Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Survival Benefit of Kidney Transplant Among HIV+ Waitlist Candidates
J. Locke,¹ S. Gustafson,² C. Durand,³ J. Snyder,² B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ S. Mehta,¹ A. Nellore,¹ D. Segev.^2,3
¹University of Alabama, Birmingham, AL; ²Scientific Registry of Transplant Recipients (SRTR), Minneapolis Medical Research Foundation, Minneapolis, MN; ³Johns Hopkins University, Baltimore, MD.
Chronic diseases, such as end-stage renal disease (ESRD), are now the leading causes of death among HIV+ patients. Multiple studies have demonstrated the efficacy of…
2015 American Transplant Congress
Pregnancy Outcomes in Female Kidney Transplant Recipients: Does Ethnicity Have an Influence?
S. Constantinescu,^1,2 L. Coscia,² D. Armenti,² P. Axelrod,¹ M. Ghanta,¹ S. Rao,¹ M. Moritz.^2,3
¹Temple University School of Medicine, Philadelphia; ²National Transplantation Pregnancy Registry, Gift of Life Institute, Philadelphia; ³Lehigh Valley Health Network, Allentown.
The purpose of this study was to analyze pregnancy outcomes in female kidney transplant recipients by ethnicity. Data were collected by the National Transplantation Pregnancy…
2015 American Transplant Congress
Influence of Race on P-Glycoprotein Function in Peripheral Blood Mononuclear Cells
K. Tornatore,¹ H. Minderman,² K. O'Loughlin,² K. Attwood,³ D. Brazeau,⁴ R. Venuto.⁵
¹NYS Center of Excellence in Bioinformatics & Life Science, School of Pharmacy, Buffalo; ²Flow Cytometry Laboratories, Roswell Park Cancer Institute, Buffalo; ³Biostatistics, School of Public Health, Buffalo; ⁴University of New England; School of Pharmacy, Portland, ME; ⁵Medicine, School of Medicine; University at Buffalo, Buffalo, NY.
Purpose: African Americans (AA) renal transplant recipients (RTR) have poorer long term allograft survival compared to Caucasians(C) which may be attributed to racial differences in…
2015 American Transplant Congress
T-Cell Mediated Vascular Rejection Can Be Identified By the Combined Measurement of Five Specific microRNAs in Blood
M. Matz,¹ K. Fabritius,¹ C. Lorkowski,¹ M. Dürr,¹ J. Gaedeke,¹ P. Durek,² J. Grün,² A. Goestemeyer,¹ F. Bachmann,¹ K. Wu,¹ B. Rudolph,¹ U. Weber,¹ C. Haftmann,² N. Unterwalder,³ N. Lachmann,¹ A. Radbruch,² H.-H. Neumayer,¹ M.-F. Mashreghi,² K. Budde.¹
¹University Medicine Charité, Berlin, Germany; ²German Rheumatism Research Centre, Berlin, Germany; ³Labor Berlin GmbH, Berlin, Germany.
MicroRNAs hold important roles in the regulation of gene expression. Their function has been correlated with kidney disease and they might represent a new class…
2015 American Transplant Congress
Immunosuppression With Anti-CD40 mAb and Rapamycin for Islet and Kidney Co-Transplantation in Nonhuman Primates
T. Oura, K. Hotta, J. Lei, J. Markmann, A. Dehnadi, G. Benichou, B. Cosimi, T. Kawai.
Transplant Center, Massachusetts General Hospital, Boston, MA.
Background: For patients with end-stage renal disease secondary to type 1 diabetes mellitus, islet and kidney co-transplantation can be an ideal transplant option. However, a…
2015 American Transplant Congress
Glucose Chemical Exchange Saturation Transfer MRI of Acute Renal Allograft Rejection
D. Kentrup,¹ A. Busch,² H. Pawelski,¹ V. Hoerr,^2,3 S. Reuter.¹
¹Department of Medicine D, University Hospital Münster, Münster, Germany; ²Department of Clinical Radiology, University Hospital Münster, Münster, Germany; ³Institute of Medical Microbiology, Jena University Hospital, Jena, Germany.
Purpose: During acute rejection episodes large amounts of immune cells infiltrate renal grafts, leading to inflammation accompanied by an increased glucose metabolism.Given these circumstances we…
2015 American Transplant Congress
hTERT, BICD1 and Chromosome 18 Polymorphisms Affecting Telomere Length Are Associated With Kidney Transplantation Outcome
L. Domanski,¹ K. Kloda,¹ K. Safranow,² A. Drozd,³ K. Ciechanowski,¹ A. Ciechanowicz.⁴
¹Clinical Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland; ²Department of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland; ³Department of Biochemistry and Human Nutrition, Pomeranian Medical University in Szczecin, Szczecin, Poland; ⁴Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Telomere length (TL) has been analyzed in regard to cell senescence and ageing of animals and humans, including age-related diseases. There have been also attempts…
2015 American Transplant Congress
Low Dose Valganciclovir Is an Effective Prophylaxis Against Cytomegalovirus in High Risk (Donor+/ Recipient-) Kidney Transplants Recipients
S. Fayek,¹ E. Beshears,¹ N. Alvey,² A. Sauer,¹ R. Lieber,¹ O. Olaitan,¹ E. Hollinger,¹ S. Jensik,¹ J. Geyston,² M. Brokhof,² A. Hodowanec,³ D. Simon,³ M. Hertl.¹
¹Surgery/Transplant, Rush University Medical Center, Chicago; ²Pharmacy, Rush University Medical Center, Chicago; ³Medicine/Infectious Diseases, Rush University Medical Center, Chicago.
Introduction: Universal prophylaxis against Cytomegalovirus (CMV) disease is endorsed in high risk seronegative kidney (K) transplant (TX) recipients of organs from seropositive donors (D+/R-) using…
2015 American Transplant Congress
Kidney Transplantation (KTx) With Positive Crossmatch (XM) but No Donor Specific Antibody (DSA)
J. Verbesey, O. Timofeeva, L. Dong, B. Javaid, G. Monica, A. Gilbert, J. Moore, P. Weems, S. Ghasemian, S. Rosen-Bronson, M. Cooper.
MedStar Georgetown Transplant Institute, Washington, DC.
Purpose: Prior to KTx, a XM is performed between the intended recipient and donor. This XM can be positive despite no DSA. It can be…
2015 American Transplant Congress
Outcomes in Kidney Transplant Recipients Over Age of 55 by Donor Source: LD, SCD, ECD
V. Kirchner, K. Gillingham, A. Matas, The Div of Tx and Tx Nephrology.
University of Minnesota, Mpls.
Background: Outcomes in older kidney transplant recipients from SCD and ECD have been studied; however, comparative outcomes between older recipients of LD, SCD and ECD…