2015 American Transplant Congress
Urinary CXCL10 Independently Improves the Noninvasive Diagnosis of Antibody-Mediated Kidney Allograft Rejection
The urinary levels of CXCL9 and CXCL10 can noninvasively diagnose T cell-mediated rejection (TCMR) of renal allografts. Their performance as diagnostic/prognostic markers of antibody-mediated rejection…2015 American Transplant Congress
Patient and Process-Level Factors Associated With Kidney Transplant Readmissions
Readmissions following kidney transplantation (KTX) are common, with complex etiologies. There is a lack of research exploring the potential of optimizing post-transplant processes to reduce…2015 American Transplant Congress
The Effect of Rituximab Therapy on Regulatory B Cell and Prevention of Chronic Antibody Mediated Rejection in Kidney Transplantation Recipients
Urology, Tokyo Women's Medical University, Tokyo, Japan.
We previously reported that a single administration of low dose rituximab (RIT) before kidney transplant reduced the incidence rate of chronic antibody mediated rejection (CAMR)…2015 American Transplant Congress
Risk Associated With DCD Kidney Transplantation Varies by Donor Characteristics
Studies have shown that comparable kidney graft survival between donors after brain death (DBD) and donors after circulatory death (DCD) overall. However, the differential risk…2015 American Transplant Congress
Erythropoietin (EPO) Has Treg Sparing Immunosuppressive Effects On Human Alloreactive T Cells
Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Extending previous work showing that EPO inhibits alloreactive effector T cell proliferation by uncoupling IL2 receptor signaling (JASN 2014), we tested the effects of EPO…2015 American Transplant Congress
Morphometric Age as a Predictor of Survival Following Kidney Transplantation
1University of Michigan, Ann Arbor, MI; 2Case Western Reserve University, Cleveland, OH.
INTRODUCTION: Better measures of pre-operative risk stratification are needed in kidney transplantation. Analytic morphomics, which utilizes pre-operative imaging, has been shown to objectively assess mortality…2015 American Transplant Congress
The Losing Trifecta: Age ≥70, Deceased Donor Transplant, and Delayed Graft Function
Columbia University, New York.
INTRO: Patients ≥70 are the fastest growing part of the ESRD population. Although historically patients ≥70 have had acceptable renal transplant outcomes, in our own…2015 American Transplant Congress
Constitutively Upregulated Expression of Complement and Matrix Transcripts in Kidney Transplant Recipients Who Develop Acute Rejection
Identification of kidney transplants at elevated risk of acute rejection (AR) and/or chronic injury prior to loss of kidney function (GFR) could guide therapies to…2015 American Transplant Congress
Intrapatient Variability of Tacrolimus Trough Levels and Outpatient Clinic Non-Attendance Rates Predict Poor Renal Allograft Survival
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
IntroductionNonadherence to immunosuppressive medication post renal transplant is an importnat risk factor for rejection and graft loss. In this study we assess the association between…2015 American Transplant Congress
Renal Dysfunction by BK Virus Infection Is Correlated With Activated T Cell Level, Cytokines Level, Gramzymes in Renal Transplantation
Purpose:BK virus (BKV) is known to be associated with nephropathy (BKAN). Here, we investigated the relationships between BKV levels, T-cell activation, cytokines and kidney function…
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