Articles tagged "Kidney transplantation"

2016 American Transplant Congress
The Phenotypic Diversity of Late Silent Antibody-Mediated Rejection.
F. Eskandary,^1,2 J. Reeve,^1,3 H. Regele,⁴ L. Hidalgo,^1,3 D. Yoo,¹ N. Kozakowski,⁴ K. Famulski,¹ G. Böhmig,² P. Halloran.^1,5
¹Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada; ²Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ³Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; ⁴Department of Clinical Pathology, Medical University of Vienna, Vienna, Austria; ⁵Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, AB, Canada.
Study purpose: ABMR is a driving force of long-term allograft loss in organ transplantation. The present study was designed to characterize the phenotypic diversity of…
2016 American Transplant Congress
Long Term Outcomes Following Antibody Mediated Rejection (AMR) in Renal Transplant Recipients.
R. Crew, S. Patel, H. Morris, M. Chiles, L. Ratner.
Columbia University, New York.
INTRO: Progress in AMR treatment has improved early graft survival. Since the new kidney allocation system results in more sensitized patients getting transplanted, we expect…
2016 American Transplant Congress
The Epidemiology of Clostridium difficile Infection in a National Kidney Transplant Center.
C. Kennedy,¹ C. Waldron,¹ M. Scally,² K. Burns,² C. Magee,¹ F. Fitzpatrick.²
¹Department of Nephrology, Beaumont Hospital, Dublin, Ireland; ²Department of Microbiology, Beaumont Hospital, Dublin, Ireland.
BackgroundKidney transplant recipients (KTRs) are at increased risk of Clostridium difficile infection (CDI). We aimed to retrospectively describe the epidemiology of CDI in a national…
2016 American Transplant Congress
Conversion to Belatacept as Rescue Therapy in Kidney Transplant Recipients with Severe Graft Dysfunction.
F. Oldhafer,¹ M. Hiss,² A. Schwarz,² H. Haller,² G. Einecke.²
¹Clinic for General, Abdominal and Transplant Surgery, Hannover Medical School, Hannover, Germany; ²Clinic for Nephrology, Hannover Medical School, Hannover, Germany.
Belatacept is a fusion protein that prevents T cell co-stimulation via the CD28 receptor. If used as first-line therapy, immunosuppression with Belatacept is associated with…
2016 American Transplant Congress
Donor-Specific Antibodies in a Single-Center Pediatric Kidney Transplant Population – Incidence and Risk Factors.
M. Bock,¹ L. Starkey,¹ C. Buchanan,² E. Steinberg,² A. Sikora,² K. McKinnon,² M. Wachs,² J. Goebel.¹
¹Transplant Surgery, Children's Hospital Colorado, Aurora, CO; ²Pediatric Nephrology, Children's Hospital Colorado, Aurora, CO.
In mid-2015, we implemented donor-specific antibody (DSA) monitoring in our pediatric kidney transplant recipient (pKTR) population as recommended (Transplantation 2013;95:19-). We now cross-sectionally analyzed our…
2016 American Transplant Congress
Incidence of Polyoma Virus Associated Nephropathy in a Single Transplant Center Employing a Reduction of Immunosuppression at a Lower Threshold of BK Viremia.
M. Azar, A. Valika, D. Banach, I. Hall, M. Malinis.
Internal Medicine, Infectious Diseases, Yale University, New Haven, CT.
BackgroundPolyoma virus associated nephropathy (PyVAN) caused by BK virus (BKV) is a major complication occurring in 1-10% of renal transplant recipients. Screening and reduction of…
2016 American Transplant Congress
Risk Factors for Single and Recurrent Symptomatic Urinary Tract Infections within the First Year After Kidney Transplantation.
K. Bourgi, W. Choi, A. Nakhle, Z. Abdel-Rahman, O. Abreu-Lanfranco, M. Ramesh, A. Patel, R. Del Busto, G. Alangaden.
Henry Ford Hospital, Detroit, MI.
Urinary Tract Infection (UTI) is the most common infection after kidney transplantation (KT). However studies have been incongruent regarding risk factors associated with incidence and…
2016 American Transplant Congress
Clinical Significance of Mycophenolic Acid Therapeutic Drug Monitoring in Kidney Transplant Recipients.
C.-D. Kim, J.-H. Cho, K. Kim, M. Kim, W. Do, Y. Yang, T. Yim, I. Hwang, J.-H. Lee, H.-Y. Jung, J.-Y. Choi, S.-H. Park, Y.-L. Kim.
Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
Background: Mycophenolic acid (MPA) is a widely used immunosuppressant to prevent acute rejection in kidney transplant recipients (KTRs). However, clinical significance of MPA therapeutic drug…
2016 American Transplant Congress
Kidney Transplant Recipient Adherence Measured by Proportion of Days Covered Is Associated with Late Biopsy Proven Acute Rejection.
B. Hofmeyer, K. Look, J. Fose, A. Pulvermacher, A. Djamali, D. Hager.
UW Health, Madison, WI.
While medication non-adherence is a known risk factor for late “biopsy proven acute rejection (BPAR),” the Pharmacy Quality Alliance definition of “proportion of days covered…
2016 American Transplant Congress
Potential Applications of Viral miRNA Assays in the Management of Transplant Patients with Polyomavirus BK Infection.
P. Randhawa, G. Zeng, Y. Huang.
Department of Pathology, The Thomas E Starzl Transplant Institute, University of Pittsburgh, Pittsburgh, PA.
Background: BKV encodes two miRNAs from a single precursor: BKV-miR-B1-5p & BKV-JCV-miR-BJ1-3p. These viral miRNAs direct cleavage of large T antigen mRNAs, downregulate viral T…