ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Avoidance of CNI and Steroids Using Belatacept – A Preliminary Report of CTOT-16.

    R. Mannon,1 P. Stock,2 A. Mehta,3 D. Ikle,4 N. Watson,5 N. Bridges,5 M. Robien,5 K. Newell.3

    1UAB, Birmingham; 2UCSF, San Francisco; 3Emory, Atlanta; 4Rho, Chapel Hill; 5NIAID, Bethesda.

    CTOT-16 tested the hypothesis that belatacept used as maintenance immunosuppression (IS) in kidney transplantation would allow the long-term avoidance of CNI and corticosteroids. Methods: Primary…
  • 2016 American Transplant Congress

    Urine Cell-Free Supernatant Metabolites Diagnostic of Antibody Mediated Rejection in Kidney Allografts.

    M. Alkadi,1 J. Lee,1 D. Dadhania,1 T. Muthukumar,1 C. Snopkowski,1 C. Li,1 S. Salvatore,1 S. Seshan,1 K. Suhre,2 M. Suthanthiran.1

    1Weill Cornell Medicine, NY; 2Weill Cornell Medical College-Qatar, Doha, Qatar.

    Introduction:Urine cell-free supernatant metabolite profiles provide a unique opportunity to interrogate intra-graft processes and have distinguished acute cellular rejection from no rejection in the Clinical…
  • 2016 American Transplant Congress

    Anti-IL6R Therapy (Tocilizumab) Improves Long-Term Patient & Graft Survival in Patients with Chronic Antibody-Mediated Rejection and Transplant Glomerulopathy.

    J. Choi, A. Vo, M. Haas, D. Puliyanda, S. Louie, A. Peng, J. Kahwaji, R. Villicana, I. Kim, J. Mirocha, S. Jordan.

    Comprehensive Transplantation Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction:Extending the functionality of renal allografts is an essential goal of transplant medicine. HS patients (pts) are at increased risk for chronic ABMR (CABMR) due…
  • 2016 American Transplant Congress

    Black Ethnicity as a Risk Factor for Poor Kidney Allograft Outcomes Post-Transplantation.

    S. Tahir,1 F. Jackson-Spence,1 H. Gillott,1 F. Everson,2 J. Nath,2 A. Sharif.2

    1University of Birmingham, Birmingham, United Kingdom; 2Queen Elizabeth Hospital, Birmingham, United Kingdom.

    Introduction: Registry studies, largely from the United States, have consistently demonstrated inferior outcomes for black patients undergoing renal transplant. A recent Canadian publication has challenged…
  • 2016 American Transplant Congress

    Impact of Delayed Graft Function Varies by Demographic and Clinical Characteristics in Deceased Donor Kidney Transplantation.

    C. Liao, A. Massie, S. Bae, A. Muzaale, D. Segev.

    JHU, Baltimore.

    Single-center studies have suggested potential differences in the impact of DGF by recipients' biological susceptibility, quality of allograft, and immune compatibility. The goal of this…
  • 2016 American Transplant Congress

    Epitope Load Is Predictive of De Novo Donor Specific Antibodies Occurrence in Renal Transplant Recipients After Conversion from Cyclosporine to Everolimus.

    R. Snanoudj,1 C. Suberbielle,2 N. Kamar,3 E. Cassuto,4 S. Caillard,5 J.-L. Taupin,2 D. Anglicheau,1 C. Legendre,1 A. Hertig,6 E. Rondeau.6

    1Necker Hospital, Paris, France; 2Saint-Louis Hospital, Paris, France; 3Rangueil Hospital, Toulouse, France; 4Pasteur Hospital, Nice, France; 5CHRU, Strasbourg, France; 6Tenon Hospital, Paris, France.

    IntroductionThe degree of HLA compatibility between donor and recipient is an important risk factor of developing de novo DSA, but misjudged by the number of…
  • 2016 American Transplant Congress

    MicroRNAs in Urinary Sediments as Non-Invasive Tool to Detect Acute Rejection After Kidney Transplantation.

    E. Gielis,1,2 J. Anholts,2 H. de Fijter,3 I. Bajema,4 F. Claas,2 M. Eikmans.2

    1Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium; 2Immunohematology, LUMC, Leiden, Netherlands; 3Nephrology, LUMC, Leiden, Netherlands; 4Pathology, LUMC, Leiden, Netherlands.

    MicroRNAs in urine are suitable targets for non-invasive detection of acute rejection (AR), since they represent relatively stable analytes. Indeed, we found that PCR signals…
  • 2016 American Transplant Congress

    Characteristics of Compatible Pair Participants in Living Donor Kidney Transplant Exchanges.

    F. Weng, T. Grogan, A. Patel, S. Mulgaonkar, M. Morgievich.

    Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.

    Introduction: Compatible pairs of living kidney donors and their intended recipients are being increasingly entered into living donor kidney transplant (LDKT) exchanges. The characteristics of…
  • 2016 American Transplant Congress

    Pre-Existing Chronic Heart Failure in Kidney Transplantation: An Underestimated Risk Factor for Graft Loss?

    F. Halleck, D. Khadzhynov, L. Lehner, E. Schrezenmeier, M. Duerr, A. Kleinsteuber, K. Budde, O. Staeck.

    Nephrology, Charité University, Berlin, Germany.

    BACKGROUND: Cardio-renal interactions influence graft and patient survival in kidney transplant recipients (KTR). There is only few data available analyzing pre-existing chronic heart failure (CHF)…
  • 2016 American Transplant Congress

    Autologous BK-Specific T-Cell Lines in Kidney Transplant Recipients.

    C. Lamarche,1,2,3 O. Julie,1,3 C. Carli,1,3 J.-S. Delisle.1,2,3

    1Centre de Recherche de l'Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada; 2Canadian National Transplant Research Program (CNTRP), Edmonton, Canada; 3ThéCell Network, Quebec, Canada.

    Background: More than 75% of the population has been exposed to BK polyomavirus and carries latent virus in the uroepithelium. Immunocompetent hosts are asymptomatic but…
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