectively evaluated 296 patients who had a kidney transplant at…