ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    The Effect of Rituximab Therapy on Regulatory B Cell and Prevention of Chronic Antibody Mediated Rejection in Kidney Transplantation Recipients

    M. Ikemiyagi, R. Ishii, S. Miyairi, T. Hirai, K. Omoto, K. Tanabe.

    Urology, Tokyo Women's Medical University, Tokyo, Japan.

    We previously reported that a single administration of low dose rituximab (RIT) before kidney transplant reduced the incidence rate of chronic antibody mediated rejection (CAMR)…
  • 2015 American Transplant Congress

    Risk Associated With DCD Kidney Transplantation Varies by Donor Characteristics

    X. Luo, A. Massie, E. Chow, D. Segev.

    Johns Hopkins, Baltimore.

    Studies have shown that comparable kidney graft survival between donors after brain death (DBD) and donors after circulatory death (DCD) overall. However, the differential risk…
  • 2015 American Transplant Congress

    Erythropoietin (EPO) Has Treg Sparing Immunosuppressive Effects On Human Alloreactive T Cells

    C. Purroy, P. Heeger, P. Cravedi.

    Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.

    Extending previous work showing that EPO inhibits alloreactive effector T cell proliferation by uncoupling IL2 receptor signaling (JASN 2014), we tested the effects of EPO…
  • 2015 American Transplant Congress

    Morphometric Age as a Predictor of Survival Following Kidney Transplantation

    M. Terjimanian,1 D. Cron,1 D. Cote,2 J. Augustine,2 K. Noon,2 S. Wang,1 M. Englesbe,1 K. Woodside.2

    1University of Michigan, Ann Arbor, MI; 2Case Western Reserve University, Cleveland, OH.

    INTRODUCTION: Better measures of pre-operative risk stratification are needed in kidney transplantation. Analytic morphomics, which utilizes pre-operative imaging, has been shown to objectively assess mortality…
  • 2015 American Transplant Congress

    The Losing Trifecta: Age ≥70, Deceased Donor Transplant, and Delayed Graft Function

    R. Crew, H. Fernandez, S. Mohan, G. Dube, L. Ratner, R. Sandoval, S. Patel.

    Columbia University, New York.

    INTRO: Patients ≥70 are the fastest growing part of the ESRD population. Although historically patients ≥70 have had acceptable renal transplant outcomes, in our own…
  • 2015 American Transplant Congress

    Constitutively Upregulated Expression of Complement and Matrix Transcripts in Kidney Transplant Recipients Who Develop Acute Rejection

    K. Keslar,1 J. Reid-Adam,4 E. Kwon,4 D. Hricik,5 E. Poggio,2,3 P. Heeger,4 R. Fairchild.1,3

    1Immunology, Cleveland Clinic; 2Nephrology, Cleveland Clinic; 3Glickman Urological Institute and Transplant Center, Cleveland Clinic, Cleveland, OH; 4Icahn School of Medicine, Mount Sinai, New York, NY; 5Nephrology, UH Case Medical Center, Cleveland, OH.

    Identification of kidney transplants at elevated risk of acute rejection (AR) and/or chronic injury prior to loss of kidney function (GFR) could guide therapies to…
  • 2015 American Transplant Congress

    Intrapatient Variability of Tacrolimus Trough Levels and Outpatient Clinic Non-Attendance Rates Predict Poor Renal Allograft Survival

    D. Goodall, M. Willicombe, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    IntroductionNonadherence to immunosuppressive medication post renal transplant is an importnat risk factor for rejection and graft loss. In this study we assess the association between…
  • 2015 American Transplant Congress

    Renal Dysfunction by BK Virus Infection Is Correlated With Activated T Cell Level, Cytokines Level, Gramzymes in Renal Transplantation

    W.-Y. Yin.

    Surgery, Dalin Tzu Chi General Hospital, Chia-I, Taiwan; Surgery, Tzu Chi Univerity, Hualien, Taiwan.

    Purpose:BK virus (BKV) is known to be associated with nephropathy (BKAN). Here, we investigated the relationships between BKV levels, T-cell activation, cytokines and kidney function…
  • 2015 American Transplant Congress

    Maintaining Immunosuppressive Treatment After Early Allograft Nephrectomy Does Not Reduce the Risk of Anti-HLA Allo-Sensitization

    A. Del Bello,1,2 N. Congy-Jolivet,2,3,4 I. Cardeau-Desangles,1 C. Guilbeau-Frugier,2,5 E. Pambrun,1 G. Dörr,1 O. Milioto,6 L. Esposito,1 L. Rostaing,1,2,7 N. Kamar.1,2,7

    1Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Université Paul Sabatier, Faculté de Médecine, Toulouse, France; 3Molecular Immunogenetics Laboratory, EA 3034, Faculté de Médecine Purpan, IFR150, Toulouse, France; 4Department of Immunology, CHU Rangueil, Toulouse, France; 5Department of Pathology, CHU Rangueil, Toulouse, France; 6Nephrology, Clinique Saint-Exupery, Toulouse, France; 7INSERM U1043, IFR–BMT, CHU Purpan, Toulouse, France.

    BackgroundAnti-HLA immunization is greatly increased after early kidney-allograft failure, even if the graft is removed within a few hours post-transplantation. The aim of our study…
  • 2015 American Transplant Congress

    Characteristics of HIV Infected Patients Waitlisted for Kidney Transplantation

    N. Law,1 A. Doyle,1 A. Sharma,1 G. Malat,2 T. Bias,1 K. Ranganna,1 D. Lee.1

    1Department of Medicine, Drexel University, College of Medicine, Philadelphia, PA; 2Department of Surgery, Drexel University, College of Medicine, Philadelphia, PA.

    IntroductionKidney transplantation in HIV+ individuals has been associated with patient and graft survival rates that are comparable to those reported for HIV- populations. Despite this…
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