2017 American Transplant Congress
Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.
1University Health Network, Toronto, ON, Canada; 2Sinai Health System, Toronto, ON, Canada
IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…2017 American Transplant Congress
Belatacept After Kidney Transplantation in Adolescents.
Pediatric Nephrology, Hannover Medical School, Hannover, Germany
Background: Regardless of recipient age at kidney transplantation (KTx), patients are at greatest risk for graft loss in adolescence. This is in part due to…2017 American Transplant Congress
Outcomes with Steroid Avoidance Regimen After Kidney Transplantation without Induction Immunosuppression.
INTRODUCTION: Use of induction immunosuppression therapy at the time of kidney transplantation is variable in low immunological risk kidney transplant recipients. Though acceptable allograft outcomes…2017 American Transplant Congress
IL-21R Antagonist Inhibits Differentiation of B Cells Towards Plasmablasts upon Alloantigen Stimulation.
Background: Antigen-specific antibody responses rely on IL-21+ T follicular helper (Tfh) cells that regulate B cell differentiation. In transplantation, a large proportion of renal allograft…2017 American Transplant Congress
Determinants of Severe Interstitial Fibrosis in Kidney Allografts: Major Impact of Circulating Donor-Specific Anti-HLA Antibodies.
Paris Translational Research Center for Organ Transplantation, Paris, France
Interstitial fibrosis represents a major cause of kidney allograft failure. We investigated the independent contribution of circulating donor-specific anti-HLA antibodies (DSA) in the development of…2017 American Transplant Congress
Chronic Antibody Mediated Rejection (cABMR) in ABO-Incompatible and ABO-Compatible Kidney Transplants: A Single US Center Experience.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Introduction:Similar patient and graft outcomes have been previously reported for ABO compatible (ABOc) and ABO incompatible (ABOi) kidney transplants. However, data are limited on the…2017 American Transplant Congress
Mycophenolate Dose Reductions Are Not Associated with De Novo Donor-Specific Antibodies.
University of Colorado, Aurora, CO
De novo donor-specific antibodies (dnDSA) are central to the development of antibody-mediated rejection, which is the most important cause of death-censored graft loss. It is…2017 American Transplant Congress
Program-Specific Offer Acceptance Behavior for Kidney Programs Across the Spectrum of KDPI.
Scientific Registry of Transplant Recipients, Minneapolis, MN
Little is known about the offer acceptance behavior of kidney transplant programs, which affects rates of discard and access to transplant. An offer acceptance model…2017 American Transplant Congress
Estimating Donor Organ Quality with Baseline Histology and Kidney Donor Risk Index for Predicting Graft Outcomes in Deceased Donor Kidney Transplantation.
Background: Donor organ quality is a key determinant of graft outcomes in deceased donor kidney transplantation (DDKT). The effect of baseline histology at the time…2017 American Transplant Congress
Novel Therapies for Diabetic Kidney Disease.
University of California, San Francisco, San Francisco, CA
Introduction: The development and progression of diabetic kidney disease (DKD) is thought to involve a combination of hemodynamic, metabolic, ischemic, and inflammatory factors; however, the…
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