ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Pharmacokinetics of Mycophenolic Acid (MPA) in Elderly Compared to Young Recipients in the First Year After Renal Transplantation. Data from the NEverOLd Trial

    P. Romano,1 F. Agena,2 P. Ebner,1 A. Triboni,2 F. Ramos,2 N. Galante,2 F. Lemos,2 N. Sumita,1 E. David-Neto.2

    1Division of Central Laboratory, – Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil; 2Renal Transplantation Service, – Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil.

    Elderly (≥60years) recipients are nowadays receiving renal transplants more frequently. The pharmacokinetics studies (PK) of immunosuppressive drugs in healthy volunteers, rarely, if ever, include old…
  • 2015 American Transplant Congress

    Preliminary Results of a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab in a Pediatric Patient Population Undergoing Kidney Transplantation

    D. Halleran,1 S. Schurman, T. Welch, V. Whittaker.

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Pediatric Nephrology, State University New York Upstate Medical University, Syracuse, NY.

    Purpose: We report the outcomes from single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative day…
  • 2015 American Transplant Congress

    Favorable Long-Term Outcome of Late-Onset CMV Disease in D+R- Kidney Transplant Recipients Treated With Universal Prophylaxis

    H. Kaminski,1 L. Couzi,1,2 I. Garrigue,3,4 J. Déchanet-Merville,2 P. Merville.1,2

    1Nephrologie-Transplantation-Dialyse, CHU Bordeaux, Bordeaux, France; 2Unité Mixte de Recherche 5164, Centre National de la Recherche Scientifique, Bordeaux, France; 3Laboratoire de Virologie, CHU Bordeaux, Bordeaux, France; 4Unité Mixte de Recherche 5234, Centre National de la Recherche Scientifique, Bordeaux, France.

    Based on last international guidelines, both universal prophylaxis and preemptive strategies are viable approaches for the prevention of cytomegalovirus (CMV) disease after organ transplantation. Universal…
  • 2015 American Transplant Congress

    Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of Graft Failure and Mortality Among Kidney Transplant Recipients

    P. Clayton,1,2,3 W. Lim,1,4 S. Chadban.1,2,3

    1Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Adelaide, Australia; 2Transplantation, Royal Prince Alfred Hospital, Sydney, Australia; 3Sydney Medical School, University of Sydney, Sydney, Australia; 4Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia.

    Purpose: Graft loss and death are generally late events after kidney transplantation, and trials designed to assess the impact of interventions on these outcomes are…
  • 2015 American Transplant Congress

    Should Only Active Candidates Define the EPTS Top 20% in the New Kidney Allocation System (KAS)?

    D. Stewart,1 A. Kucheryavaya,1 G. Boyle,1 M. Aeder,2 R. Formica.3

    1UNOS, Richmond, VA; 2Univ Hosp Case Med Ctr, Cleveland, OH; 3Yale, New Haven, CT.

    Background: The 20% of kidney candidates with the highest Estimated Post-Transplant Survival (EPTS) receive priority for a high longevity kidney in the Organ Procurement and…
  • 2015 American Transplant Congress

    Immunoglobulin G Donor-Specific Anti-HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated Injury

    D. Viglietti,1,2 C. Bentlejewski,3 J.-P. Duong van Huyen,4,2 D. Vernerey,5,2 O. Aubert,2 J. Verine,1 X. Jouven,2 C. Legendre,4 D. Glotz,1 A. Loupy,2,4 A. Zeevi,3 C. Lefaucheur.1,2

    1Saint-Louis Hospital, Paris, France; 2Paris Translational Research Center for Organ Transplantation - INSERM U970, Paris, France; 3University of Pittsburgh Medical Center, Pittsburgh; 4Necker Hospital, Paris, France; 5CHRU de Besançon, Besançon, France.

    Experimental and clinical data suggest that antibodies have different pathogenicities according to their IgG subclasses. We investigated the association between IgG subclasses of circulating anti-HLA…
  • 2015 American Transplant Congress

    Extended Analysis of Tocilizumab (anti-IL-6R) + Intravenous Immunoglobulin (IVIG) as Desensitization (DES) Agents for Reduction of Donor Specific Antibodies (DSA) in Patients Resistant to DES With IVIG + Rituximab

    A. Vo, J. Choi, I. Kim, J. Kahwaji, A. Peng, R. Villicana, S. Jordan.

    Kidney Transplant, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: IVIG+rituximab is an acceptable approach for DES with good outcomes. Despite this, ∼30% of patients fail DES, thus other approaches are needed. Options include…
  • 2015 American Transplant Congress

    Does Ureteric Stent Avoid Urological Complications After Renal Transplantation? A Retrospective Study of 10 Years Experience

    R. Kato, W. Nahas, K. Yamaçake, H. Kanashiro, R. Falci, A. Bull, I. Antonopoulos, G. Messi, A. Piovesan.

    Divison of Urology, Renal Transplantation Unit, University of São Paulo, São Paulo, SP, Brazil.

    PURPOSE: Urinary leakage and ureteral stenosis are the most common surgical complications after kidney transplantation and are associated with significant morbidity, mortality and prolonged hospital…
  • 2015 American Transplant Congress

    Risk Stratification in Tailoring Induction Therapy in Kidney Transplant Recipients(KTR): Is It Cost-Effective?

    B. Sirandas, A. Carlson, N. Kenyon, C. Truax, L. Smith.

    Transplant, Univ. of Utah, Salt Lake City, UT.

    Intro: Selecting induction therapy based on immunologic risk in KTR has gained popularity but there has yet to be a study evaluating the cost beyond…
  • 2015 American Transplant Congress

    Evaluation of Donor-Specific Antibodies Through 7 Years With Belatacept in BENEFIT and BENEFIT-EXT

    R. Bray,1 H. Gebel,1 R. Townsend,2 U. Meier-Kriesche,2 C. Larsen.1

    1Emory University, Atlanta; 2Bristol-Myers Squibb, Lawrenceville.

    Purpose: The development of donor-specific antibody (DSA) is linked to an increased risk of antibody-mediated rejection and graft failure. The 3 year intent-to-treat results from…
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