Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Impact of Race on Selection of the Living Donor Candidate.
D. Bohorquez, A. Thomasson, P. Porrett.
Surgery, University of Pennsylvania, Philadelphia, PA
Background It has been reported that African-Americans (AA) living kidney donors have an increased risk of ESRD versus non-Hispanic whites (NHW). To date, it is…
2017 American Transplant Congress
Immediate vs Delayed Initiation of CMV Prophylaxis…Safe and Cost Beneficial?
L. Cotiguala, A. Carlson, C. Truax, B. Sirandas, I. Hall, L. Smith.
University of Utah Health Care, Salt Lake City, UT
Background: Recommendations differ on when to initiate valganciclovir (VGCV) for CMV prophylaxis (ppx) after tx. Current labeling states within 10 days of tx. We evaluated…
2017 American Transplant Congress
RAS Inhibition Attenuates Urine Angiotensin II-Regulated Proteins Associated with Interstitial Fibrosis and Tubular Atrophy in Kidney Transplant Recipients.
Z. Mohammed-Ali,¹ S. Reid,³ P. Yip,¹ H. Cardinal,² M.-J. Hébert,² Y. Li,⁴ S. Kim,^1,3,4 A. Konvalinka.^1,3
¹University Health Network, Toronto, ON, Canada; ²Centre de Recherche du Centre Hospitalier de l'Université de Montréal - CRCHUM, Montréal, QC, Canada; ³Institute of Medical Science, University of Toronto, Toronto, ON, Canada; ⁴Institute of Health Policy, University of Toronto, Toronto, ON, Canada
Angiotensin-II (AngII), the main effector of the renin-angiotensin system (RAS), can lead to interstitial fibrosis/ tubular atrophy (IFTA) in kidney transplant recipients, mainly through AT-1R…
2017 American Transplant Congress
Pre-Transplant Non-Cytotoxic Donor Specific HLA Antibodies Do Not Increase the Risk of Graft Dysfunction in Kidney Transplant Recipients with Thymoglobulin and IVIG Induction.
A. Colovai, M. Ajaimi, N. Hayde, L. Kamal, S. Chan, C. Savchik, J. Rocca, E. Akalin.
Surgery, Montefiore Medical Center, Bronx, NY
The aim of this study was to evaluate the impact of pre-formed donor specific HLA antibodies (DSA) in a large population of kidney transplant (tx)…
2017 American Transplant Congress
Extended Ex Vivo Kidney Perfusion Using Hemopure as an Oxygen Carrier: A Method to Preserve, Assess and Repair Discarded Organs.
F. Fontan, M. Aburawi, N. Karimian, K. Uygun, F. Delmonico, H. Yeh, J. Markmann.
Transplant Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background: Hypothermic non-oxygenated machine perfusion (HMP) is commonly used in kidney preservation, providing some advantage over static cold storage, as well as flow and resistance…
2017 American Transplant Congress
Recurrent Lupus Nephritis in a Multi-Ethnic Kidney Transplant Population.
I. Tang,¹ A. Koganti,¹ S. Setty,² S. Akkina.³
¹Medicine, University of Illinois at Chicago, Chicago, IL; ²Pahology, University of Illinois at Chicago, Chicago, IL; ³Medicine, Loyola University, Chicago, IL
The incidence of recurrent lupus nephritis varies among different ethnic groups. We performed a single center retrospective analysis of recurrent lupus nephritis in kidney transplant…
2017 American Transplant Congress
Optimal Induction Therapy for Kidney Transplantation in Previous Heart Transplant Recipients: Analysis of OPTN/UNOS Registry.
M. Sampaio, S. Hussain, B. Chopra, K. Sureshkumar.
Nephrology, Internal Medicine, Allegheny General Hospital, Pittsburgh, PA
It is unclear as to which induction agent is optimal for kidney transplant (KT) in prior heart transplant (HT) recipients who are already immunocompromised from…
2017 American Transplant Congress
Blood Tfh Cells Exhibit Impaired B Cell Help in Operationally Tolerant Patients.
R. Danger,¹ A. Chenouard,¹ M. Chesneau,¹ S. Castagnet,² P. Guérif,¹ N. Degauque,¹ M. Giral,¹ S. Brouard.¹
¹Inserm UMR 1064, Nantes University Hospital, Nantes, France; ²HLA Laboratory, Etablissement Français du Sang, Nantes, France
Introduction: Operationally tolerant (TOL) patients display a defect of B cell differentiation, with a deficiency in circulating plasma cells secreting antibodies, which could partly contribute…
2017 American Transplant Congress
Use of Pulsatile Perfusion Modifies the Effect of Delayed Graft Function on Graft Failure.
A. Thomas, A. Shaffer, A. Massie, D. Segev.
JHU, Baltimore
While the causal mechanisms remain elusive, delayed graft function (DGF) has been associated with graft failure in recipients of deceased-donor kidneys. Pulsatile perfusion pump use…
2017 American Transplant Congress
Engaging Clinicians and Patients Regarding Frailty Assessment in Kidney Transplant Candidates.
S. Rasmussen, J. Konel, H. Ying, C. Haugen, E. King, S. DiBrito, D. Segev, M. McAdams DeMarco.
JHU, Baltimore
Background: The Fried frailty phenotype, a measure of physiologic reserve, is associated with poor kidney transplant (KT) outcomes. However, it was developed in community-dwelling older…