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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Protecting Older Patients from Dialysis: The Survival Benefit of Preemptive Transplant With High KDPI Allografts

    C. Jay,1 K. Washburn,1 P. Dean,2 R. Helmick,2 M. Stegall.2

    1Transplant Center, University of Texas Health Science Center, San Antonio, TX; 2Department of Surgery, Division of Transplantation, Mayo Clinic, Rochester, MN.

    BACKGROUND: Mortality on dialysis remain markedly elevated in patients over 60 years old. Preemptive kidney transplantation (PreKT) represents a means of avoiding the risks of…
  • 2015 American Transplant Congress

    Incidence of CMV Viremia in Obese and Morbidly Obese Kidney Transplants Under a Low Dose Valganciclovir Prophylaxis Protocol

    J. Thielke,1 P. West-Thielke,2 E. Benedetti.2

    1Pharmacy Practice, Univ of IL-Chicago, Chicago, IL; 2Surgery, Univ of IL-Chicago, Chicago, IL.

    Background: The rate of Cytomegalovirus infections in kidney transplant recipients drastically diminished with the advent of oral ganciclovir and subsequently valganciclovir. However it continues to…
  • 2015 American Transplant Congress

    Effect of Everolimus on Left Ventricular Hypertrophy in De Novo Kidney Transplant Recipients: 12-Month Results from the ELEVATE Study

    M. van der Giet,1 H. Holdaas,1 J. de Fijter,1 A. Speziale,2 C. Escrig,2 G. Junge,2 Z. Wang,3 J. Cruzado.1

    1For the ELEVATE Study, Berlin, Germany; 2Novartis, Basel, Switzerland; 3Novartis Corporation, East Hannover, NJ.

    Background: Left ventricular hypertrophy (LVH) is common in kidney transplant recipients (KTxR) and has shown to be a risk factor for death and heart failure…
  • 2015 American Transplant Congress

    Everolimus Conversion to Treat BK Virus Infection in Kidney Transplant Recipients

    D. Wojciechowski, A. Webber, S. Chandran, F. Vincenti.

    UCSF, San Francisco.

    IntroductionmTORi's reduce BKV large T antigen expression in vitro and are associated with lower rates of BKV infection in clinical studies.MethodsPilot single center, randomized, open-label…
  • 2015 American Transplant Congress

    The Occurrence of v- Lesions Is Not Associated With Decreased Graft Survival

    P. Halloran, I. Salazar, M. Lopez, J. Chang.

    ATAGC, Edmonton, Canada.

    Intimal arteritis (v-lesions) in kidney transplant biopsies has been believed to have major prognostic and diagnostic significance. We assessed the relationship of v-lesions to prognosis…
  • 2015 American Transplant Congress

    CD28-Directed Therapy Prolongs Survival in a Non-Human Primate Kidney Transplant Model

    L. Higginbotham,1 D. Mathews,1 C. Breeden,1 W. Wakwe,1 C. Larsen,1 S. Nadler,2 A. Adams.1

    1Emory Transplant Center, Emory University School of Medicine, Atlanta; 2Bristol-Myers Squibb, Princeton.

    Introduction. Costimulation blockade using belatacept has the potential to improve long-term renal function and reduce cardiovascular risk by avoiding calcineurin inhibitors, yet higher rates and…
  • 2015 American Transplant Congress

    Depression of Complement Regulatory Factors in Human and Rat Renal Grafts in Association With Progress of Acute Cellular Rejection

    K. Yamanaka,1 T. Kato,1 Y. Kakuta,1 T. Abe,1 R. Imamura,1 A. Maeda,2 S. Miyagawa,2 N. Nonomura.1

    1Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; 2Organ Transplantation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

    Introduction and ObjectiveIt is commonly known that complements play important roles in antibody mediated rejection in renal transplantation. However, the association of complements with progression…
  • 2015 American Transplant Congress

    Histologic Findings in Pre-transplant AT1Rab + ve Patients Point to an Increase in Sub-Intimal Fibrosis During Acute Rejection and in 12 mo. Protocol Renal Graft Biopsies

    A. González-Almada, J. Arreola-Guerra, E. Cuevas, M. Vilatoba, A. Contreras, A. Sanchez-Cedillo, J. Alberu, N. Uribe-Uribe.

    1Transplantation, 1aNephrology-Mineral Metabolism, 1bPathology, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.

    Previous reports have described an increase in arteritis during acute rejection (AR) in angiotensin II type 1 receptor antibody (AT1Rab) positive (ve+) kidney transplant recipients…
  • 2015 American Transplant Congress

    Impact of Early Urinary Tract Infections on Renal Graft Function

    J. Rago, L. Bowman, D. Brennan, J. Hagopain, T. Horwedel.

    Barnes Jewish Hospital, St Louis, MO.

    Purpose: Describe the incidence of early urinary tract infections (UTI) after renal transplantation at a large academic transplant center. Evaluate the impact of early UTIs…
  • 2015 American Transplant Congress

    De Novo Donor-Specific HLA Antibodies After Kidney Transplantation Are Associated With Donation After Circulatory Death and HLA-DQ Mismatch

    G. Dreyer,1 D. Roelen,2 S. Brand-Schaaf,2 O. Dekkers,3 M. Reinders,1 F. Claas,2 J. de Fijter.1

    1Nephrologie, LUMC, Leiden, Netherlands; 2Immunohaematology and Blood Transfusion, LUMC, Leiden, Netherlands; 3Clinical Epidemiology, Aarhus Medical Center, Aarhus C, Denmark.

    Introduction: De novo donor-specific HLA-antibodies (dnDSA) have been associated with rejection and inferior kidney graft survival. The purpose of this study was to investigate the…
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