2022 American Transplant Congress
Robotic-Assisted Reconstruction of the Transplant Ureter: A Minimally Invasive Option for a Rare Complication
*Purpose: Ureteric stricture are rare after kidney transplants but nonetheless this complication requires reconstruction in the majority of cases to avoid graft dysfunction and/or failure.…2022 American Transplant Congress
Lipid Metabolism Profile of Human Kidneys During Ex Vivo Normothermic Perfusion
UC Davis Medical Center, Sacramento, CA
*Purpose: The kidney is a highly metabolic organ and lipids are an important energy source. In this study, we examined the lipid profiles of discarded…2022 American Transplant Congress
Dd-cfdna Correlates With Acute Rejection In The Setting Of Bk Viremia After Kidney Transplantation
1NYU Langone Transplant Institute, New York, NY, 2CareDx, Brooklyn, NY
*Purpose: BK virus reactivation is common among kidney transplant recipients (KTRs) and is a risk factor for allograft loss. Currently, there is no clearly established…2022 American Transplant Congress
Validation of the iBox Surrogate End Point in CNI Free, Belatacept Treated Patients (BENEFIT & BENEFIT-EXT)
*Purpose: The iBox is a prognostication system for long-term kidney allograft survival, developed with mostly patients under a CNI based immunosuppression. Patients treated with a…2022 American Transplant Congress
IL-15 Signaling is Required for the Maintenance of Tissue Resident Memory T Cells in Chronic Allograft Rejection
1Starzl Transplantation Institute, Pittsburgh, PA, 2JN Biosciences, Mountain View, CA
*Purpose: Currently, no immunotherapies have been clinically proven to prevent or treat chronic rejection. IL-15 is known to support memory T cell homeostasis. However, it…2022 American Transplant Congress
Tacrolimus Exposure Estimation in Stable Kidney Transplant Recipients Using Maximum A Posteriori Bayesian Approach
*Purpose: Tacrolimus exhibits interpatient pharmacokinetic variability that impacts clinical responses and requires routine trough therapeutic drug monitoring. Tacrolimus troughs do not consistently predict area under…2022 American Transplant Congress
Urinary Cell CTOT-04 Signature is Diagnostic of Glomerulitis in Kidney Allograft Biopsies
1Nephrology, Weill Cornell-NYPH, New York, NY, 2Pathology, Weill Cornell-NYPH, New York, NY
*Purpose: Antibody mediated rejection is a significant complication after kidney transplantation and is an important cause of allograft failure. In the multicenter CTOT-04 study, we…2022 American Transplant Congress
Treading the Paradigm Shift: A Single Center Comparative Study of Outcomes Between Pre-Emptive and Early Kidney Transplant with Non Pre-Emptive Kidney Transplant Recipients Innational Kidney and Transplant Institute
*Purpose: To compare the 3-year outcome of pre-emptive and early kidney transplant recipients versus non pre-emptive recipients in our institution from January 2013 to December…2022 American Transplant Congress
Correlation of Donor-Derived Cell-Free DNA with Histology and Molecular Diagnoses of T-cell Mediated Rejection in Kidney Transplant Biopsies
1Virginia Commonwealth University, Richmond, VA, 2University of Alberta, Edmonton, AB, Canada
*Purpose: We have reported the correlation of donor-derived cell-free DNA (dd-cfDNA) with histologic and molecular diagnosis (MMDx) of kidney transplant biopsies (Gupta et al, Transplantation…2022 American Transplant Congress
A More Equitable Transplant Evaluation: What Patient-Level Factors Impact Time to Kidney Transplant Evaluation Completion?
Houston Methodist, Houston, TX
*Purpose: The kidney transplant evaluation process can take months or years to complete depending on patient health status and level of engagement. This study examines…
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