Articles tagged "Kidney transplantation"

2015 American Transplant Congress
Expanding the Living Donor Pool: Results of ABO Incompatible Living Related Kidney Transplantation
T. Vowinkel,¹ S. Reuter,² C. Anthoni,¹ N. Senninger,¹ B. Suwelack,² H. Wolters.¹
¹Department of General and Visceral Surgery, University Hospital Muenster, Muenster, Germany; ²Department of Medicine D, University Hospital Muenster, Muenster, Germany.
Background: Organ shortage has led to an increase in living related kidney transplantation. Here we report on our program of expanding the living donor pool…
2015 American Transplant Congress
Investigating Role of Early VTE Chemoprophylaxis in Kidney Transplant
D. Kendrick,¹ E. Kudlaty,¹ A. Kim,¹ P. Moorehead,¹ J. Augustine,² E. Sanchez,² V. Kashyap,¹ K. Woodside.²
¹Vascular Surgery, University Hospitals-Case Medical Center, Cleveland, OH; ²Transplant Institute, University Hospitals-Case Medical Center, Cleveland, OH.
Objective: Our objective was to determine whether the rate of venothromboembolic events (VTE) varied with early versus delayed prophylaxis administration. Associated bleeding complications were also…
2015 American Transplant Congress
Increased Vascular Stiffness in Pediatric Renal Transplant Recipients Despite Normal Kidney Function, Blood Pressure, and Body Mass Index
M. Seifert,^1,2 N. Kulsum-Mecci,² L. de las Fuentes,² V. Davila-Roman,² K. Hruska.²
¹Southern Illinois University, Springfield, IL; ²Washington University, St. Louis, MO.
Background: Chronic kidney disease (CKD) imparts enormous cardiovascular (CV) risk that is only partially improved by renal transplantation. We sought to understand the determinants of…
2015 American Transplant Congress
Serum Osteoprotegerin Levels Positively Correlate With Peripheral Arterial Stiffness in Kidney Transplantation Patients
M.-C. Lee,^1,2 G.-J. Ho,¹ Y.-C. Chen,¹ B.-G. Hsu.²
¹Department of Surgery, Tzu Chi General Hospital, Hualien, Taiwan; ²Department of Medicine, School of Medicine Tzu Chi University, Hualien, Taiwan; ³Department of Medicine, Tzu Chi General Hospital, Hualien, Taiwan.
Objective: Recent studies found osteoprotegerin (OPG) is associated with increased pulse wave velocity and may reflect endothelial dysfunction. The aim of this study was to…
2015 American Transplant Congress
The Value of Surveillance Testing for De Novo Donor Specific Antibodies Following Renal Transplantation
O. Pankewycz,¹ M. Laftavi,² M. Said,² K. Chapin,² L. Feng.²
¹Medicine, SUNY at Buffalo/ECMC, Buffalo, NY; ²Surgery, SUNY at Buffalo/ECMC, Buffalo, NY.
The development of de novo donor specific antibodies (dnDSA) usually leads to a reduction in renal graft survival. The deleterious influence of dnDSA is most…
2015 American Transplant Congress
NK Cells of Kidney Transplant Recipients Show a Reduced Capacity to Produce Cytokines But Retain Their Cytotoxic Capacity
U. Hoffmann,¹ C. Neudoerfl,¹ K. Daemen,¹ J. Keil,¹ C. Blume,^2,3 F. Lehner,⁴ H. Haller,² C. Falk.^1,5
¹Inst. of Transplant Immunology, IFB-Tx, Hanover Medical School, Hanover, Germany; ²Dept. of Nephrology and Hypertension, Hanover Medical School, Hanover, Germany; ³Inst. of Technical Chemistry, Leibniz University Hanover, Hanover, Germany; ⁴Dept. of General, Visceral, and Transplantation Surgery, Hanover Medical School, Hanover, Germany; ⁵German Center for Infection Research, Braunschweig, Germany.
The role of NK cells in either graft rejection or tolerance induction is still discussed controversially. In order to clarify the effect of long-term immunosuppression…
2015 American Transplant Congress
Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 48
K. Budde,¹ C. Sommerer,¹ P. Weithofer,¹ O. Witzke,¹ M. Guba,¹ J. Jacobi,¹ B. Vogt,³ I. Hauser,¹ R. Stahl,¹ P. Reinke,¹ T. Rath,¹ D. Baeumer,² M. Porstner,² M. Zeier,¹ F. Lehner,¹ W. Arns.¹
¹Herakles Study Group, Germany; ²Novartis, Pharma, Germany; ³Herakles Study Group, Switzerland.
Aim: To follow up on renal function (GFR) at month (Mo) 48 after kidney transplantation (Tx) in patients (pts) on immunosuppressive regimen with different calcineurin…
2015 American Transplant Congress
A Noninvasive Diagnostic Test of Renal Allograft Rejection Using Urinary-Cell mRNA: A Comparison of Droplet Digital and Real-Time PCR
J.-W. Seo, H. Moon, A. Lee, Y.-W. Choi, Y. Kim, J.-Y. Moon, S.-H. Lee.
Division of Nephrology, Department on Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Background: The diagnosis of acute rejection in kidney transplantation is still standardized by an invasive renal biopsy. Noninvasive tests and biomarkers that can replace the…
2015 American Transplant Congress
The Feasibility of Utilising DCD Kidneys for Paediatric Recipients: Early Outcomes
Z. Ahmed,¹ R. Batra,¹ S. Marks,³ H. Jones,⁴ N. Mamode.¹
¹Renal and Pancreatic Transplantation, Guy's Hospital, London, United Kingdom; ²Abdominal Transplant Surgery, Mayo Clinic, Pheonix, AZ, United Kingdom; ³Paediatric Nephrology, Great Ormond Street Hospital, London, United Kingdom; ⁴Paediatric Nephrology, Evelina Children's Hospital, London, United Kingdom.
Introduction: Despite the widespread uptake of transplantation of kidneys from DCD donors, allocating such organs to paediatric recipients remains controversial; with no large case series…
2015 American Transplant Congress
Geographic Differences in HIV+ Kidney Transplant Waitlist Characteristics
J. Locke,¹ S. Gustafson,² C. Durand,³ J. Snyder,² B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ S. Mehta,¹ A. Nellore,¹ D. Segev.^2,3
¹University of Alabama, Birmingham, Birmingham, AL; ²SRTR, MMRF, Minneapolis, MN; ³Johns Hopkins University, Baltimore, MD.
Kidney transplant (KT) is now a viable option for select HIV+ end-stage renal disease (ESRD) patients. As OPTN does not collect HIV status at waitlisting,…