ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Maintaining Immunosuppressive Treatment After Early Allograft Nephrectomy Does Not Reduce the Risk of Anti-HLA Allo-Sensitization

    A. Del Bello,1,2 N. Congy-Jolivet,2,3,4 I. Cardeau-Desangles,1 C. Guilbeau-Frugier,2,5 E. Pambrun,1 G. Dörr,1 O. Milioto,6 L. Esposito,1 L. Rostaing,1,2,7 N. Kamar.1,2,7

    1Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France; 2Université Paul Sabatier, Faculté de Médecine, Toulouse, France; 3Molecular Immunogenetics Laboratory, EA 3034, Faculté de Médecine Purpan, IFR150, Toulouse, France; 4Department of Immunology, CHU Rangueil, Toulouse, France; 5Department of Pathology, CHU Rangueil, Toulouse, France; 6Nephrology, Clinique Saint-Exupery, Toulouse, France; 7INSERM U1043, IFR–BMT, CHU Purpan, Toulouse, France.

    BackgroundAnti-HLA immunization is greatly increased after early kidney-allograft failure, even if the graft is removed within a few hours post-transplantation. The aim of our study…
  • 2015 American Transplant Congress

    Characteristics of HIV Infected Patients Waitlisted for Kidney Transplantation

    N. Law,1 A. Doyle,1 A. Sharma,1 G. Malat,2 T. Bias,1 K. Ranganna,1 D. Lee.1

    1Department of Medicine, Drexel University, College of Medicine, Philadelphia, PA; 2Department of Surgery, Drexel University, College of Medicine, Philadelphia, PA.

    IntroductionKidney transplantation in HIV+ individuals has been associated with patient and graft survival rates that are comparable to those reported for HIV- populations. Despite this…
  • 2015 American Transplant Congress

    Angiotensin Receptor Antibody IgG1 Subclass Predicts Accelerated Graft Loss in Those Kidney Transplant Recipients Who Develop Biopsy Proven Transplant Glomerulopathy Irrespective of the Presence Or Absence of Donor Specific Anti HLA Antibodies

    R. Carroll,1 A. Phillippe,2 D. Dragun,2 T. Coates.1

    1Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, SA, Australia; 2Centre for Cardiovascular Research, Charite Hospital, Berlin, Germany.

    We assessed the presence or absence of angiotensin receptor antibodies (ATRab) in all those Kidney Transplant Patients who have had biopsy proven transplant glomerulopathy (TG)…
  • 2015 American Transplant Congress

    Kidney Patients at High Immunological Risk Can Be Safely Transplanted With a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab

    D. Halleran,1 J. Melancon,2 V. Whittaker.1

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Surgery, George Washington University, Washington, DC.

    Purpose: We report the outcomes from our single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative…
  • 2015 American Transplant Congress

    Predicting Obstructive Coronary Artery Disease in Asymptomatic Renal Patients Undergoing Renal Transplantation

    D.-A. Moutzouris, C. Baker, A. Malaweera, M. Willicombe, R. Corbett, N. Duncan, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Almost 50% of asymptomatic patients with End Stage Renal Disease (ESRD) are reported to have significant flow-limiting coronary artery disease (CAD). Our practice involves a…
  • 2015 American Transplant Congress

    Factors Associated With Rehospitalization and High Cost Among Health Plan Members Receiving Kidney Transplants

    E. Lee,1 Y. Zhou,2 B. Suehs,2 B. Franks,1 B. Kassman,1 J. Spalding,1 G. Thal.1

    1Astellas Scientific and Medical Affairs, Northbrook, IL; 2Comprehensive Health Insights, Humana, Louisville, KY.

    PurposeAims were to develop a claims-based algorithm to identify kidney transplant cases and to examine clinical and economic outcomes among health plan members undergoing kidney…
  • 2015 American Transplant Congress

    A Randomized Cross-Over Phase 3b Study of the Pharmacokinetics of Once-Daily Extended Release MeltDose® Tacrolimus (Envarsus® XR) Versus Twice-Daily Tacrolimus in African-Americans (ASERTAA)

    J. Trofe-Clark,1,2 D. Brennan,3 P. West-Thielke,4 M. Milone,5 M. Lim,2 R. Bloom.2

    1Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia; 2Renal Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia; 3Renal Division, Washington University, St. Louis; 4University of Illinois at Chicago, Chicago; 5Penn Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

    The CYP3A5*1 genotype, highly prevalent in African Americans (AA), commonly necessitates higher tacrolimus (tac) dose requirements and may hinder efforts to obtain therapeutic drug levels.…
  • 2015 American Transplant Congress

    The Impact of MYH9 Polymorphic Variant rs5756168 on Kidney Allograft Function

    J. Pazik,1 M. Oldak,2 Z. Lewandowski,3 D. Ozieblo,4 K. Michalska,5 E. Sitarek,1 A. Sadowska,1 M. Nowaczyk,5 T. Grochowiecki,6 J. Malejczyk,4 M. Durlik.1

    1Department of Nephrology and Transplantation Medicine, Medical University of Warsaw, Warsaw, Poland; 2Institute of Physiology and Pathology of Hearing, Warsaw, Poland; 3Department of Epidemiology, Medical University of Warsaw, Warsaw, Poland; 4Department of Histology and Embryology, Medical University of Warsaw, Warsaw, Poland; 5Department of Clinical Immunology, Medical University of Warsaw, Warsaw, Poland; 6General, Vascular and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland.

    The MYH9 gene was identified as a susceptibility locus associated with diminished filtration rate in the course of chronic nephropathies: primary focal segmental glomerulosclerosis (FSGS),…
  • 2015 American Transplant Congress

    Renal Resistance Measured During Pulsatile Perfusion and Long-Term Kidney Transplant Outcomes

    S. Sandal, R. Sapir-Pichhadze, M. Cantarovich, S. Paraskevas.

    McGill University Health Center, Montreal, QC, Canada.

    Background: Pulsatile perfusion (PP) has been shown to reduce the incidence of delayed graft function (DGF) and increase short- and long-term kidney transplant (KT) survival.…
  • 2015 American Transplant Congress

    Living Kidney Donation in the Elderly: The United Kingdom Experience

    Z. Ahmed,1 R. Tamburrini,1 L. Pankhurst,2 N. Kessaris,1 N. Mamode.1

    1Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; 2Department of Clinicsl Trials and Statistics, NHS Blood and Transplant, Bristol, United Kingdom.

    Introduction: The increasing demand for organs has led many institutions to accept elderly patients onto their living donor programmes. However no large UK based datasets…
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