ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2015 American Transplant Congress

    CD8 T Cell Biomarkers Improves the Capacities of the Kidney Transplant Failure Score for the Long-Term Prognostic of Kidney Graft Failures

    N. Degauque,1,2 M. Yap,1 G. Tilly,1,3 P. Guerrif,2 M. Giral,2 S. Brouard,1,2 Y. Foucher.2,3

    1INSERM UMR1064, Nantes, France; 2CHU de Nantes, Nantes, France; 3University of Nantes, Nantes, France.

    Background. Kidney transplantation is acknowledged as the treatment of choice for patients in end-stage renal disease compared to dialysis. We hypothesized that the efficiency of…
  • 2015 American Transplant Congress

    Living Donor Gifted Lithiasis: Outcomes in Kidney Transplant Recipients

    M. Mujtaba, C. Sundaram, M. Yaqub, T. Taber, J. Powelson, S. Doshi, A. Sharfuddin.

    Indiana University, Indianapolis.

    BACKGROUND: The presence of kidney stones has been a relative contraindication for living donation. The long term outcomes and safety of kidney transplant recipients of…
  • 2015 American Transplant Congress

    Single Center Experience of C4d Staining of Kidney Transplant Biopsies

    R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.

    Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…
  • 2015 American Transplant Congress

    Plasma 4β-Hydroxycholesterol Measurement as a Potential Biomarker for CYP3A5 Activity in Informing Tacrolimus Dosing

    T. Elnahhas,1,2 E. de Jonge,4 T. Lee,2 B. van Zelst,4 J. Popoola,3 R. Ramkhelawon,3 R. van Schaik,4 A. Johnston,1,2 I. MacPhee.3

    1Clinical Pharmacology, Queen Mary University of London, London, United Kingdom; 2Analytical Services International, St.George's University of London, London, United Kingdom; 3Institute of Medical and Biomedical Education-Renal Medicine, St.George's University of London, London, United Kingdom; 4Clinical Chemistry, Erasmus MC Rotterdam, Rotterdam, Netherlands.

    Background—Recently, 4β-hydroxycholesterol (4β-OHC) has been shown to be an endogenous marker of P450 3A activity in clinical practice (Diczfalusy et al, 2011). 4β-OHC concentration increases…
  • 2015 American Transplant Congress

    Conversion from Immediate to Prolonged Release Tacrolimus Did Not Change Intra-Patient Variability in Renal Transplant Patients

    T. El-Nahhas,1,2 M. Moreton,2 J. Popoola,3 S. Abat,3 A. Johnston,1,2 I. MacPhee.3

    1Clinical Pharmacology Department, William Harvey Research Institute, Barts and The London, Queen Mary University of London, London, United Kingdom; 2Analytical Services International, St. George's University of London, London, United Kingdom; 3Institute of Medical and Biomedical Education-Renal Medicine, St. George's University of London, London, United Kingdom.

    Background. Tacrolimus has a narrow therapeutic index and is characterized by a large inter- and intra-patient variability (IPV). Variable blood tacrolimus concentrations have been shown…
  • 2015 American Transplant Congress

    Impact of Subclinical Rejection (SCR) and Acute Clinical (ACR) in Renal Transplant Recipients

    R. Mehta, P. Sood, A. Cherukuri, S. Chen, G. Mour, C. Wu, N. Shah, C. Puttarajappa, P. Randhawa, A. Tevar, S. Hariharan.

    University of Pittsburgh Medical Center, Pittsburgh, PA.

    The importance of diagnosing subclinical rejection and its short and long term impact remains controversial.We prospectively evaluated 296 patients who had a kidney transplant at…
  • 2015 American Transplant Congress

    The Impact of Ureteral Complications After Pediatric Renal Transplantation

    J. Finkelstein,1 J. Pak,1 N. Jain,1 P. Sandoval,2 S. Alam.1

    1Pediatric Urology/Nephrology, Morgan Stanley Children's Hospital, New York, NY; 2Surgery, Columbia University College of Physicians & Surgeons, New York, NY.

    Introduction: The incidence of acute renal allograft rejection has declined with advances in immunosuppression, making the evaluation of other risk factors for graft failure vital.…
  • 2015 American Transplant Congress

    Incidence of Hepatitis B Virus Reactivation in Kidney Transplant Patients Who Received Rituximab Administration

    K. Omoto, M. Okumi, D. Toki, T. Shimizu, H. Ishida, K. Tanabe.

    Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.

    OBJECTIVE:The efficacy of antiviral prophylaxis for rituximab (RIT)-associated hepatitis B virus (HBV) reactivation in patients with lymphoma has been recently reported. However, the immunological effect…
  • 2015 American Transplant Congress

    Transplantation of Neonatal En-Bloc Kidneys: Do They Grow and Are They Subject to Hyperfiltration Injury?

    J. Woloszyn, C. Santhanakrishnan, C. Troppmann, A. DeMattos, B. Gallay, J. McVicar, J. Sageshima, R. Perez.

    UC Davis Transplant Center, Sacramento, CA.

    Importance:Neonatal Intensive Care Unit (NICU) kidney donation is rare but a potentially significant kidney source. Concerns with using these small kidneys include the risk for…
  • 2015 American Transplant Congress

    Matching Strategies in Kidney Paired Donation: A 7-Year Analysis of a Multi-Institutional Registry

    D. Fumo,1,2 L. Reece,2 S. Stepkowski,1 V. Kapoor,1 S. Rees,2 J. Kopke,2 M. Rees.1,2

    1University of Toledo Medical Center, Toledo, OH; 2Alliance for Paired Donation, Maumee, OH.

    Failure to convert computer-identified possible Kidney Paired Donation (KPD) exchanges into transplants has prevented KPD from reaching its full potential. The purpose of this study…
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