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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Patients with ESRD Due to Diabetes Have Higher Variability of Their Tacrolimus Levels and Worse Outcomes.

    D. Goodall, M. Willicombe, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.

    IntroductionNonadherence to immunosuppressants is associated with rejection and graft loss and nonadherence to antidiabetics is associated with poor glycaemic control leading to microvascular complications and…
  • 2016 American Transplant Congress

    Predicting the Ability of Anti-HLA Antibodies to Activate Complement.

    D. Bekbolsynov, C. Baum, B. Mierzejewska, A. Malebari, M. Rees, S. Stepkowski.

    University of Toledo, Toledo.

    Purpose: The single antigen bead (SAB) assay measures binding of antibodies (Abs) to HLA in units of mean florescence intensity (MFI). Two assays measure the…
  • 2016 American Transplant Congress

    Graft Survival in Sensitized and Non-Sensitized Patients: Role of the Combination of Donor-Specific Antibodies and Acute Rejection.

    P. Souza,1 A. Aguirre,1 G. Bezerra,2 H. Rodrigues,2 F. Agena,1 D. David,1 F. de Paula,1 E. David-Neto,1 M. Castro.1

    1Renal Transplant Service, Hospital das Clínicas de São Paulo, Sao Paulo, Brazil; 2Immunology Laboratory, Instituto do Coração (InCor), Sao Paulo, Brazil.

    Background: Sensitized (S) patients have higher risk for acute rejection (AR), especially ABMR. DSA is a risk fator for ABMR, however, its impact on AR…
  • 2016 American Transplant Congress

    Outcomes of Untreated Asymptomatic Bacteriuria in Renal Transplant Recipients: A Single-Center Experience.

    W. Davis, R.-A. Lee, L. Daniels, S. Todd, K. True, P. Chong.

    University of North Carolina Medical Center, Chapel Hill, NC.

    Background. Renal transplant recipients (RTR) with asymptomatic bacteriuria (AB) are often treated with antibiotics. This could lead to complications related to antibiotic treatment including Clostridium…
  • 2016 American Transplant Congress

    A Change in Insulin Sensitivity and Lipid Profile in Renal Transplant Recipients Converted from Cyclosporine or Standard Release Tacrolimus to Once-Daily Prolonged Release Tacrolimus.

    Y. Jung,1 Y. Kim,1 S. Kim,1 H. Shin,1 H. Rim,1 H. Rhew.2

    1Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea; 2Urology, Kosin University College of Medicine, Busan, Republic of Korea.

    Background : New-onset diabetes after transplantation may be associated with the use of tacrolimus (Tac) causing impaired insulin release or reduced insulin sensitivity. And, dyslipidemia…
  • 2016 American Transplant Congress

    Low Pretransplant BMI/Weight and Changes in Posttransplant T Cell Exhaustion Levels Are Associated with Viremia/Viral Infection in Pediatric Kidney Transplantation in the First Post-Transplant Year – A Report from the IMPACT Study Consortium.

    R. Ettenger,1 H. Chin,2 P. Grimm,3 K. Kesler,2 E. Reed,4 M. Sarwal,5 B. Warshaw,6 E. Tsai,1 A. Kirk.7

    1Pediatrics, UCLA, LA, CA; 2Rho, Chappel Hill, NC; 3Pediatrics, Stanford Univ, Palo Alto, CA; 4Pathology, UCLA, LA, CA; 5Surgery, UCSF School of Medicien, SF, CA; 6Pediatric Nephrolgoy, Children's Healthcare of Atlanta, Atlanta, GA; 7Surgery, Duke University, Durham, NC.

    Viral consequences of immunosuppression (IS) in pediatric(ped)kidney(kid)transplantation(Tx)patients(pts) are not fully known. We prospectively examined the immunologic and infectious (inf) history of 106 ped Tx pts…
  • 2016 American Transplant Congress

    Urinary CXCL9 Protein as Biomarker for BK Polyoma Viremia.

    N. Sarabu,1 R. El-Rifai,2 J. Augustine,1 A. Padiyar,1 A. Huml,1 T. Young,1 V. Rodriguez,1 D. Hricik.1

    1Division of Nephrology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH; 2Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Introduction: BK infection is common in kidney transplant patients and can result in accelerated loss of allografts. Management involves empiric lowering of immunosuppression, which can…
  • 2016 American Transplant Congress

    Clinical Measures to Reduce Early Urinary Tract Infections Following Kidney Transplantation: A Single Center Experience.

    B. Chopra, T. Ko, C. Webster, J. Sheyman, A. Arumgarajah, V. Katragadda, R. Marcus, K. Sureshkumar.

    Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.

    Urinary Tract infection (UTI) following kidney transplantation (KTx) is associated with increased morbidity. We implemented simple clinical measures in an attempt to reduce UTI incidence…
  • 2016 American Transplant Congress

    What if Mycophenolic Acid Product Is Discontinued Less Than 6 Weeks Before Pregnancy?

    N. Sifontis,1 L. Coscia,2 D. Armenti,2 S. Constantinescu,2,3 M. Moritz.2,4

    1Pharmacy Practice, Temple University, Philadelphia, PA; 2Gift of Life Institute, National Transplantation Pregnancy Registry (NTPR), Philadelphia, PA; 3Medicine, Temple University, Philadelphia, PA; 4Surgery, Lehigh Valley Health Network, Allentown, PA.

    It is recommended that mycophenolic acid (MPA) products be discontinued at least 6 wks prior to conceiving due to potential teratogenic effects and increase risk…
  • 2016 American Transplant Congress

    Ischemia-Reperfusion Injury Following Transplantation: Implications for the Modulation of CXCL8 Chemokine Function.

    B. Martinez Burgo,1 S. Ali,1 J. Kirby,1 N. Sheerin,1 S. Cobb,2 D. Kashanin.3

    1Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom; 2Chemistry Department, Durham University, Durham, United Kingdom; 3Cellix Ltd., Dublin, Ireland.

    Ischemia-Reperfusion Injury (IRI) is a major contributor to subsequent graft dysfunction. Chemokines play a key role in leukocyte recruitment towards to the injured tissue. CXCL8…
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