Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Kidney Recipients with 10 Year Belatacept-Treatment Display an Altered T Cell Subset Composition and Low Plasma Cytokine Levels Compared to Matched Patients with CNI-Based Immunosuppression.
C. Falk,¹ C. Neudörfl,¹ A. Scherf,¹ K. Daemen,¹ J. Keil,¹ J. Klempnauer,² F. Lehner,² G. Grannas.²
¹Institute of Transplant Immunology, IFB-Tx, MHH, Hannover, Germany; ²Department of Abdominal, Visceral and Transplantation Surgery, MHH, Hannover, Germany
Introduction/BackgroundMore than 10 years ago, Belatacept (Bela)-based immunosuppression was investigated in the BENEFIT trial of kidney transplantation (KTx) compared to CNI-based immunosuppression. Bela inhibits T…
2017 American Transplant Congress
Characterization of De Novo Donor-Specific HLA Antibodies and Correlations with C4d+ Antibody-Mediated Rejection of Kidney Transplants.
R. Rajalingam,¹ D. Kopchaliiska,¹ O. Buenaventura,¹ M. Singh,² S. Tomlanovich.²
¹Immunogenetics and Transplantation Laboratory, Depart. of Surgery, University of California San Francisco, San Francisco, CA; ²Transplant Service, Department of Medicine, University of California San Francisc, San Francisco, CA
Aim: Characteristics of de novo donor-specific HLA antibodies (dnDSA) that are associated with C4d positive antibody-mediated rejection (C4d+ AMR) in kidney transplants have not been…
2017 American Transplant Congress
Effect of Blood Pressure Just Before Release of the Vascular Clamps on the Renal Function of Kidney Transplantation Recipients: A Retrospective Study.
K. Tsujimura,¹ M. Ota,¹ H. Ishida,² K. Tanabe.²
¹Surgery, Tomishiro Central Hospital, Tomishiro-shi, Okinawa, Japan; ²Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
OBJECTIVE: To assess the effect of blood pressure just before release of the vascular clamps on the renal function of kidney transplantation (KTx) recipients.METHODS: We…
2017 American Transplant Congress
Long-Term Immunosuppression Adherence After Kidney Transplant and Relationship to Allograft Histology.
E. Lorenz, B. Smith, F. Cosio, N. Shah, P. Groehler, J. Verdick, W. Park, M. Stegall.
Mayo Clinic, Rochester
Background: Loss of Medicare coverage for immunosuppression 3 years after kidney transplant may be associated with increased nonadherence. The goal of this study was to…
2017 American Transplant Congress
Induction Immunotherapy in ECD and DGF Kidneys: Does ECD Equal Diminishing Induction Returns?
M. Barrett, A. Smith, K. Woodside, R. Sung.
University of Michigan, Ann Arbor
The benefit of induction immunotherapy to prevent DGF or mitigate its effects in recipients of marginal kidneys is not well understood and practices vary. We…
2017 American Transplant Congress
Positive Flow Crossmatch After Negative Virtual Crossmatch -A Single Center Experience.
Q. Xu, S. Leckie.
Pathology and Lab Medicine, London Health Sciences Center, London, ON, Canada
Aims: To determine causes of Flow Cytometry crossmatch (FCXM) after a negative virtual crossmatch (VirXM), even with sensitive solid-phase antibody assay and complete HLA typings…
2017 American Transplant Congress
Awareness of Change in the Kidney Allocation System Among Dialysis Providers from Facilities with Low Waitlisting.
M. Basu,¹ K. Smith,¹ S. Pastan,¹ L. Plantinga,^1,2 S. Mohan,³ C. Escoffery,² J. Chung,¹ T. Melanson,² R. Patzer.^1,2
¹Emory University School of Medicine, Atlanta, GA; ²Rollins School of Public Health, Atlanta, GA; ³Columbia University, New York, NY
Background: In December 2014, the new kidney allocation system (KAS) was implemented and is expected to particularly benefit patients who have spent an extended time…
2017 American Transplant Congress
HLA Alloimmunization According to the Different Immunization Events and Consequences on Access to Kidney Transplantation.
V. Pernin,¹ A. Cros,¹ I. Szwarc,¹ C. Rene,² J.-F. Eliaou,² V. Garrigue,¹ G. Mourad,¹ M. Le Quintrec-Donnette.¹
¹Department Nephrology and Transplantation, CHU Lapeyronie, Montpellier, France; ²Department of Immunology, CHU St ELoi, Montpellier, France
Patients awaiting solid organ transplantation may develop anti-HLA antibodies after sensitization events such as transfusions, pregnancies or previous transplantations. The aim of our work was…
2017 American Transplant Congress
Polypharmacy and Frailty in Kidney Transplant Recipients.
H. Ying, M. McAdams-DeMarco, D. Segev.
Department of Surgery, Johns Hopkins Medicine Institute, Baltimore, MD
Frailty is common in kidney transplant (KT) recipients with a prevalence of 20%, and is associated with post-KT adverse events including mortality, DGF, early hospital…
2017 American Transplant Congress
Is There a [bdquo]Weekend Effect“ in Kidney Transplantation? – A Single Center Study.
K. Schütte-Nütgen, G. Thölking, H. Pavenstädt, B. Suwelack, S. Reuter.
Department of Internal Medicine D, University Hospital Münster, Münster, Germany
The "weekend effect" describes increased adverse events and outcomes for patients hospitalized on weekends due to limited resources at hospitals and - in the context…