2022 American Transplant Congress
Assessment of Circulating B Cell Developmental Stages Early After Kidney Transplantation. Preliminary Data from a Single Center
*Purpose: B lymphocytes (BL) is an important immune component in the function of kidney transplants, through antibody production, antigen-presentation to T cells, secretion of cytokines,…2022 American Transplant Congress
BK Polyomavirus Infection is Not Associated with a Meaningful Increase in Donor-Derived Cell-Free DNA
1Warren Alpert Medical School of Brown University, Providence, RI, 2CareDx, Brisbane, CA
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a non-invasive measure of early allograft injury that has been clinically validated as a surveillance tool to detect antibody…2022 American Transplant Congress
Factors Linked with Evaluation to Wait Listing for Referred Patients at the University of Texas Medical Branch’s Main Center and Outreach Clinic – A Step Towards Kidney Transplantation
*Purpose: Numerous factors can be associated with transplant candidates’ placement on the wait list. We herein set forth to assess patient characteristics and factors associated…2022 American Transplant Congress
Evaluation of Genotype Based Clustering Method of Single-Cell RNA-Sequencing Data from Human Kidney Allograft Biopsies
1Weill Cornell Medicine, Doha, Qatar, 2Weill Cornell Medicine, New York, NY
*Purpose: Single-cell RNA sequencing (scRNA-seq) characterizes expression profiles of individual cells, providing novel insights into new cell types or new cell states that were not…2022 American Transplant Congress
Resistance Isn’t Futile: The Independent Effect of Pumping Resistance on Long-Term Kidney Graft Survival
*Purpose: Kidneys are pumped for therapeutic (to mitigate deleterious effects of ischemia), practical (to facilitate transplant scheduling), and prognostic (to assess organ quality) purposes. Yet…2022 American Transplant Congress
Assessing Safety of Using ECMO-Supported Donors in Abdominal Transplantation
*Purpose: Organ donors supported by extracorporeal membrane oxygenation (ECMO) are historically considered high-risk and are judiciously utilized. Here we explore the safety of using organs…2022 American Transplant Congress
CIAT: A New Kidney Exchange Program with Better Options for Highly Sensitized and Long Waiting Patients
*Purpose: A number of alternative, both living and deceased donor kidney transplant programs have been developed for incompatible pairs and difficult to match patients. The…2022 American Transplant Congress
A Machine Learning Approach to Estimating Anticipated Waiting Time and Survival Benefit in Older Kidney Transplant Candidates
1University of Minnesota, Minneapolis, MN, 2U MN, Mpls, MN
*Purpose: Older kidney transplant (ktx) recipients face worse post-transplant survival due to increasing age and more comorbidities. Simultaneously, older ktx candidates are more likely to…2022 American Transplant Congress
One Nuclei at a Time: Decoding Kidney Allograft Fibrosis by Single Nuclei RNA-Sequencing
*Purpose: The biological mechanisms underpinning late graft loss due to chronic allograft dysfunction remain unknown. Single nuclei RNA-sequencing (snRNAseq) of healthy and fibrotic kidney grafts…2022 American Transplant Congress
Safety and Mortality Benefit of Direct Oral Anticoagulants in Kidney Transplant
*Purpose: Direct oral anticoagulants (DOACs) are increasingly used in renal transplant recipients (RTR). We aim to identify bleeding events and all-cause mortality between DOACs and…
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