Articles tagged "Kidney transplantation"

2015 American Transplant Congress
The Potential of E-Health to Improve Adherence: Exploring the Patients' View
D. Slaats,¹ M. Tielen,¹ M. Laging,¹ T. van Gelder,² W. Weimar,¹ E. Massey.¹
¹Internal Medicine, Erasmus MC, Rotterdam, Netherlands; ²Internal Medicine and Hospital Pharmacology, Erasmus MC, Rotterdam, Netherlands.
Introduction. Transplant outcomes can be negatively influenced by medication nonadherence. Therefore, there is a need for effective interventions to improve adherence. In recent years due…
2015 American Transplant Congress
A Non-Invasive Urinary Common Rejection Module (uCRM) Gene Expression Score Enables Accurate Discrimination of Acute Rejection in Kidney Transplant Patients
O. Bestard,^1,2 T. Sigdel,¹ Y. Ng,¹ S.-C. Hsieh,¹ S. Roedder,¹ N. Dvorak,¹ T. Tran,¹ M. Sarwal.¹
¹Department of Transplant Surgery, UCSF, San Francisco, CA; ²Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, CAT, Spain.
A common rejection module (CRM) consisting of 11 genes expressed on allograft biopsies was recently shown to be highly accurate to discriminate patients undergoing acute…
2015 American Transplant Congress
Pre-Transplant Levels of TFH cell-Inducing Pro-Inflammatory Cytokines Correlate With DSA Formation After Kidney Transplantation
C. Macedo,¹ K. Hadi,¹ B. Elinoff,¹ M. Marrari,¹ A. Zeevi,¹ B. Ramaswami,¹ G. Chalasani,¹ A. Shields,² R. Alloway,³ E. Woodle,² F. Lakkis,¹ D. Metes.¹
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh; ²Surgery, University of Cincinnati College of Medicine, Cincinnati; ³Internal Medicine-Nephrology, University of Cincinnati College of Medicine, Cincinnati.
Donor-specific anti-HLA antibodies (DSA) represent an important biomarker for acute rejection and are a major cause of long-term graft failure after kidney transplantation (KTx). The…
2015 American Transplant Congress
No Tumor Recurrence After Renal Cell Carcinoma Resected Kidney Transplantation – 5 Year Follow Up
M. Zwierzchoniewska,¹ K. Fong,¹ D. Patel,¹ L. Mou, W. Lim,² B. He,¹ L. Delriviere.¹
¹Western Australian Kidney Transplant Surgery Service, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia; ²Western Australian Kidney Transplant Service, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
INTRODUCTION:Organ shortage remains the single most significant impediment to increasing low rate of kidney transplantation. One of the strategies to improve it, is a utilisation…
2015 American Transplant Congress
CPRA Values Are Substantially Increased for Some Candidates Subsequent to Inclusion of Unacceptable C-locus (UA-C) Antigens While Listing Practices Remain Unchanged
A. Kucheryavaya,¹ R. Bray,² A. Miller,¹ D. Tyan.³
¹UNOS, Richmond; ²Emory University Hospital, Atlanta; ³Stanford University, Palo Alto.
Background: CPRA is the % of deceased donors expected to have one or more UAs with a given candidate. Prior to 12/5/13, candidates with UA-C…
2015 American Transplant Congress
Pharmacokinetics of Tacrolimus (TAC) in Elderly Compared to Young Recipients in the First Year After Renal Transplantation. Data from the NEverOLd Trial
E. David-Neto,¹ P. Romano,² A. Triboni,¹ F. Agena,¹ P. Ebner,² F. Ramos,¹ N. Galante,¹ F. Lemos.¹
¹Renal Transplantation Service, Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil; ²Division of Central Laboratory, Hospital das Clinicas – University of São Paulo School of Medicine, Sao Paulo, Brazil.
Elderly (≥60years) recipients are nowadays receiving renal transplants more frequently. The pharmacokinetics studies (PK) of immunosuppressive drugs in healthy volunteers, rarely, if ever, include old…
2015 American Transplant Congress
Reduced Intensity Immunosuppression Protocol Lowers Drug Costs and May Decrease Incidences of BK Viremia and Readmissions After Kidney and Kidney/Pancreas Transplant
M. Mariski,¹ A. DeGolovine,² W. Dar,² J. Bynon,² H. Adrogué,² M. Hobeika.²
¹Dept of Pharmacy, Memorial Hermann Texas Medical Center, Houston, TX; ²Division of Immunology and Organ Transplantation, University of Texas, Houston, TX.
Purpose: To evaluate the effects of a reduced intensity immunosuppression protocol on drug costs and rates of BK viremia and readmissions.Methods: In response to high…
2015 American Transplant Congress
The Clinical Outcome of Plasma Cell-Rich Rejection of Kidney Allograft
J. Hasegawa,¹ K. Honda,² S. Wakai,¹ H. Shirakawa,³ M. Okumi,³ K. Omoto,³ H. Ishida,³ K. Tanabe.³
¹Nephrology, Ohkubo Hospital, Tokyo, Japan; ²Pathology, Tokyo Women's Medical University, Tokyo, Japan; ³Urology, Tokyo Women's Medical University, Tokyo, Japan.
Background: Plasma cell-rich rejection (PCRR) is a rare type of allograft rejection characterized by the presence of mature plasma cells. This type of rejection has…
2015 American Transplant Congress
Living Donor Transplant Rates in Children Are Declining
D. Keith, A. Nishio Lucar, G. Vranic.
University of Virginia, Charlottesville, VA.
Living donor (LD) transplant rates have been declining since 2004 in adult candidates. We sought to determine if this trend is also occurring in pediatric…
2015 American Transplant Congress
Noninvasive Diagnostic and Predictive Value in Renal Transplant Recipients by Measurement of Urine BCA-1
D. Chen, J. Chen, W. Peng.
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Key Laboratory of Nephropathy, Zhejiang Province; Kidney Disease Immunology Laboratory, The Third Grade Laboratory, State Administration of Traditional Chinese.
ObjectiveTo investigate the relationship between early-stage renal acute rejection and the level of BCA-1 in urine, explore the diagnostic value and noninvasive monitoring in early…