Articles tagged "Kidney transplantation"

2015 American Transplant Congress
The Value of Surveillance Testing for De Novo Donor Specific Antibodies Following Renal Transplantation
O. Pankewycz,¹ M. Laftavi,² M. Said,² K. Chapin,² L. Feng.²
¹Medicine, SUNY at Buffalo/ECMC, Buffalo, NY; ²Surgery, SUNY at Buffalo/ECMC, Buffalo, NY.
The development of de novo donor specific antibodies (dnDSA) usually leads to a reduction in renal graft survival. The deleterious influence of dnDSA is most…
2015 American Transplant Congress
NK Cells of Kidney Transplant Recipients Show a Reduced Capacity to Produce Cytokines But Retain Their Cytotoxic Capacity
U. Hoffmann,¹ C. Neudoerfl,¹ K. Daemen,¹ J. Keil,¹ C. Blume,^2,3 F. Lehner,⁴ H. Haller,² C. Falk.^1,5
¹Inst. of Transplant Immunology, IFB-Tx, Hanover Medical School, Hanover, Germany; ²Dept. of Nephrology and Hypertension, Hanover Medical School, Hanover, Germany; ³Inst. of Technical Chemistry, Leibniz University Hanover, Hanover, Germany; ⁴Dept. of General, Visceral, and Transplantation Surgery, Hanover Medical School, Hanover, Germany; ⁵German Center for Infection Research, Braunschweig, Germany.
The role of NK cells in either graft rejection or tolerance induction is still discussed controversially. In order to clarify the effect of long-term immunosuppression…
2015 American Transplant Congress
Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 48
K. Budde,¹ C. Sommerer,¹ P. Weithofer,¹ O. Witzke,¹ M. Guba,¹ J. Jacobi,¹ B. Vogt,³ I. Hauser,¹ R. Stahl,¹ P. Reinke,¹ T. Rath,¹ D. Baeumer,² M. Porstner,² M. Zeier,¹ F. Lehner,¹ W. Arns.¹
¹Herakles Study Group, Germany; ²Novartis, Pharma, Germany; ³Herakles Study Group, Switzerland.
Aim: To follow up on renal function (GFR) at month (Mo) 48 after kidney transplantation (Tx) in patients (pts) on immunosuppressive regimen with different calcineurin…
2015 American Transplant Congress
A Noninvasive Diagnostic Test of Renal Allograft Rejection Using Urinary-Cell mRNA: A Comparison of Droplet Digital and Real-Time PCR
J.-W. Seo, H. Moon, A. Lee, Y.-W. Choi, Y. Kim, J.-Y. Moon, S.-H. Lee.
Division of Nephrology, Department on Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Background: The diagnosis of acute rejection in kidney transplantation is still standardized by an invasive renal biopsy. Noninvasive tests and biomarkers that can replace the…
2015 American Transplant Congress
The Feasibility of Utilising DCD Kidneys for Paediatric Recipients: Early Outcomes
Z. Ahmed,¹ R. Batra,¹ S. Marks,³ H. Jones,⁴ N. Mamode.¹
¹Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; ²Abdominal Transplant Surgery, Mayo Clinic, Pheonix, AZ, United Kingdom; ³Paediatric Nephrology, Great Ormond Street Hospital, London, United Kingdom; ⁴Paediatric Nephrology, Evelina Children's Hospital, London, United Kingdom.
Introduction: Despite the widespread uptake of transplantation of kidneys from DCD donors, allocating such organs to paediatric recipients remains controversial; with no large case series…
2015 American Transplant Congress
Geographic Differences in HIV+ Kidney Transplant Waitlist Characteristics
J. Locke,¹ S. Gustafson,² C. Durand,³ J. Snyder,² B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ S. Mehta,¹ A. Nellore,¹ D. Segev.^2,3
¹University of Alabama, Birmingham, Birmingham, AL; ²SRTR, MMRF, Minneapolis, MN; ³Johns Hopkins University, Baltimore, MD.
Kidney transplant (KT) is now a viable option for select HIV+ end-stage renal disease (ESRD) patients. As OPTN does not collect HIV status at waitlisting,…
2015 American Transplant Congress
Effect of Center Volume On Kidney Transplant Outcomes- Mate Kidney Analysis
T. Klair,¹ P. Friedmann,² L. Kayler.²
¹Abdominal Organ Transplant & Hepatobiliary Surgery, Columbia University Medical Center, New York, NY; ²Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Background- Reports of the association of center volume and outcomes in kidney transplantation (KTX) may not provide adequate adjustment for donor risk factors. This study…
2015 American Transplant Congress
Renal Tubular Dysfunction Following Donor Nephrectomy and Its Impact On Residual Kidney Function
Z. Ahmed,¹ C. Rooney,³ C. Turner,² N. Dalton,² N. Kessaris,¹ N. Mamode.¹
¹Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; ²Wellchild Laboratory, St Thomas' Hospital, London, United Kingdom; ³Faculty of Medicine, King's College London, London, United Kingdom.
Background: Recent publications have described an increasing incidence of end stage renal disease amongst kidney donors. This highlights the paucity of knowledge which exists in…
2015 American Transplant Congress
Epidemiology of Pneumonia in a Cohort of 5,000+ Abdominal Solid Organ Transplant Recipients
A. Masica, S. Delcroix-Lopes, M. Kouznetsova, C. Spak.
Baylor Scott & White Health, Dallas, TX.
Study purposeWe evaluated the epidemiology of pneumonia (PNE) in a longitudinal cohort of patients with abdominal (kidney, liver, and/or pancreas) solid organ transplants (SOT).MethodsRetrospective study…
2015 American Transplant Congress
Favorable Results of ABO Incompatible Renal Transplantation Without B Cell Targeted Therapy: Advantages and Disadvantages of Rituximab Pretreatment
M. Okada,¹ K. Futamura,¹ K. Itou,¹ T. Yamamoto,¹ T. Hiramitsu,¹ M. Tsujita,¹ N. Goto,¹ S. Narumi,¹ Y. Watarai,¹ A. Katayama,² K. Uchida,³ T. Kobayashi.⁴
¹Nagoya Daini Red Cross Hospital, Nagoya, Japan; ²Masuko Memorial Hospital, Nagoya, Japan; ³Aichi Medical University, Nagakute, Japan; ⁴Nagoya University School of Medicine, Nagoya, Japan.
INTRODUCTIONThe outcome of ABO-incompatible transplantation (ABO-I) has been reported to be comparable to that of ABO-identical/compatible transplantation (ABO-Id/C), which is considered to be due to…