ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Enhanced Activation of Hemostasis During Kidney Transplantation in Patients on Dialysis Compared to Pre-Emptively Transplanted Patients.

    T. van den berg, G. Nieuwenhuijs-Moeke, S. Bakker, R. Pol, T. Lisman.

    Groningen Transplant Center, University Medical Center Groningen, Groningen, Netherlands.

    Introduction: It is generally assumed that dialysis patients (DP) have a more severe bleeding diathesis related to platelet dysfunction than pre-emptively transplanted patients (PEP) who…
  • 2016 American Transplant Congress

    Distinct Phenotype and Function of Plasmacytoid Dendritic Cells from Kidney Allografts in Tolerant Recipients.

    N. Oh,1,2 C. Yang,1,2,3 M. Tonsho,1,2 D. Ndishabandi,1,2,3 P. Russell,1,2 R. Colvin,1,3 J. Madsen,1,2 A. Alessandrini.1,2

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA; 2Department of Surgery, Massachusetts General Hospital, Boston, MA; 3Department of Pathology, Massachusetts General Hospital, Boston, MA.

    BACKGROUND: Cellular infiltrates in kidney allografts may be relevant to the induction or maintenance of regulatory tolerance. Here we examined the phenotype, anatomical distribution and…
  • 2016 American Transplant Congress

    Circulating Angiotensin II Receptor: Possible Marker for Antibody Mediated Tissue Injury?

    P. Kimball, F. McDougan, G. Gupta.

    Transplant Surgery, VCU Health, Richmond, VA.

    Background. Antibody mediated rejection is the leading cause of renal allograft failure. Membrane-bound angiotensin II receptor(AngII) in the renal allograft can be a target of…
  • 2016 American Transplant Congress

    Polyclonal Treg Adoptive Therapy for Control of Subclinical Kidney Transplant Inflammation (TASK Pilot Trial).

    S. Chandran, Q. Tang, M. Sarwal, Z. Laszik, A. Putnam, T. Sigdel, E. Tavares, J. Bluestone, F. Vincenti.

    UCSF, San Francisco, CA.

    Purpose: Early renal graft inflammation is associated with progressive fibrosis & late dysfunction. Treg therapy can reverse established inflammation in animal models. We conducted a…
  • 2016 American Transplant Congress

    Short Term Changes in HRQOL Following Kidney Transplantation.

    I. Olorundare, H. Ying, M. McAdams-DeMarco, D. Segev.

    JHU, Baltimore.

    Health-Related Quality of Life (HRQOL) is a patient-centered outcome that measures the impact of a disease and its treatment. This is particularly relevant to those…
  • 2016 American Transplant Congress

    Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.

    C. Legendre,1 J. Campistol,2 T. Feldkamp,3 J. Wang,4 G. Remuzzi,5 L. Weekers,6 N. Sheerin.7

    1Université Paris Descartes & Hôpital Necker, Paris, France; 2Hospital Clinic, University of Barcelona, Barcelona, Spain; 3University Hospital Schleswig-Holstein, Kiel, Germany; 4Alexion Pharmaceuticals, Inc., Cheshire, CT; 5IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy; 6CHU de Liège, Liège, Belgium; 7Newcastle University, Newcastle upon Tyne, United Kingdom.

    Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…
  • 2016 American Transplant Congress

    De Novo Anti-HLA DSA Characteristics and Subclinical Antibody Mediated Kidney Allograft Injuries.

    T. Yamamoto, Y. Watarai, A. Takeda, M. Okada, M. Tsujita, T. Hiramitsu, N. Goto, S. Narumi, K. Morozumi, K. Uchida, T. Kobayashi.

    Nagoya daini red cross hospital, Nagoya, Japan.

    Background It has been reported that de novo donor-specific HLA antibody (dn DSA) production is associated with chronic antibody-mediated rejection (CAMR) which leads to poor…
  • 2016 American Transplant Congress

    A Non-Invasive Blood Transcriptional Assay, Ksort, Monitors Alloimmune Response in the Sailor Randomized Multicenter Trial.

    J. Ekberg,1 B. Jespersen,2 K. Skov,2 M. Sarwal,3 T. Sigdel,3 S. Hsieh,3 P. Lindner.1

    1Transplantation, Sahlgrenska University Hospital, Gothenburg, Sweden; 2Nephrology, Skejby Hospital, Aarhus, Denmark; 3Surgery, University of California, San Francisco.

    Non-invasive diagnosis and prediction of acute rejection (AR) is a critical unmet need. A In a randomized multicenter trial of 222 renal transplant recipients a…
  • 2016 American Transplant Congress

    A Kidney Paired Donation Standard Acquisition Charge Pilot Program.

    M. Rees,1 L. Reece,2 S. Rees,2 B. Crandall,2 A. Leichtman.4

    1UT, Toledo; 2APKD, Perrysburg; 3Arbor Res, Ann Arbor.

    Background/Purpose: A national non-profit Kidney Paired Dontion (KPD) organization undertook a demonstration project to redesign payment for KPD transplants with a payment model similar to…
  • 2016 American Transplant Congress

    Recovery of eGFR in Both Donors and Recipients After Living Donor Kidney Transplantation.

    J. Verbesey, A. Gilbert, A. Li, M. Reissmann, N. Foreman, M. Grafals, B. Javaid, P. Abrams, S. Ghasemian, M. Cooper.

    MedStar Georgetown Transplant Institute, Washington, DC.

    Purpose: LD kidney donation provides a much needed resource for patients with end stage renal disease. Providing adequate renal mass to the recipient (R) is…
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