ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Risk Factors for Acute Cellular Rejection for Pediatric Kidney Transplant Recipients

    D. Cote,1 I. Bobanga,1 B. Vogt,2 K. Dell,2 R. Cunningham III,2 K. Noon,1 V. Humphreville,1 E. Sanchez,1 J. Schulak,1 K. Woodside.1

    1Department of Surgery, Case Western Reserve University & University Hospitals, Cleveland, OH; 2Department of Pediatrics, Case Western Reserve University & University Hospitals, Cleveland, OH.

    Background: Acute cellular rejection (ACR) potentially shortens the life of a kidney allograft. We sought to determine risk factors associated with the development of ACR…
  • 2015 American Transplant Congress

    The Explore Transplant Program in GA: Is Historical Access to Transplantation Associated With Kidney Transplant Knowledge and Preparedness to Educate ERSD Patients?

    J. Gander,1 C. Isenhour,1 L. McPherson,1 M. Basu,1 B. Tao,1 K. Smtih,1 S. Pastan,1 A. Waterman,2 R. Patzer.1

    1Emory University, Atlanta; 2University of California, Los Angeles.

    IntroductionDialysis facilities play a key role in educating end stage renal disease patients on kidney transplantation (KTx). We aimed to investigate the association between historical…
  • 2015 American Transplant Congress

    Long-term Patient and Graft Survival After Kidney Transplantation in Recipients With Hepatitis C Virus Infection

    N.-Y. Heo, P. Udompap, A. Mannalithara, W. Kim.

    Division of Gastroenterology and Hepatology, Stanford University, Stanford.

    Background: The prevalence of hepatitis C virus (HCV) infection among kidney transplant (KTx) recipients is higher than that in the general population. With the advent…
  • 2015 American Transplant Congress

    Donor-Specific Alloantibody After Positive Crossmatch Kidney Transplantation With Eculizumab (EC): Correlation With Transplant Glomerulopathy and Graft Failure

    C. Schinstock,1 F. Cosio,1 L. Cornell,1 M. Gandhi,1 M. Everly,2 M. Stegall.1

    1Mayo Clinic, Rochester, MN; 2Paul Terasaki Foundation, Los Angeles, CA.

    Introduction. EC (C5 blockade) reduces the incidence of early clinical acute antibody mediated rejection (AMR) after +XMKTx, but does not prevent chronic AMR. We examined…
  • 2015 American Transplant Congress

    Multicenter Validation of a Molecular Diagnostic for Antibody-Mediated Rejection in Formalin-Fixed Paraffin-Embedded Human Renal Allograft Biopsies

    B. Adam,1 B. Afzali,1 N. Shah,1 K. Dominy,2 R. Gill,1 L. Hidalgo,1 P. Campbell,1 C. Roufosse,2 M. Mengel,1 B. Sis.1

    1University of Alberta, Edmonton, Canada; 2Imperial College, London, United Kingdom.

    Background: In 2013, the Banff classification adopted molecular diagnostics as an adjunct for the diagnosis of antibody-mediated rejection (ABMR) in renal allografts. The NanoString gene…
  • 2015 American Transplant Congress

    CHBP Suppresses Acute Rejection by Inhibition Maturation of Dendritic Cells though Jak-2/STAT3/SOCS1 Signal in Rat Kidney Transplantation

    C. Yang,1 Y. Zhang,1 J. Wang,1 L. Li,1 L. Wang,2 M. Xu,1 Y. Long,3 R. Rong,1 T. Zhu.1

    1Urology, Zhongshan Hospital, Fudan University, Shanghai, China; 2Biomedical Research Center, Zhongshan Hospital, Fudan University, Shanghai, China; 3CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

    Background. Renal acute rejection (AR) affects both allografts and recipients survival. We recently synthesized a novel proteolysis-resistant cyclic helix B peptide (CHBP), which exerts promising…
  • 2015 American Transplant Congress

    Targeting Complement Pathways During Ischemia and Reperfusion: Implications for the Prevention of Delayed Graft Function

    Z. Yu,1 S. Qi,2 M. Lasaro,1 K. Bouchard,1 C. Dow,1 K. Moore,1 Z. Wu,2 A. Barama,2 J. Xu,2 K. Johnson,1 A. Marozsan,1 Y. Wang.1

    1Pre-Clinical Sciences, Alexion Pharmaceutical Inc., Cheshire, CT; 2Department of Surgery, Hôpital Notre Dame and Université de Montréal, Montréal, QC, Canada.

    Complement system plays a critical role in ischemia-reperfusion injury (IRI), and contributes to DGF. The aim of this study was to evaluate the effects of…
  • 2015 American Transplant Congress

    Deceased Donor Kidney Transplantation Without Calcineurin Inhibitors or Steroids

    A. Kirk,1,2 A. Guasch,1 S. Mead,1 A. Ghali,1 A. Mehta,1 H. Gebel,1 R. Bray,1 C. Larsen,1 T. Pearson.1

    1Transplant Center, Emory University, Atlanta, GA; 2Surgery, Duke University, Durham, NC.

    Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative delivered by monthly intravenous infusion, but…
  • 2015 American Transplant Congress

    The Role of Hemodialysis Social Networks in Transplantation: Five Year Follow Up of an Urban Hemodialysis Cohort

    A. Pai, A. Gillespie.

    Nephrology, Hypertension, and Kidney Transplantation, Temple University, Philadelphia, PA.

    Background: Racial and socioeconomic disparities are well known barriers to kidney transplantation (KT), especially among minority populations. Emerging evidence suggests social networks exist within hemodialysis…
  • 2015 American Transplant Congress

    Implications of Living Donor Kidney Histology, Volume and Function on Post-Donation GFR

    Z. Zaky,1 B. Lankowsky,2 S. Shah,1 L. Herlitz,1 A. Chiesa-Vottero,1 K. Wallenfelsz,1 A. Caplin,1 D. Goldfarb,1 S. Flechner,1 J. Schold,1 E. Poggio.1

    1Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH; 2CWRU School of Medicine, Cleveland, OH.

    Living kidney donor transplantation is the best modality for treating ESRD as it confers excellent outcomes to patients and it is safe for donors. Postdonation…
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