Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Kidney Transplantation with Strong Preformed Donor-Specific Antibodies: Impact of C1q-Binding Ability.
J. Malheiro,¹ S. Tafulo,² S. Santos,¹ M. Costa,¹ L. Martins,¹ L. Dias,¹ A. Henriques.¹
¹Nephrology, CHP, Porto, Portugal; ²CSTP, Porto, Portugal.
HLA-incompatible kidney transplantation is associated with worse outcomes given the presence of donor-specific anti-HLA antibodies (DSA). Our aim was to investigate the association between preformed…
2016 American Transplant Congress
Rapid Detection of Acute Infection in Immunosuppressed Renal Patients with IRIDICA: A Pilot Study.
S. Hassan,¹ A. Adwaney,¹ A. Massiah,² R. Murphy,² S. Law,¹ S. Mohd-Afzal,¹ M. Wilks,² R. Thuraisingham.¹
¹Renal, Royal London Hospital, Barts Health Trust, London, United Kingdom; ²Microbiology, Barts Health Trust, London, United Kingdom.
BackgroundThe Abbott IRIDICA bacterial bloodstream (BAC BSI) assay is a rapid semi-quantitative diagnostic test that is able to detect over 800 significant pathogens using PCR…
2016 American Transplant Congress
Genomic-Derived Markers to Identify Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.
E. Rhone,¹ R. Gehrau,² S. Bontha,² P. Walker,³ C. Dumur,⁴ D. Maluf,² V. Mas.²
¹Pediatrics, University of Virginia, Charlottesville, VA; ²Surgery, University of Virginia, Charlottesville, VA; ³Nephropath, Little Rock, AR; ⁴Pathology, Virginia Commonwealth University, Richmond, VA.
Background:Calcineurin inhibitor nephrotoxicity (CNIT) is a well-known contributor to chronic allograft dysfunction in kidney transplant recipients (KTRs). Pediatric KTRs are particularly at risk given their…
2016 American Transplant Congress
Renal Outcomes of Pediatric Kidney Transplant Recipients Following a Previous Solid Organ Transplantation.
G. Hamdani,¹ B. Zhang,² J. Goebel,³ E. Nehus.¹
¹Division of Nephrology & Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ²Center for Epidemiology & Biostatistics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; ³Nephrology, Children's Hospital Colorado, Aurora, CO.
Purpose: We aimed to study the renal outcomes of pediatric kidney transplant recipients following a previous non-renal solid organ transplantation (SOT).Methods: A retrospective analysis of…
2016 American Transplant Congress
Slipping Through the Cracks: Late Onset BK Viremia.
J. Gandhi,¹ M. Mackenzie,¹ D. DeWolfe,² F. Cardarelli,³ M. Pavlakis,³ C. Tan.^1,4
¹Center for Virology & Vaccine Research, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; ²Division of Nephrology, BIDMC, Boston, MA; ³The Transplant Institute, BIDMC, Boston, MA; ⁴Division of Infectious Disease, BIDMC, Boston, MA.
Introduction: Most studies indicate that viremia caused by BK virus (BKV), the step preceding BKV associated nephropathy (BKVN) in kidney transplant recipients (KTRs), occurs within…
2016 American Transplant Congress
Tacrolimus Precision Medicine: Antibiotics Increase Intra-Patient Variability in Tacrolimus Trough Concentrations in Kidney Transplant Recipients.
Y. Zheng, J. Lee, A. Masand, D. Dadhania, M. Thangamani, M. Suthanthiran.
Medicine/Nephrology and Hyeprtension, Weill Cornell Medical College, New York, NY.
BACKGROUND. The gut microbiome impacts drug absorption, metabolism, and distribution and was recently shown to be associated with tacrolimus dosing requirements. Since antibiotics can alter…
2016 American Transplant Congress
Post-Transplantation Hypomagnesemia as a Predictor of Survival Among the Kidney Transplant Population.
T. Hod, B. Patibandla, A. Chandraker.
Transplant Research Center, Brigham and women's hospital, Boston, MA.
We have previously shown a robust relationship between low magnesium in the first year post-transplant and better long-term kidney allograft function. Given this somewhat counterintuitive…
2016 American Transplant Congress
Psychosocial Factors Associated with Medication Adherence Based on Self Reports in Kidney Allograft Recipients: Baseline Findings from the PRIMA (ImPRoving Adherence to Immunosuppressive Therapy by Mobile Internet Application) Study.
A. Han,¹ C. Choi,¹ S.-Y. Kim,¹ S. Cho,¹ M.-J. Cho,¹ C. Lee,¹ S. Ahn,¹ S.-I. Min,¹ S.-K. Min,¹ I. Jung,¹ S. Kim,² M. Park,³ J. Ha.^1,3
¹Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Department of Surgery, Myongji Hospital, Goyang-si, Gyeonggi-do, Republic of Korea; ³Korean Organ Donation Agency, Seoul, Republic of Korea.
Background. We have assessed the prevalence of medication nonadherence after kidney transplantation and investigated its psychosocial correlates, as a part of the PRIMA study, an…
2016 American Transplant Congress
Kidney Waitlist Management with Lean Six Sigma.
V. Arelin,¹ J. Schaefer,³ H. Haller,¹ I. Ackermann,² H. Schrem.²
¹Nephrology and Hypertension, Medical School Hanover, Hannover, Germany; ²Transplant and Viceral Surgery, Medical School Hanover, Hannover, Germany; ³Center for Information Technology, Medical School Hanover, Hannover, Germany.
BackgroundLean thinking is a bundle of concepts, methods and tools for organizing human activities in organizations. It attempts to eliminate the underlying unnecessary waste in…
2016 American Transplant Congress
Predictors of Patient Uncertainty Regarding Treatment Options Among End Stage Renal Disease Patients Evaluated for Kidney Transplantation.
L. McPherson,¹ M. Basu,¹ S. Pastan,¹ S. Mohan,² M. Wolf,³ J. Gander,¹ R. Patzer.¹
¹Emory University, Atlanta, GA; ²Columbia University, New York City, NY; ³Northwestern University, Chicago, IL.
Background: Although kidney transplantation (KTx) provides a significant survival benefit over long-term dialysis, many end stage renal disease (ESRD) patients are uncertain or conflicted about…