Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Hypothermic Machine Perfusion Improves Kidney Viability through Amelioration of Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells
Z. Zhong,¹ Z. Liu,¹ Z. Fu,² Y. Zhang,² D. Ko,³ Y. Wang,¹ Q. Ye.^1,2
¹Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, China; ²The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha, Hunan, China; ³Massachusetts General Hospital, Department of Urology, Boston, MA.
Hypothermic machine perfusion (MP) may improve outcome after transplantation from donors after cardiac death (DCD) kidneys, but protective mechanisms of MP remain largely unknown. To…
2015 American Transplant Congress
Treatment of Hepatitis C Virus in Kidney Transplant Recipients With Direct Acting Anti-Viral Agents: Early Results in 12 Cases
A. Sharfuddin,¹ T. Taber,¹ M. Mujtaba,¹ M. Yaqub,¹ D. Mishler,¹ P. Kwo,² R. Vuppalanchi.²
¹Medicine/Nephrology, Indiana University, Indianapolis; ²Medicine/Hepatology, Indiana University, Indianapolis.
Background: Recently approved direct acting antiviral agents (DAA) for treatment of HCV are interferon sparing allowing an attractive treatment option for kidney transplant recipient with…
2015 American Transplant Congress
Validation of Predictive Nomograms for Delayed Graft Function in Kidney Transplant Recipients
L. Chau, O. Famure, J. Kim.
Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Background: Delayed graft function (DGF), defined by the need for dialysis within 7 days after transplantation, impacts short and long term graft outcomes. Predictive nomograms…
2015 American Transplant Congress
Prediction of Long-Term Prognosis of the Kidney Transplantation Using Comorbidity Score
J. Park,¹ E. Bae,¹ S. Kim,² D. Kim,¹ C.-S. Lim,³ K. Joo,¹ Y. Kim,¹ J. Lee.³
¹Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ²Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Korea; ³Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Background: Comorbidity assessment is important to the informed interpretation of kidney allograft outcomes. Weights assigned to comorbidities to predict survival may vary based on the…
2015 American Transplant Congress
Microcirculation Inflammation in Early Surveillance Renal Biopsy in Sensitized Patients Did Not Correlate With Graft Outcome
P. Souza,¹ D. Machado,¹ D. David,¹ G. Bezerra,¹ F. Jota de Paula,¹ H. Rodriges,² W. Nahas,¹ E. David Neto,¹ M. Castro.¹
¹Renal Transplant Unit, HC - FMUSP, S Paulo, SP, Brazil; ²Lab de HLA, InCor, S Paulo, SP, Brazil.
Introduction: Microcirculation inflammation (MI) at 3-month renal biopsies and preformed donor-specific antibodies (DSA) are considered predictors of bad outcome in sensitized patients. Earlier biopsies and…
2015 American Transplant Congress
Longitudinal eGFR Modelling to Understand Rates of eGFR Decline in Renal Transplantation in the United Kingdom
R. Pruthi,¹ A. Casula,¹ R. Hilton,² R. Ravanan,³ P. Roderick,⁴ I. Macphee.⁵
¹UK Renal Registry, Bristol, United Kingdom; ²Guys Hospital, London, United Kingdom; ³Southmead Hospital, Bristol, United Kingdom; ⁴Southampton University, Southampton, United Kingdom; ⁵St Georges Hospital, London, United Kingdom.
Background: The rate of decline in eGFR (slope) has been independently associated with a higher risk of cardiovascular events and all cause mortality in kidney…
2015 American Transplant Congress
Long Term Outcomes With Alemtuzumab Induction Therapy for Deceased and Living Renal Transplant Recipients. A Single Center Experience
P. Vaitla, U. Patel, A. Cruz, S. Guisti, A. Moiz, C.-S. Catherine, A. Cohen, G. Loss, H. Bohorquez, I. Carmody, T. Reichman, D. Bruce, S. Anders, J. Garces.
Ochsner Clinic Foundation, New Orleans, LA.
Background:Antibody induction therapy has been used for induction in up to 80% kidney transplant recipients according to United Network for Organ Sharing. It has been…
2015 American Transplant Congress
Serum Uric Acid Is Associated With Hypertension in Kidney Donors
S. Reule,¹ R. Foley,¹ A. Matas,² H. Ibrahim.¹
¹Department of Medicine, University of Minnesota, Minneapolis, MN; ²Department of Surgery, University of Minnesota, Minneapolis, MN.
Introduction:Uric acid has been linked to the development of hypertension and possibly CKD. Moreover, some preliminary data suggests that lowering uric acid maybe associated with…
2015 American Transplant Congress
Prophylaxis of Post-Renal Transplant Urinary Tract Infection With Fosfomycin Trometamol. A Controlled, Randomized Clinical Trial. (Intermediate Analysis)
J. Arreola-Guerra,¹ L. Morales-Buenrostro,³ M. Arvizu-Hernandez,³ E. Mancilla-Urrea,² P. Maria,² M. Vilatoba-Chapa,¹ J. Alberu,¹ J. Sifuentes-Osornio.¹
¹Transplantation, National Institute of Medical Sciences an Nutrition Salvador Zubirán, Mexico City, Mexico; ²Transplantation, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico; ³Nephrology and Mineral Metabolism, National Institute of Medical Sciences an Nutrition Salvador Zubirán, Mexico City, Mexico.
Background: Urinary tract infection (UTI) is the most frequent infection during post-transplant (pTR) follow-up. Aim: To compare the incidence of UTI during the first 6…
2015 American Transplant Congress
Integrated Clinical-Histological (ICH) Score System for the Evaluation of “Marginal” Donors in Kidney Transplantation
M. Fiorentino,¹ M. Rossini,¹ P. Gallo,¹ G. Castellano,¹ A. Schena,¹ G. Grandaliano,² P. Ditonno,³ M. Bataglia,³ L. Gesualdo.¹
¹Department of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, Italy; ²Department of Medical and Surgical Sciences, Nephrology, Dialysis and Transplantation Unit, University of Foggia, Foggia, Italy; ³Department of Emergency and Organ Transplantation, Andrology, Urology and Renal Transplantation Unit, University of Bari, Bari, Italy.
INTRODUCTION: The organ shortage has led to increase the procurement of kidney from “marginal” donors and to improve the strategies to better evaluate the quality…