ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Immunosuppression With Anti-CD40 mAb and Rapamycin for Islet and Kidney Co-Transplantation in Nonhuman Primates

    T. Oura, K. Hotta, J. Lei, J. Markmann, A. Dehnadi, G. Benichou, B. Cosimi, T. Kawai.

    Transplant Center, Massachusetts General Hospital, Boston, MA.

    Background: For patients with end-stage renal disease secondary to type 1 diabetes mellitus, islet and kidney co-transplantation can be an ideal transplant option. However, a…
  • 2015 American Transplant Congress

    Glucose Chemical Exchange Saturation Transfer MRI of Acute Renal Allograft Rejection

    D. Kentrup,1 A. Busch,2 H. Pawelski,1 V. Hoerr,2,3 S. Reuter.1

    1Department of Medicine D, University Hospital Münster, Münster, Germany; 2Department of Clinical Radiology, University Hospital Münster, Münster, Germany; 3Institute of Medical Microbiology, Jena University Hospital, Jena, Germany.

    Purpose: During acute rejection episodes large amounts of immune cells infiltrate renal grafts, leading to inflammation accompanied by an increased glucose metabolism.Given these circumstances we…
  • 2015 American Transplant Congress

    hTERT, BICD1 and Chromosome 18 Polymorphisms Affecting Telomere Length Are Associated With Kidney Transplantation Outcome

    L. Domanski,1 K. Kloda,1 K. Safranow,2 A. Drozd,3 K. Ciechanowski,1 A. Ciechanowicz.4

    1Clinical Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland; 2Department of Biochemistry and Medical Chemistry, Pomeranian Medical University in Szczecin, Szczecin, Poland; 3Department of Biochemistry and Human Nutrition, Pomeranian Medical University in Szczecin, Szczecin, Poland; 4Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.

    Telomere length (TL) has been analyzed in regard to cell senescence and ageing of animals and humans, including age-related diseases. There have been also attempts…
  • 2015 American Transplant Congress

    Low Dose Valganciclovir Is an Effective Prophylaxis Against Cytomegalovirus in High Risk (Donor+/ Recipient-) Kidney Transplants Recipients

    S. Fayek,1 E. Beshears,1 N. Alvey,2 A. Sauer,1 R. Lieber,1 O. Olaitan,1 E. Hollinger,1 S. Jensik,1 J. Geyston,2 M. Brokhof,2 A. Hodowanec,3 D. Simon,3 M. Hertl.1

    1Surgery/Transplant, Rush University Medical Center, Chicago; 2Pharmacy, Rush University Medical Center, Chicago; 3Medicine/Infectious Diseases, Rush University Medical Center, Chicago.

    Introduction: Universal prophylaxis against Cytomegalovirus (CMV) disease is endorsed in high risk seronegative kidney (K) transplant (TX) recipients of organs from seropositive donors (D+/R-) using…
  • 2015 American Transplant Congress

    Kidney Transplantation (KTx) With Positive Crossmatch (XM) but No Donor Specific Antibody (DSA)

    J. Verbesey, O. Timofeeva, L. Dong, B. Javaid, G. Monica, A. Gilbert, J. Moore, P. Weems, S. Ghasemian, S. Rosen-Bronson, M. Cooper.

    MedStar Georgetown Transplant Institute, Washington, DC.

    Purpose: Prior to KTx, a XM is performed between the intended recipient and donor. This XM can be positive despite no DSA. It can be…
  • 2015 American Transplant Congress

    Outcomes in Kidney Transplant Recipients Over Age of 55 by Donor Source: LD, SCD, ECD

    V. Kirchner, K. Gillingham, A. Matas, The Div of Tx and Tx Nephrology.

    University of Minnesota, Mpls.

    Background: Outcomes in older kidney transplant recipients from SCD and ECD have been studied; however, comparative outcomes between older recipients of LD, SCD and ECD…
  • 2015 American Transplant Congress

    Predictive Value of Cardiovascular Risk Assessment Tools in Kidney Transplantation

    C. Dunn, A. Holtzman, M. Hung, S. Greenstein.

    Surgery, Albert Einstein College of Medicine, Bronx, NY.

    Cardiovascular disease is a major cause of morbidity and mortality following kidney transplantation. Many cardiovascular risk screening tools have been developed, but they have never…
  • 2015 American Transplant Congress

    Effect of 2007 CMS Conditions of Participation on High Risk Renal Transplantation: A Study of the United States Renal Data System

    D. John, A. Brar, F. Tedla, N. Sumrani, E. Timpo, M. Salifu.

    Division of Transplantation, SUNY Downstate Medical Center, Brooklyn, NY.

    BACKGROUND: On June 28, 2007, CMS introduced new Conditions of Participation (CoP) for Transplant Centers- the impact of these regulations on adult patients at high…
  • 2015 American Transplant Congress

    Customized Reminders and Provider Notification to Improve Adherence to Immunosuppression

    P. Reese, R. Bloom, J. Trofe-Clark, A. Mussell, D. Leidy, S. Levsky, J. Zhu, Y. Lin, A. Troxel, H. Feldman, K. Volpp.

    UPenn, Philadelphia, PA.

    Background: Non-adherence to transplant immunosuppression is associated with an elevated risk of allograft loss. Novel, wireless-enabled pill bottles have created the opportunity to monitor patient…
  • 2015 American Transplant Congress

    Microvascular (MIA) and Interstitial (i) Inflammation Influence Late Death-Censored Graft Failure (DCGF) After Kidney Transplantation

    R. Gaston,1 A. Fieberg,2 R. Leduc,2 J. Connett,2 F. Cosio,3 S. Gourishankar,4 J. Grande,3 L. Hunsicker,5 B. Kasiske,6 J. Cecka,7 A. Matas,2 D. Rush.8

    1UAB, Birmingham; 2U Minnesota, Minneapolis; 3Mayo Clinic, Rochester; 4U Alberta, Edmonton, Canada; 5U Iowa, Iowa City; 6Hennepin County Med Ctr, Minneapolis; 7UCLA Immunogenetics, Los Angeles; 8U Manitoba, Winnipeg, Canada.

    We and others have shown late DCGF is due to ongoing, most often immune, injury. Though there is general agreement that antibody-mediated injury is a…
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