ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Conversion from Immediate to Prolonged Release Tacrolimus Did Not Change Intra-Patient Variability in Renal Transplant Patients

    T. El-Nahhas,1,2 M. Moreton,2 J. Popoola,3 S. Abat,3 A. Johnston,1,2 I. MacPhee.3

    1Clinical Pharmacology Department, William Harvey Research Institute, Barts and The London, Queen Mary University of London, London, United Kingdom; 2Analytical Services International, St. George's University of London, London, United Kingdom; 3Institute of Medical and Biomedical Education-Renal Medicine, St. George's University of London, London, United Kingdom.

    Background. Tacrolimus has a narrow therapeutic index and is characterized by a large inter- and intra-patient variability (IPV). Variable blood tacrolimus concentrations have been shown…
  • 2015 American Transplant Congress

    Impact of Subclinical Rejection (SCR) and Acute Clinical (ACR) in Renal Transplant Recipients

    R. Mehta, P. Sood, A. Cherukuri, S. Chen, G. Mour, C. Wu, N. Shah, C. Puttarajappa, P. Randhawa, A. Tevar, S. Hariharan.

    University of Pittsburgh Medical Center, Pittsburgh, PA.

    The importance of diagnosing subclinical rejection and its short and long term impact remains controversial.We prospectively evaluated 296 patients who had a kidney transplant at…
  • 2015 American Transplant Congress

    The Impact of Ureteral Complications After Pediatric Renal Transplantation

    J. Finkelstein,1 J. Pak,1 N. Jain,1 P. Sandoval,2 S. Alam.1

    1Pediatric Urology/Nephrology, Morgan Stanley Children's Hospital, New York, NY; 2Surgery, Columbia University College of Physicians & Surgeons, New York, NY.

    Introduction: The incidence of acute renal allograft rejection has declined with advances in immunosuppression, making the evaluation of other risk factors for graft failure vital.…
  • 2015 American Transplant Congress

    Incidence of Hepatitis B Virus Reactivation in Kidney Transplant Patients Who Received Rituximab Administration

    K. Omoto, M. Okumi, D. Toki, T. Shimizu, H. Ishida, K. Tanabe.

    Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.

    OBJECTIVE:The efficacy of antiviral prophylaxis for rituximab (RIT)-associated hepatitis B virus (HBV) reactivation in patients with lymphoma has been recently reported. However, the immunological effect…
  • 2015 American Transplant Congress

    Transplantation of Neonatal En-Bloc Kidneys: Do They Grow and Are They Subject to Hyperfiltration Injury?

    J. Woloszyn, C. Santhanakrishnan, C. Troppmann, A. DeMattos, B. Gallay, J. McVicar, J. Sageshima, R. Perez.

    UC Davis Transplant Center, Sacramento, CA.

    Importance:Neonatal Intensive Care Unit (NICU) kidney donation is rare but a potentially significant kidney source. Concerns with using these small kidneys include the risk for…
  • 2015 American Transplant Congress

    Matching Strategies in Kidney Paired Donation: A 7-Year Analysis of a Multi-Institutional Registry

    D. Fumo,1,2 L. Reece,2 S. Stepkowski,1 V. Kapoor,1 S. Rees,2 J. Kopke,2 M. Rees.1,2

    1University of Toledo Medical Center, Toledo, OH; 2Alliance for Paired Donation, Maumee, OH.

    Failure to convert computer-identified possible Kidney Paired Donation (KPD) exchanges into transplants has prevented KPD from reaching its full potential. The purpose of this study…
  • 2015 American Transplant Congress

    Serum Proteins Are Significantly Upregulated in Patients With Clinical Antibody-Mediated Rejection

    A. Gareau,1 I. Gibson,2 C. Wiebe,1 J. Ho,1 D. Rush,1 P. Nickerson.1

    1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; 2Pathology, University of Manitoba, Winnipeg, MB, Canada.

    Background: Antibody-mediated rejection (ABMR) is a major pathway associated with late graft loss. Although serum de novo donor-specific HLA antibodies are frequently observed in ABMR,…
  • 2015 American Transplant Congress

    Predicting and Preventing 30-Day Readmission Following Kidney Transplantation: A Single Center Study

    R. Khaim,1 V. Nair.1,2

    1Recanati Miller Transplant Institute, The Mount Sinai Hospital, NY, NY; 2Medicine, Icahn School of Medicine at Mount Sinai, NY, NY.

    Purpose: Readmissions are a major morbidity following kidney transplantation (KT). Prior studies report a 30-day readmission rate of 30%. Limited data exist on risk facotors…
  • 2015 American Transplant Congress

    Stable and Unstable Chimerism During Immunosuppressive Drug Withdrawal in Tolerant Recipients of HLA Matched Combined Kidney and Hematopoietic Cell Transplants

    T. Pham,1 S. Busque,1 J. Scandling,2 J. Shizuru,2 S. Asha,1 S. Strober.2

    1Surgery, Stanford University, Palo Alto, CA; 2Medicine, Stanford University, Palo Alto, CA.

    Our previous studies showed that 75-80% of HLA matched recipients of combined kidney and hematopoietic cell transplants conditioned with total lymphoid irradiation (TLI) and anti-thymocyte…
  • 2015 American Transplant Congress

    Preemptive Deceased Donor Transplant With Kidney Donor Profile Index Scores Greater Than 85 Not Associated With a Survival Benefit

    D. Keith, A. Nishio Lucar, G. Vranic.

    University of Virginia, Charlottesville, VA.

    Preemptively listed candidates for kidney transplant are a unique patient population with regard to marginal quality kidney acceptance as they are not yet dialysis dependent.…
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