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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    Failure to Account for Critical Candidate Characteristics Significantly Biases Kidney Transplant Center Report Cards Measuring Time to Transplant

    L. Kayler,1 J. Schold.2

    1Surgery, Montefiore Medical Center, Bronx, NY; 2Medicine, Cleveland Clinic, Cleveland, OH.

    Kidney transplant rate is proposed to be integrated into the new composite metric to evaluate center performance. Current methods adjust for PRA, blood type, re-transplantation,…
  • 2015 American Transplant Congress

    Prediction of Acute Antibody Mediated Rejection in Antibody Incompatible Renal Transplantation Using Machine Learning for Wide Data

    T. Shaikhina,1 N. Khovanova,1 S. Daga,1,3 N. Krishnan,2 D. Lowe,3 D. Mitchell,1 D. Briggs,2 R. Higgins.3

    1University of Warwick, Coventry, United Kingdom; 2NHS Blood and Transplant, Birmingham, United Kingdom; 3University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.

    The dynamic field of renal transplantation is characterised by limited access to data, the high cost of equipment and underlying complexity of immunological responses to…
  • 2015 American Transplant Congress

    MicroRNAs in Kidney Graft Preservation Fluid as Novel Biomarkers for Delayed Graft Function

    L. Ooms, H. Roest, S. van den Hoek, R. de Bruin, J. IJzermans, L. van der Laan, F. Dor.

    Transplant Surgery, Erasmus Medical Center, Rotterdam, Netherlands.

    Introduction: Delayed graft function is a common complication after deceased donor kidney transplantation (KT), which affects both short and long-term outcome. Currently available biomarkers in…
  • 2015 American Transplant Congress

    Robotic Kidney Transplantation in Obese Recipients Can Lead to Superior Outcomes in Terms of Wound Infection and Graft Survival

    I. Tzvetanov, G. D'Amico, G. Georgiev, P. Giulianotti, H. Jeon, R. Garcia-Roca, J. Oberholzer, E. Benedetti.

    Surgery, Division of Transplantation, University of Illinois at Chicago, Chicago, IL.

    IntroductionTraditionally kidney transplantation (KT) in obese recipients has been associated with high rates of surgical site infections (SSI). We hypothesize that robotic kidney transplantation (RKT)…
  • 2015 American Transplant Congress

    Induction Therapy Improves 15-Year Graft Survival in Kidney Transplant Recipients With Acute Rejection

    R. Bajoka, M. Goggins, A. Patel.

    Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Background: Graft(GS) and patient survival(PS) has been shown to be superior in patients without delayed graft function (DGF) or acute rejection(AR). Induction therapy(IT) is frequently…
  • 2015 American Transplant Congress

    Hybrid-Natural Orifice Transluminal Endoscopic Surgery (NOTES) for Laparoscopic Donor Nephrectomy Offers Better Postoperative Pain, Cosmesis and Surgical Outcomes Than Transumbilical Single Site Surgery

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Laparoendoscopic single site donor nephrectomy (LESSDN) via the umbilicus has been our standard care for living donors. Although we have previously reported better cosmetic…
  • 2015 American Transplant Congress

    1-Year Safety and Efficacy of Eculizumab in Adult aHUS Patients, With or Without a History of Renal Transplant

    C. Legendre,1 J. Kincaid,2 C. Bedrosian,2 C. Loirat.3

    1University Paris Descartes & Hôpital Necker, Paris, France; 2Alexion, Cheshire, CT; 3Assistance Publique–Hôpitaux Paris, Hôpital Robert-Debré, Paris, France.

    Background: Atypical hemolytic-uremic syndrome (aHUS) is a life-threatening, chronic disease of complement-mediated TMA. In aHUS, renal transplantation is associated with post-transplant (TP) TMA and ∼50–70%…
  • 2015 American Transplant Congress

    Rat dnIKK2-Treg Derived Exosomes Suppress T Cell Proliferation, Generate T Regulatory Cells and Prolong Kidney Allograft Survival

    S. Aiello, F. Rocchetta, N. Azzollini, S. Tomasoni, G. Remuzzi, M. Noris, A. Benigni.

    Istituto di Ricerche Farmacologiche Mario Negri, Ranica, Italy.

    Rat DCs, made immature by adenoviral gene transfer of dnIKK2, generated in MLR a unique population of CD4+ T regulatory cells (dnIKK2-Treg) which potently inhibited…
  • 2015 American Transplant Congress

    Associations of Pre-Transplant Prescription Narcotic Use With Clinical Complications After Kidney Transplantation

    N. Lam,1 M. Schnitzler,2 J. Tuttle-Newhall,2 H. Xiao,2 D. Axelrod,3 D. Brennan,4 V. Dharnidharka,4 M. Nazzal,2 K. Lentine.2

    1Western University, London, ON, Canada; 2Saint Louis University, St. Louis, MO; 3Dartmouth Hitchcock Medical Center, Hanover, NH; 4Washington University School of Medicine, St. Louis, MO.

    Background: Associations of narcotic use before kidney transplantation with post-transplant clinical outcomes are not well described.Methods: We performed a retrospective analysis of linked national registry…
  • 2015 American Transplant Congress

    Hypothermic Machine Perfusion Improves Kidney Viability through Amelioration of Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells

    Z. Zhong,1 Z. Liu,1 Z. Fu,2 Y. Zhang,2 D. Ko,3 Y. Wang,1 Q. Ye.1,2

    1Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, China; 2The 3rd Xiangya Hospital of Central South University, Research Center of National Health Ministry on Transplantation Medicine Engineering and Technology, Changsha, Hunan, China; 3Massachusetts General Hospital, Department of Urology, Boston, MA.

    Hypothermic machine perfusion (MP) may improve outcome after transplantation from donors after cardiac death (DCD) kidneys, but protective mechanisms of MP remain largely unknown. To…
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