2015 American Transplant Congress
Impact of Donor Age on Longterm Outcomes in Asian Kidney Transplant Recipients: A Multicenter Cohort Study
Background The living donor kidney transplantation (LDKT) is well known for best treatment of end-stage renal disease. Recently, kidney transplantation from elderly living donor has…2015 American Transplant Congress
The Association Between Donor & Recipient Gene Variants and Tacrolimus Safety & Efficacy in a Diverse Cohort of Kidney Transplant Recipients
Medical University of South Carolina, Charleston, SC.
Previous studies have associated donor P-glycoprotein (PGP) gene variants (ABCB1) with risk of developing CNI-toxicity, while also establishing recipient CYP3A5*1 and ABCB1 gene variants are…2015 American Transplant Congress
Single Cell Phospho-Protein Analysis Demonstrates That Immunosuppressive Drugs Inhibit MAPK and mTOR Signaling Molecules in Primary Monocytes After Transplantation
Nephrology and Transplantation, Dept. of Internal Medicine, Erasmus MC, Rotterdam, Netherlands.
Monocytes have been identified as key players driving rejection processes. It is therefore surprising that there are almost no data available about the impact of…2015 American Transplant Congress
Emerging Strategies to Screen Kidney Offers Based on the Kidney Donor Profile Index (KDPI)
Background: In the Organ Procurement and Transplantation Network's (OPTN) new kidney allocation system, kidney offers are screened by setting for each candidate a maximum acceptable…2015 American Transplant Congress
Alemtuzumab Induction Is Associated With a Lower Risk of Early Rehospitalization After Kidney Transplant
Early rehospitalizations within the first 30 days (R-30D) are common after kidney transplant. R-30D are costly and associated with an increased risk of graft failure…2015 American Transplant Congress
Comparison of One-Year Outcomes in High Risk Kidney Transplantation: ABO Incompatible and DSA Positive/CDC-AHG Negative
Back ground: Both donor specific anti-HLA antibody (DSA) and anti-ABO are the major barriers in kidney transplantation. We evaluated the outcomes of desensitization protocols in…2015 American Transplant Congress
The Impact of the Arterial Reconstructions On the Living Donor Kidney Graft
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan.
BackgroundProcurement side of living donor kidney is decided according to the kidney function. We procure the kidney with lower function for the remaining donor kidney…2015 American Transplant Congress
Patient Self-Reported Adherence to and Perceptions Towards Immunosuppressive Medications at the Outpatient Renal Transplant Clinic at St. Joseph's Healthcare Hamilton (SJHH)
Objectives To gain insight into the immunosuppressant adherence of patients followed by the Outpatient Renal Transplant Clinic at St. Joseph's Healthcare Hamilton (SJHH) and to…2015 American Transplant Congress
A Primary Cytomegalovirus Infection Post-Transplantation Has a Significant Impact on Circulating T Cells and Renal Allograft Function
Study's purpose: Cytomegalovirus (CMV)-infection may profoundly affect the peripheral T-cell compartment and is associated with T-cell ageing and generation of cytotoxic CD4+CD28null T cells. We…2015 American Transplant Congress
Rapid Effector Function of TEMRA CD8 T Cells in Healthy Volunteers and in Immune-Stimulated Patients Requires Sustained Glycolytic Switch
Background. Contradictory observations have been published regarding the functionality of TEMRA CD8 T cells. TEMRA CD8 have been shown to accumulate with age or chronic…
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