ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    Conversion from Tacrolimus-Based to Everolimus-Based Immunosuppressive Therapy 3 Months After Living-Donor Kidney Transplantation: A Randomized-Controlled Clinical Trial.

    D. Hesselink,1 N. Shuker,1 J. Osinga,1 M. Clahsen -van Groningen,2 J. Damman,2 C. Baan,1 J. van de Wetering,1 A. Rowshani,1 J. Kal -van Gestel,1 W. Weimar,1 T. van Gelder,3 R. Bouamar.3

    1Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; 2Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands; 3Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands

    While conversion from ciclosporin to everolimus is well documented, conversion from tacrolimus has been poorly studied. In this randomized-controlled trial the safety and tolerability of…
  • 2017 American Transplant Congress

    Comparison of Long Term Renal Function Outcomes for Everolimus (EVR) vs. Sirolimus (SIR) vs. Mycophenolate Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant (Ktx).

    H. Tedesco,1 W. Irish,2 K. Dharmesh,3 D. Patel,3 D. Cibrik.4

    1Hospital do Rim UNIFESP, Sao Paulo, Brazil; 2CTI Consulting, Raleigh; 3Novartis Pharmaceuticals Corporation, East Hanover; 4University of Michigan, Ann Arbor

    MPA or mammalian target of rapamycin inhibitors (mTORi [EVR or SIR]) in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine) are used for maintenance…
  • 2017 American Transplant Congress

    Tacrolimus Dose Requirement Based on the CYP3A5 Genotype in Renal Transplant Patients.

    L. Qu, Z. Xie, H. Huang, H. Jiang, J. Chen, H. Jiang, H. Jiang, J. Chen, J. Chen, J. Chen.

    Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China

    Background The aim of the present study is to determine whether CYP3A5*A and CYP3A5*G genotype is a predictive index of tacrolimus dose requirement, and also…
  • 2017 American Transplant Congress

    Association Between Matrix-gla Protein Levels and Aortic Stiffness in Kidney Transplantation.

    M. Dinic,1 N. Maillard,1 P. Delanaye,2 J.-M. Krzesinski,2 A.-M. Saint-Remy,2 E. Cavalier,3 C. Mariat.1

    1Nephrology, Dialysis and Renal Transplantation, CHU Nord, Saint Etienne, France; 2Nephrology and Dialysis, University of Liège, CHU Sart Tilman, Liège, Belgium; 3Clinical Chemistry, University of Liège, CHU Sart Tilman, Liège, Belgium

    INTRODUCTIONAortic stiffness due to vascular calcifications is commonly observed among kidney transplant recipients and is considered as a predictive factor of poor events such as…
  • 2017 American Transplant Congress

    Impact of Six-Month Surveillance Biopsies and Monitoring in Pediatric Renal Transplant Recipients.

    J. Lyons,1,2,3 D. Ranch,1,2 R. Hall,1,2,3 P. Maxwell,1,2,3 K. Hitchman,1,2 Y. Hirase,3 B. Crowther.1,2,3

    1University Health System, San Antonio, TX; 2University of Texas Health Science Center San Antonio, San Antonio, TX; 3University of Texas College of Pharmacy, Austin, TX

    Purpose: Evaluate the utility of surveillance biopsies and monitoring 6 months post-transplant.Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011–10/2015…
  • 2017 American Transplant Congress

    An Argument for Expanding the Simultaneous Liver and Kidney Transplant Criteria: Validity of the New UNOS Allocation Policy.

    S. Nagai,1 M. Safwan,1 K. Collins,1 M. Rizzari,1 D. Moonka,2 K. Brown,2 A. Patel,3 A. Yoshida,1 M. Abouljuod.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI; 3Nephrology, Henry Ford Hospital, Detroit, MI

    Aim: According to the latest simultaneous liver-kidney transplant (SLK) allocation policy by UNOS, allocation of kidney is dependent on duration of low glomerular filtration rate…
  • 2017 American Transplant Congress

    Tangible Benefits in Caregiving Burden Among Spouses/Partners of Transplant Patients: Adding “Donor Benefit” to Live Donor Risk Assessment.

    S. Rasmussen, L. Duquette, M. Henderson, D. Segev.

    JHU, Baltimore

    Background The mental and physical health of spouses and co-habiting partners (dyads) are highly correlated. Dialysis entails significant caregiving burden and decreases the quality of…
  • 2017 American Transplant Congress

    25-Hydroxyvitamin D [25(OH)D], but Not 1,25-Dihydroxyvitamin D [1,25(OH)2D], Independently Predicts Kidney Graft Failure: The Wisconsin Allograft Recipient Database (WisARD).

    B. Astor,1 M. Melamed,2 D. Mandelbrot,1 A. Djamali.1

    1University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY

    Vitamin D deficiency is common in chronic kidney disease and is associated with cardiovascular events and mortality. Kidney transplant recipients are at elevated risk of…
  • 2017 American Transplant Congress

    Multi-Stakeholder Perspectives on the Importance of Outcomes for Trials in Kidney Transplantation: An International Best Worse Scaling Survey.

    M. Howell,1,2 N. Evangelidis,1,2 B. Sautenet,2 G. Wong,1,2,3 J. Craig,1,2 K. Howard,1 A. Tong.1,2

    1School of Public Health, University of Sydney, Sydney, Australia; 2Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia; 3Centre for Transplant Research, Westmead Hospital, Sydney, NSW, Australia

    To optimize the benefits of kidney transplantation, recipients and clinicians should have an agreed, shared management plan. This relies on prioritizing the same outcomes but…
  • 2017 American Transplant Congress

    Contribution of New Generation Sequencing to CMV Resistance Analysis in Renal Transplant Recipients (on Behalf of the CMV Resist Group).

    C. Danthu,1 M. Gomes-Mayeras,1 D. Andouard,2 E. Munteanu,1 R. Moulinas,1,4 G. Ligat,2 S. Hantz,1,2 J. Rerolle,3 F. Garnier,1 M. Essig,3 S. Alain.1,2,4

    1National Reference Center for CMV-Virology, CHU Limoges, Limoges, France; 2UMR Inserm 1092, Université Limoges, Limoges, France; 3Nephrology, CHU Limoges, Limoges, France; 4GenoLim/Biscem Genomic Platform, Université Limoges, Limoges, France

    Results from the French Cohorts 2006-2010 and OrphaVic (NCTNCT02067169) indicates that fifty percent of graft failures in renal recipients infected by HCMV after treatment with…
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