2015 American Transplant Congress
The Economic Impact of Nonimmune Complications in Contemporary Kidney Transplantation
The clinical burden and economic impacts of nonimmune complications after kidney transplant (KT) are incompletely defined.We examined United States Renal System Registry Data for Medicare-insured…2015 American Transplant Congress
Assessment of IgG Subclass Significance for Early Graft Rejection and Long-Term Survival in HLA-Antibody Incompatible Renal Transplantation: Multivariate Approach
Donor HLA specific antibodies (DSA) can cause acute rejection and graft lost after renal transplantation. However neither the damaging antibody types, nor their acceptable levels…2015 American Transplant Congress
Loss of RIPK3 and Caspase-8 Enhance Intrinsic Apoptosis in Tubular Epithelial Cell (TEC) Death and Contributes to Kidney Ischemia Reperfusion Injury (IRI)
[Background] Ischemia-reperfusion injury (IRI), a complex limiting factor in organ transplant survival, is related to multiple death pathways. Eliminating the key necroptotic molecule (RIPK3) improves…2015 American Transplant Congress
Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus
BACKGROUND: CMV infection is associated with inferior long-term kidney transplant outcomes. This study compared the incidence of CMV infection/disease in de novo kidney transplant recipients…2015 American Transplant Congress
Impact of Induction Therapy on Outcomes in HIV + Renal Transplant Recipients
Purpose: Kidney transplantation in HIV+ recipients has been complicated by higher than expected acute rejection rates (AR). Induction immunosuppression may or may not impact this…2015 American Transplant Congress
Impact of Cold Ischemic Time (CIT) and Distance Traveled (DT) on Shipped Kidneys in the OPTN/UNOS Kidney Paired Donation (KPD) Pilot Program (PP)
Background: The success of a national KPD program is predicated on excellent early kidney function and graft survival (GS). As other KPD programs have reported…2015 American Transplant Congress
Characteristics and Outcomes of Renal Transplant Recipients With Hemolytic Uremic Syndrome: An OPTN Registry Analysis
Hemolytic uremic syndrome (HUS) accounts for <1% of renal transplants in the US. There is limited data on the characteristics and outcomes of in pediatric…2015 American Transplant Congress
Chimeric Thymus Versus Antigen Presenting Thymus for the Induction of Tolerance: Donor DCs in Vascularized Thymus Grafts Play an Essential Role in the Induction of Tolerance
We have demonstrated that thymus plays an important role in transplantation tolerance in MHC inbred large animals. We have established a technique of isolated vascularized…2015 American Transplant Congress
Impact of Integrase Inhibitor-Based Antiretroviral Regimen on Outcomes in HIV + Renal Transplant Recipients
Beth Israel Deaconess Medical Center, Boston.
Renal transplant in HIV+ patients (pts) is complicated by high rates of acute rejection (AR). Protease inhibitors (PIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs) have…2015 American Transplant Congress
Outcomes of Live Kidney Donors Who Develop End Stage Renal Disease
Kidney donors can develop ESRD after donation, but the outcomes of those who do remain poorly characterized.Methods: Using USRDS and SRTR data, we compared access…
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