Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Population Pharmacokinetic Profiling of Tacrolimus in Renal Transplant Recipients (RTRs) Taking Diltiazem.
P. Trevillian,^1,2,3 M. Heer,^1,2 S. Ainsworth,¹ A. Hibberd.^1,2,3
¹Newcastle Transplant Unit, John Hunter Hospital, Newcastle, NSW, Australia; ²University of Newcastle, Newcastle, NSW, Australia; ³Hunter Transplant Research Foundation, Hunter Medical Research Institute, Newcastle, NSW, Australia
Background: Over the past 6 years we have prospectively used pharmacokinetic (PK) profiling of Tacrolimus (TAC) in “stable” RTR's to individualise future dosing. This study…
2017 American Transplant Congress
Efficacy of Calcineurin Inhibitors Transferring to Rapamycin in Live Kidney Transplantation from Old Donors to Young Recipients.
G. Chen, C. Wang, Z. Wu, C. Wang, J. Qiu, L. Chen.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Background Calcineurin inhibitor(CNI) nephrotoxicity is one of the major reasons for chronic allograft injury in live kidney transplantation from old donors to young recipients. Therefore…
2017 American Transplant Congress
Post-Transplant Graft Function Is Associated with Major Cardiovascular Events in Kidney Transplant Recipients: A Multicenter Cohort Study.
J. Park,¹ Y. Kim,² S. Yang,³ S. Park,² S.-K. Park,⁴ D. Han,⁵ Y. Kim,² Y. Kim,⁵ J. Lee.⁶
¹Department of Internal Medicine, Dongguk University Ilsan Hospital, Gyeonggi-do, Korea; ²Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; ⁴Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁵Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁶Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea
Background: Reduced kidney function is an independent risk factor for cardiovascular disease in the general population. However, the association between post-transplantation graft function and subsequent…
2017 American Transplant Congress
The Clinical Significance of Red Cell Distribution Width (RDW) in Kidney Transplant Recipients.
S. Park,¹ J. Ha,¹ Y. Kim,¹ H. Lee,¹ Y. Kim,¹ C. Lim,¹ I. Jung,¹ D.-J. Han,² S.-K. Park,² Y. Kim,² J. Lee.¹
¹Seoul National University College of Medicine, Seoul, Korea; ²Asan Medican Center, Seoul, Korea
Background Increased red cell distribution width (RDW) has been known to be associated with worse prognosis in various populations. Although the levels of RDW are…
2017 American Transplant Congress
Impact of a Pharmacist-Led Vaccine Recommendation Program for Pediatric Kidney Transplant Candidates.
C. Carthon,¹ R. Hall,² P. Maxwell,² B. Crowther.²
¹Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; ²University Transplant Center, University Health System, San Antonio, TX
Pediatric transplant recipients commonly have a deficient immunization status at the time of transplantation. Utilizing transplant pharmacists to improve these immunization rates has not previously…
2017 American Transplant Congress
Challenges for the Travelling Donor: Variability Between Donor Work-Up and Donor Surgery in the Canadian Kidney Paired Donation Program.
B. Reikie, T. Kroczak, T. McGregor.
Surgery, University of Manitoba, Winnipeg, MB, Canada; Surgery, University of Toronto, Toronto, ON, Canada; Urology, Queen's University, Kingston, ON, Canada
Background: A primary obstacle to providing renal transplantation is limited access to donated kidneys. The living donor pool for renal allografts was greatly expanded through…
2017 American Transplant Congress
Seasonality of Mortality and Graft Failure Among Kidney Transplant Recipients in the US.
B. Astor,¹ M. Melamed,² D. Mandelbrot,¹ A. Djamali.¹
¹University of Wisconsin School of Medicine and Public Health, Madison, WI; ²Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY
The incidence of mortality in the general population is significantly higher in winter than in summer. It is unknown whether such a seasonal difference exists…
2017 American Transplant Congress
Use of Modified Geriatric Assessment in Evaluation of Older Adults for Kidney Transplant Suitability.
K. Campbell,¹ F. Enger, E. Patrick,² M. Saunders,³ M. Josephson,¹ Y. Becker.²
¹Medicine, University of Chicago, Chicago, IL; ²Kidney Transplant, University of Chicago, Chicago, IL; ³Hospital Medicine, University of Chicago, Chicago, IL
BackgroundThere is an increasing incidence and prevalence of older adults with ESRD. Per guideline recommendations, many of these patients are now being considered for kidney…
2017 American Transplant Congress
Biological Interplay Between Circulating HLA-sp Alloreactive Memory B-Cells and Long-Lived Plasma Cells in Kidney Transplant Patients Undergoing Chronic ABMR.
S. Luque,² M. Lúcia,⁴ M. Jarque,² E. Crespo,² E. Melilli,¹ J. Martorell,³ J. Cruzado,^1,2 J. Torras,^1,2 J. Grinyó,^1,2 O. Bestard.^1,2
¹Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, Spain; ²Experimental Nephrology Laboratory, IDIBELL, Barcelona, Spain; ³Immunogenetics Laboratory, Hospital Clínic, Barcelona, Spain; ⁴Transplant Immunology, School of Medicine, Stanford
Alloreactive humoral responses are one of the main causes of immune-mediated allograft injury in kidney transplantation. Different biological compartments are involved in the generation and…
2017 American Transplant Congress
Shared Epitopes Contribute to Accumulation of Highly Sensitized Patients in Kidney Paired Donation Program.
S. Stepkowski, B. Mierzejewska, C. Baum, D. Bekbolsynov, R. Brunner, J. Kopke, S. Rees, M. Rees.
University of Toledo, Toledo, OH
Introduction: Kidney Paired Donation (KPD) programs suffer from the accumulation of highly sensitized patients. We evaluated the sensitization patterns in our KPD program-by comparison of…