Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Improved Long-Term Graft Survival in Renal Transplant Recipients With Donor Specific Antibodies (DSA) After Mycophenolic Acid Escalation
L. Rebellato,¹ K. Parker,² F. Rana,³ S. Kendrick,⁴ C. Morgan,⁵ C. Haisch,⁵ M. Everly,⁶ R. Harland,⁵ P. Bolin.³
¹Pathology and Laboratory Medicine, East Carolina University, Brody School of Medicine, Greenville, NC; ²Vidant Medical Center, Greenville, NC; ³Internal Medicine, East Carolina University, Brody School of Medicine, Greenville, NC; ⁴Eastern Nephrology Associates, Greenville, NC; ⁵Surgical Immunology and Transplantation, East Carolina University, Brody School of Medicine, Greenville, NC; ⁶Terasaki Foundation, Los Angeles, CA.
Background: DSA formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population indicate DSA formation is a…
2015 American Transplant Congress
Is BK Viral Subtype Distribution of Donor And/Or Recipient Important for Subsequent BK Viral Infection After Living-Donor Transplantation?
A. Schwarz,¹ S. Linnenweber-Held,¹ H. Haller,¹ A. Heim,² C. Schmitt.²
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Virology, Hannover Medical School, Hannover, Germany.
Background: Source and risk factors for developing BK virus (BKV) infection after renal transplantation are unresolved. By genotyping of urine and blood, we looked for…
2015 American Transplant Congress
Interim Safety Experience in Transplant Patients Treated With Belatacept (Nulojix) in the Post-Approval Setting
T. Kou, J. Braga, S. Sibabrata, J. Preston, M. Harler, A. Gomez.
Bristol-Myers Squibb Company, Princeton, NJ.
Purpose: Belatacept is a selective T-cell costimulation blocker indicated for prophylaxis of organ rejection in adult patients receiving a kidney transplant in combination with basiliximab…
2015 American Transplant Congress
Excellent Outcomes With Deceased Donor Kidney Transplants With a Terminal Creatinine >= 3
L. Matsuoka,¹ E. Alicuben,¹ K. Woo,¹ H. Shidban,¹ Y. Qazi,² M. Smogorzewski,² S. Alexopoulos.¹
¹Department of Surgery, USC Keck School of Medicine, Los Angeles, CA; ²Department of Nephrology, USC Keck School of Medicine, Los Angeles, CA.
Purpose: Kidneys from deceased donors with elevated creatinine are frequently discarded due to concerns about poor post-transplant outcomes. In this study we sought to determine…
2015 American Transplant Congress
Recipient Immunity to Murine Cytomegalovirus Influences Natural Killer Cell Responses in Infected Renal Allografts
M. Shimamura,¹ M. Li,¹ B. Chen,² J. George.²
¹Pediatric Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL; ²Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham.
BACKGROUND: Human cytomegalovirus (CMV) is associated epidemiologically with renal allograft loss, but the impact of recipient CMV immunity upon graft survival is unclear. Natural killer…
2015 American Transplant Congress
Post-Transplant Changes in Serum Creatinine and Beta-2 Microglobulin Predict Acute Tubular Necrosis in the Early Post-Transplant Period
P. Liu,¹ A. Djamali,^1,2 D. Kaufman,^2,1 B. Astor.¹
¹Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI; ²Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Purpose: To evaluate the utility of early post-transplant changes in serum creatinine (SCr) and beta-2 microglobulin (B2M) in differentiating acute tubular necrosis (ATN) and other…
2015 American Transplant Congress
Assessing Transplant Attitudes: Understanding Minority Men's Perspectives on the Multifarious Barriers to Organ Donation
B. Hinck, B. Naelitz, B. Jackson, M. Howard, A. Nowacki, C. Modlin.
Glickman Urologic and Kidney Institute - Minority Men's Health Center, Cleveland Clinic, Cleveland, OH.
African-Americans comprise 13% of the US population; yet compose 34% of the kidney transplant waiting list and only 14% of cadaveric donors and 11% of…
2015 American Transplant Congress
High Prevalence of Allograft Rejection in Kidney Recipients With a Mild Increase in Serum Creatinine: Interim Report of the ANIDAR Study
S. De Serres,¹ J. Ho,² J.-F. Cailhier,³ H. Cardinal,³ O. Désy,¹ P. Vallin,¹ S. Béland,¹ I. Côté,¹ I. Houde,¹ R. Noël,¹ I. Lapointe,¹ M. Agharazii.¹
¹Renal Division, CHU de Quebec Hôtel-Dieu, Laval University, Quebec, QC, Canada; ²Sections of Nephrology & Biomedical Proteomics, University of Manitoba, Winnipeg, MB, Canada; ³CHUM, Université de Montréal, Montreal, QC, Canada.
The long-term prognosis of kidney transplants may be impacted by delayed diagnosis of rejection. Guidelines suggest that recipients with an increase of serum creatinine (Scr)…
2015 American Transplant Congress
Body Mass Index (BMI) Mismatch in Deceased Kidney Donation Is an Independent Risk Factor for Graft Failure
O. Staeck,¹ D. Khadzhynov,¹ M. Mahn,² K. Budde,¹ F. Fuller,² F. Halleck.¹
¹Nephrology, Charite Universitaetsmedizin, Berlin, Germany; ²Urology, Charite Universitaetsmedizin, Berlin, Germany.
IntroductionThe influence of this BMI-mismatch in deceased kidney donors and their recipients on graft survival is so far not well characterized.MethodsRetrospective long-term observational study of…
2015 American Transplant Congress
Infections After Alemtuzumab Induction: A Non Issue?
A. Smith, M. John, I. Dortonne, A. Paramesh, M. Killackey, R. Zhang, B. Lee, J. Buell.
Transplant Institute, Tulane University, New Orleans, LA.
Background: Alemtuzumab is a powerful induction agent that depletes multiple lymphocyte cell lines resulting in leukopenia and/or neutropenia with concerns over infectious complications. This study…