2015 American Transplant Congress
Multicenter Validation of a Molecular Diagnostic for Antibody-Mediated Rejection in Formalin-Fixed Paraffin-Embedded Human Renal Allograft Biopsies
1University of Alberta, Edmonton, Canada; 2Imperial College, London, United Kingdom.
Background: In 2013, the Banff classification adopted molecular diagnostics as an adjunct for the diagnosis of antibody-mediated rejection (ABMR) in renal allografts. The NanoString gene…2015 American Transplant Congress
CHBP Suppresses Acute Rejection by Inhibition Maturation of Dendritic Cells though Jak-2/STAT3/SOCS1 Signal in Rat Kidney Transplantation
Background. Renal acute rejection (AR) affects both allografts and recipients survival. We recently synthesized a novel proteolysis-resistant cyclic helix B peptide (CHBP), which exerts promising…2015 American Transplant Congress
Targeting Complement Pathways During Ischemia and Reperfusion: Implications for the Prevention of Delayed Graft Function
Complement system plays a critical role in ischemia-reperfusion injury (IRI), and contributes to DGF. The aim of this study was to evaluate the effects of…2015 American Transplant Congress
Deceased Donor Kidney Transplantation Without Calcineurin Inhibitors or Steroids
1Transplant Center, Emory University, Atlanta, GA; 2Surgery, Duke University, Durham, NC.
Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative delivered by monthly intravenous infusion, but…2015 American Transplant Congress
The Role of Hemodialysis Social Networks in Transplantation: Five Year Follow Up of an Urban Hemodialysis Cohort
Nephrology, Hypertension, and Kidney Transplantation, Temple University, Philadelphia, PA.
Background: Racial and socioeconomic disparities are well known barriers to kidney transplantation (KT), especially among minority populations. Emerging evidence suggests social networks exist within hemodialysis…2015 American Transplant Congress
Implications of Living Donor Kidney Histology, Volume and Function on Post-Donation GFR
Living kidney donor transplantation is the best modality for treating ESRD as it confers excellent outcomes to patients and it is safe for donors. Postdonation…2015 American Transplant Congress
Successful Management of Post Transplant Focal Segmental Glomerulosclerosis With Plasma Exchange and Rituximab
Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with renal allograft loss. Currently, optimal treatment remains controversial. We propose a management protocol that includes treatment…2015 American Transplant Congress
Post-Transplant Lymphoproliferative Disorders Following Alemtuzumab Induction in Kidney Transplantation
Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, England, United Kingdom.
Post-Transplant Lymphoproliferative Disorder (PLTD) is a well-recognised serious complication in renal transplant recipients. Induction with lymphocyte depleting agents such as thymoglobulin has been associated with…2015 American Transplant Congress
Patient and Graft Outcomes Following 3rd, 4th and 5th Renal Transplants – A Single Centre Comparative Study
Guy's and St Thomas' Hospital - NHS Foundation Trust, London, United Kingdom.
Introduction: For patients who have lost their first renal graft, a second kidney transplant is widely accepted as the next best therapeutic option (due to…2015 American Transplant Congress
Reasons for Match Offer Refusals and Efforts to Reduce Them in the OPTN/UNOS Kidney Paired Donation Pilot Program (KPDPP)
1UNOS, Richmond, VA; 2Carnegie Mellon Univ, Pittsburgh, PA; 3Univ Hosp Case Med Ctr, Cleveland, OH.
Background: The OPTN/UNOS KPDPP has been finding 2-way, 3-way, and chain exchanges since Oct 2010. Though the number of pairs entered, matches found, and transplants…
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