Articles tagged "Kidney transplantation"

2015 American Transplant Congress
External Validation of Clinical Prediction Models of Patient and Graft Survival in a Canadian Cohort of Kidney Transplant Recipients
S. Singh,^1,2 D. Naimark,^1,2,3 J. Victor,² J. Kim.^1,2,4,5
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; ³Division of Nephrology, Sunnybrook Health Sciences Center, Toronto, ON, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, University Health Network, Toronto, ON, Canada; ⁵Division of Nephrology and the Renal Transplant Program, St. Michael's Hospital, Toronto, ON, Canada.
Background: Several clinical prediction models (CPM) of patient and graft survival in kidney transplant recipients have been developed as tools to assist physicians in identifying…
2015 American Transplant Congress
Lack of Utilization of Pre-Emptive Transplantation in Those With Living Donor Kidney Transplants
A. Sakhuja,¹ A. Naik,¹ R. Eikstadt,² P. Shrivastava,¹ D. Cibrik,¹ M. Samaniego.¹
¹Division of Nephrology, University of Michigan, Ann Arbor, MI; ²KECC, University of Michigan, Ann Arbor, MI.
Introduction: Time spent on dialysis before kidney transplantation (KTx) has been associated with worse outcomes. Pre-emptive transplants are not always possible due shortage of deceased…
2015 American Transplant Congress
Effect of Intrapatient Variability and Mean Tacrolimus Levels in Renal Transplant Patients
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
IntroductionNonadherence (NA) to immunosuppressive medication and adherence to immunosuppressive protocols is a potent risk factor for rejection and graft loss, which can be both patient…
2015 American Transplant Congress
Incidence and Outcomes of Polyomavirus Infection in 639 Kidney Transplant Recipients: Are High Immunological Risk Characteristics More Relevant Than Specific Induction Or Maintenance Immunosuppressive Regimens?
E. Favi,¹ L. Harris,² J. Worsfold,² R. Cacciola,¹ C. Puliatti,¹ C. Sammartino,¹ R. Sivaprakasam.¹
¹Transplantation, Royal London Hospital, London, United Kingdom; ²Barts and The London School of Medicine and Dentistry, London, United Kingdom.
Introduction. Polyomavirus-associated nephropathy (PVAN) is now recognized as an important cause of graft dysfunction and early kidney transplant loss. Over-immunosuppression is the main risk factor…
2015 American Transplant Congress
Quality of Life in Elderly Kidney Transplant Recipients over 70 Years of Age
B. Rouphael, S. Reule, A. Matas, H. Ibrahim.
Department of Medicine, University of Minnesota, Minneapolis, MN.
Objectives:Kidney transplantation in the elderly provides a survival advantage in comparison with those who remain on dialysis. However, the impact of transplantation on the quality…
2015 American Transplant Congress
Outcomes Following Kidney Transplant With Low Level Positive Flow Cytometric Crossmatch
C. Schinstock, F. Cosio, M. Gandhi, L. Cornell, M. Stegall.
Mayo Clinic, Rochester, MN.
Introduction: Highly-sensitized kidney transplant (KTx) candidates have difficulty finding a negative crossmatch donor. KTx with low level positive crossmatch might be the next best option.…
2015 American Transplant Congress
Incidence of De Novo Donor Specific Antibodies in Kidney Transplant Recipients
C. Staino, N. Pilch, O. Moussa, K. Boyle, J. Casale, K. Covert, J. Fleming, D. Taber, H. Meadows, C. Mardis, K. Chavin, S. Nadig, J. McGillicuddy, C. Bratton, T. Srinivas, P. Baliga.
MUSC, Charleston, SC.
The reported incidence and risk factors for the development of de novo donor specific antibodies (dnDSA) are variable. Although dnDSA is a negative predictor of…
2015 American Transplant Congress
Three Year Outcomes of Renal Allograft Transplants in African American Recipients Receiving Alemtuzumab for Induction Immunosuppression
P. Vaitla, H. Bohorquez, A. Cohen, A. Cruz, U. Patel, S. Anders, C.-S. Catherine, A. Moiz, S. Guisti, I. Carmody, G. Loss, D. Bruce, T. Reichman, J. Garces.
Ochsner Clinic Foundation, New Orleans, LA.
Background:Induction with Alemtuzumab is well documented to reduce the incidence and severity of acute rejection episodes, which may improve graft survival. Limited data are available…
2015 American Transplant Congress
The Role of Immunosuppression on Cardiac Functions of Kidney Transplant Recipients
U. Cakir, O. Cavdaroglu, T. Erturk, E. Gurluler, A. Gurkan, I. Berber.
Transplant Center, Acibadem University, Istanbul, Turkey.
Cardiac disorders are associated with high morbidity and mortality in end-stage renal disease (ESRD).Kidney transplantation is known to increase the survival of dialysis patients by…
2015 American Transplant Congress
Early Antibody Mediated Rejection in HLA Antibody Incompatible Kidney Transplantation – A Treatable Condition Without Heavy Induction Immunosuppression
S. Daga,^1,2 N. Krishnan,¹ D. Lowe,³ F. Lam,¹ C. Imray,^1,2 H. Kashi,¹ L. Tan,¹ D. Briggs,³ R. Higgins.^1,2
¹Renal Department, University Hospital, Coventry, United Kingdom; ²Warwick Medical School, University of Warwick, Coventry, United Kingdom; ³H&I Department, NHSBT, Birmingham, United Kingdom.
Transplantation across preformed donor specific HLA antibodies (DSA) not only carries a risk of early acute antibody mediated rejection (AMR) and graft loss, but also…