ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    The Effect of Spironolactone on Calcineurininhibitor Induced Nephrotoxicity.

    L. Mortensen,1 H. Thiesson,1 C. Bistrup,1 F. Nielsen,3 U. Halekoh,2 B. Jensen,3 N. Marcussen.4

    1Department of Nephrology, Odense University Hospital, Odense, Denmark; 2Department of Biostatistics, University of Southern Denmark, Odense, Denmark; 3Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark; 4Department of Clinical Pathology, Odense University Hospital, Odense, Denmark.

    Purpose: Evidence points towards activation of the mineralocorticoid receptor (MR) to be involved in CNI nephrotoxicity. The SPIREN trial was designed to test the hypothesis…
  • 2016 American Transplant Congress

    Serum Inflammatory Biomarkers in Kidney Transplant Recipients and Renal Donors.

    J. Ramirez,1 E. Cuevas,1 J. Furuzawa,2 L. Morales-Buenrostro,3 M. Lopez-Cervantes,2 J. Alberu.1

    1Transplantation, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; 2Immunology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; 3Nephrology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; 4Medicine School, UNAM, Mexico City, Mexico.

    Kidney transplant recipients (KTR) have an increased risk for cardiovascular events, graft failure, and death. It is unknown whether serum inflammatory biomarkers correlate with eGFR…
  • 2016 American Transplant Congress

    Neighborhood Poverty and Gender Disparities in Access to Live Donor Kidney Transplantation.

    T. Purnell, X. Luo, S. Bae, L. Kucirka, D. Segev.

    Johns Hopkins, Baltimore.

    Women are less likely to receive a live donor kidney transplant (LDKT) than men, but little is known about the contribution of poverty to this…
  • 2016 American Transplant Congress

    Impact of HLA-DR Compatibility on Efficacy Outcomes and Renal Function in Kidney Transplant Recipients Following Early Switch from Calcineurin Inhibitor to Everolimus: Subanalysis from the ELEVATE Study.

    J. Cruzado, H. Holdaas, P. Lopez, J. Aguilar, G. Dong, F. Claas, W. Arns, M. van der Giet, J. de Fijter.

    ELEVATE study group, Llobregat Catalunya, Spain.

    Background: Human leukocyte antigen (HLA) compatibility between donor and recipient is considered an important factor for graft outcomes. Compatibility is associated with a lower incidence…
  • 2016 American Transplant Congress

    Clinical Outcomes of Simplified Once-Daily Immunosuppressive Regimen for Kidney Recipients.

    C.-K. Oh,1 S.-J. Kim,2 K. Huh,3 S. Kim,4 H. Cho,5 S. Lee.6

    1Surgery, Ajou University School of Medicine, Suwon, Republic of Korea; 2Surgery, Samsung Medical Center, Seoul, Republic of Korea; 3Surgery, Yonsei University Health System, Seoul, Republic of Korea; 4Surgery, CHA University School of Medicine, Pocheon, Republic of Korea; 5Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 6Surgery, Ajou University School of Medicine, Suwon, Republic of Korea.

    Background. Many of immunosuppressive drugs have been prescribed as twice-daily dosing. Simplified once-daily dosing of the entire drug regimen can enable patients to improve treatment…
  • 2016 American Transplant Congress

    Outcomes of Sequential and En Bloc Transplants in the Elderly: 10 Year Review of UNOS Data.

    V. Whittaker,1 R. Gruessner,1 A. Vikram,2 A. Gruessner.

    1Surgery, SUNY Upstate Medical University, Syracuse, NY; 2Medicine, SUNY Upstate Medical University, Syracuse, NY.

    To evaluate the outcome of sequential and en bloc transplants in the elderly.Method: Retrospective review UNOS data 2004-2014 kidney transplant alone patients >65 years. Patient…
  • 2016 American Transplant Congress

    Higher Functional Capacity Prior to Kidney Transplant Confers Lower Risk of New Onset Diabetes After Transplantation.

    I. Qaqish, S. Behmen, R. Heilman, H. Khamash, J. Huskey, S. Nair, H. Chakkera.

    Mayo Clinic, Phoenix, AZ.

    Background: New onset diabetes after transplantation (NODAT) adversely impacts both allograft function and patient survival. We hypothesize that higher functional capacity prior to kidney transplant…
  • 2016 American Transplant Congress

    Antibody Titers as Predictors of Kidney Graft Outcomes.

    A. Gilbert,1 M. Zaheer,1 O. Timofeeva,2 S. Rosen-Bronson,2 M. Awwad,2 D. Li,2 M. Grafals,1 B. Javaid,1 P. Abrams,1 J. Verbesey,1 M. Cooper.1

    1Surgery, MedStar Georgetown Transplant Institute, Washington, DC; 2Pathology, MedStar Georgetown Transplant Institute, Washington, DC.

    PURPOSE: Development of de novo donor specific antibody (dnDSA) following kidney transplantation is not uncommon. As laboratory techniques advance, rates of dnDSA have increased. However,…
  • 2016 American Transplant Congress

    Induction with T-cell Depletional Agents Is Safe and Efficacious in the Very Elderly Kidney Transplant Recipients: An Analysis of the OPTN Database.

    H. Dave, L. Wolfe, H. Fattah, D. Kumar, A. King, M. Levy, A. Cotterell, A. Sharma, C. Bhati, G. Gupta.

    Virginia Commonwealth University, Richmond, VA.

    Background: Kidney transplantation is increasingly being offered to the very elderly (Age>70 years) kidney transplant recipients. Previous studies analyzing the effect of induction immunosuppression in…
  • 2016 American Transplant Congress

    Fatty Liver in Non-Hepatic Organ Transplantation.

    N. Kemmer, A. Alsina.

    Tampa General Medical Group, Tampa, FL.

    With the availability of effective antiviral regimen for HCV, Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in western countries and…
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