Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Reduced Incidence and Level of De Novo Donor-Specific Antibodies in Belatacept-Treated vs. Cyclosporine-Treated Patients: Final Results from BENEFIT.
R. Bray,¹ H. Gebel,¹ R. Townsend,² M. Polinsky,² L. Yang,² U. Meier-Kriesche,² C. Larsen.¹
¹Emory University, Atlanta, GA; ²Bristol-Myers Squibb, Lawrenceville, NJ.
Background: The presence of donor-specific antibodies (DSA) has been associated with an increased risk of antibody-mediated rejection and graft failure. Mean fluorescence intensity (MFI) is…
2016 American Transplant Congress
Acute Rejection, New-Onset Diabetes After Transplant and Transplant Outcomes in Pediatric Kidney Recipients: Analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) Database.
A. Mehrnia, T. Le, T. Tamer, S. Bunnapradist.
Nephrology, UCLA, Los Angeles, CA.
Introduction Our objective was to identify the associations of new-onset diabetes after transplant (NODAT) and acute rejection (AR) in predicting patient mortality and transplant failure…
2016 American Transplant Congress
Impact of BKV Subtype Distribution on BKV Nephropathy, Viremia, and Renal Outcome in Patients After Renal Transplantation.
S. Anke,¹ L. Silvia,¹ H. Hermann,¹ H. Albert,² S. Corinna.²
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Virology, Hannover Medical School, Hannover, Germany.
Factors determining the course of BK viral (BKV) infection remain uncertain. We studied the role of BKV subtype distribution in BKV-infected patients after renal transplantation.-We…
2016 American Transplant Congress
Standard Dose Valganciclovir Prophylaxis for High-Risk Kidney Transplant Recipients Reduces Incidences of Breakthrough and Resistant Cytomegalovirus Infection.
Y. Huang, J. Park, A. Naik, D. Kaul.
University of Michigan, Ann Arbor, MI.
Background: Valganciclovir (VGCV) 900 mg/day is the standard dose (SD) for CMV prophylaxis in patients with CrCl > 60 ml/min, although some transplant centers use…
2016 American Transplant Congress
The Burden and Outcomes of Fractures in Kidney Transplant Recipients.
N. Atagu, T. Nguyen, N. Phan, O. Famure, Y. Li, J. Kim.
Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Background: Kidney transplantation confers an increased risk for bone fractures. However, there is poor consensus on the incidence of fractures in kidney transplant recipients (KTRs),…
2016 American Transplant Congress
Late Renal Allograft Rejection Is Predicted by High Intrapatient Variability of Tacrolimus Levels.
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.
IntroductionNonadherence to immunosuppressive medication is associated with rejection and graft loss. We have previously shown that intrapatient variability (IPV) of tacrolimus trough levels between 6-12…
2016 American Transplant Congress
Impact of the Kidney Allocation System with Deceased Donor Kidney Utilization at the DSA Level.
W. Ally,² C. Saunders,¹ K. Brayman,² A. Agarwal.²
¹Lifenet Health, Virginia Beach, VA; ²University of Virginia Health System, Charlottesville, VA.
Background: In December 2014, UNOS implemented broad sweeping changes in the new Kidney Allocation System (KAS). Recent summary reports by UNOS suggest that on a…
2016 American Transplant Congress
The Association of Life Expectancy by Resident Zip Code and Kidney Transplant Outcomes – What Is True Baseline Risk?
L. Buccini, D. Goldfarb, E. Poggio, S. Flechner, J. Schold.
Cleveland Clinic, Cleveland, OH.
Many factors beyond traditional clinical risk factors and demographics are associated with outcomes in the general population. These include behavioral, economic, genetic and environmental risks…
2016 American Transplant Congress
Morbid Obesity and Functional Status as Predictors of Surgical Complication After Renal Transplantation.
T. Veasey, J. Fleming, S. Strout, R. Miller, N. Pilch, H. Meadows, C. Mardis, B. Mardis, P. Baliga, J. McGillicuddy, D. Taber.
Medical University of South Carolina, Charleston, SC.
Purpose: Surgical complications after renal transplant may impact patient morbidity and healthcare utilization. Identification of patients at risk would allow for planning allocation of resources…
2016 American Transplant Congress
Impact of the New Kidney Allocation System (KAS) on Transplant Rates & Outcomes in Broadly-HLA Sensitized (HS) Patients Transplanted After Desensitization (DES).
A. Vo,¹ X. Zhang,² S. Williamson,¹ K. Myers,¹ N. Reinsmoen,² J. Choi,¹ J. Kahwaji,¹ A. Peng,¹ R. Villicana,¹ S. Jordan.¹
¹Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; ²HLA Laboratory, Cedars-Sinai Medical Center, LA, CA.
Introduction: HS patients not desensitized (DES) receiving transplants are at risk for ABMR. DES improves transplant rates, but is limited to donor availability. Implementation of…