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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    Controlled Donation After Circulatory Death (cDCD) Donors May Become Similar to Brain Death Donors (DBD).

    C. Antoine,1 M. Videcoq,2 B. Riou,3 D. Dorez,4 G. Cheisson,5 L. Martin-Lefèvre,6 L. Durand,1 E. Savoye,1 G. Karam,2 B. Barrou.3

    1Agence de la Biomedecine, Saint Denis La Plaine, France; 2University Hospital, Nantes, France; 3University Hospital La Pitie, Paris, France; 4Hospital, Annecy, France; 5University Hospital, Kremlin Bicetre, France; 6Hospital, La Roche Sur Yon, France

    Since 2014 in France, we started a cDCD program characterized by the introduction of normothermia regional perfusion (nRP) and selection criteria as donor age ≤65…
  • 2017 American Transplant Congress

    Characteristics and Performance of Unilateral Deceased Donor Kidney Transplants.

    S. Husain,1 S. Lee,1 S. Mohan,1 S. Pastan,2 R. Patzer,2 M. Chiles.1

    1Columbia Univ, New York, NY; 2Emory Univ, Atlanta, GA

    Purpose:The fraction of kidneys procured for transplant that are discarded is rising in the United States. Identifying donors from whom only one kidney was discarded…
  • 2017 American Transplant Congress

    Association Between Transportation Strategies and Kidney Transplant Center Staff Perceived Racial Disparities.

    K. Lipford, L. McPherson, R. Hamoda, R. Patzer.

    Department of Surgery, Emory University, Atlanta, GA

    Background: Racial disparities exist in access to the transplant evaluation process. One contributing factor for this disparity is travel barriers. Transplant center policies to assist…
  • 2017 American Transplant Congress

    Renal Transplant Recipients with Indication for Antiplatelet Therapy: Increased Risk for the Allograft?

    T. Benko, M. Gottmann, S. Radunz, J. Treckmann, F. Saner, A. Paul, D. Hoyer.

    General Visceral and Transplantation Surgery, University Hospital, Essen, Germany

    Background Antiplatelet therapy is common in patients on the waiting list for kidney transplantation increasing the risk for perioperative blood loss. This study evaluates the…
  • 2017 American Transplant Congress

    TNF[part]-I After Kidney Transplantation.

    B. Muth, B. Astor, D. Mandelbrot.

    Department of Medicine, Division of Nephrology, University of Wisconsin, Madison, WI

    Infliximab, adalimumab and etanercept are monoclonal antibodies which inhibit tumor necrosis factor alpha (TNF[part]-I) and are used in the treatment of inflammatory diseases such as…
  • 2017 American Transplant Congress

    The Effiency and Safety of Chemotherapy for Urothelial Carcinoma in Post-Kidney Transplanted Patients.

    Y. Zhu, J. Lin.

    Urology, Capital Medical University Beijing Friendship Hospital, Beijing, China

    Objective: According to our published data, upper tract urothelial carcinoma (UTUC) is the predominant malignancy among Chinese renal transplanted patients. This is quite different from…
  • 2017 American Transplant Congress

    Analysis of ApoL1 and MYH9 Genetic Polymorphisms Among the Hispanic Kidney Allograft Recipients.

    Y. Chang,1,2 T. Shah,1,3 D. Min.1

    1Western University of Health Sciences, Pomona, CA; 2Mendez National Institute of Transplantation Foundation, Los Angeles, CA; 3St. Vincent Medical Center, Los Angeles, CA

    Introduction: Genetic polymorphisms of Apolipoprotein 1 (ApoL1) and non-muscle heavy chain 9 (MYH9) genes are known to be strongly associated with focal segmental glomerulosclerosis, HIV-associated…
  • 2017 American Transplant Congress

    Personalized Tacrolimus (TAC) Dosing Using Genetic Variants in Caucasian Kidney Transplant (Tx) Recipients.

    D. Margraf,1 R. Brundage,1 D. Schladt,2 W. Guan,3 B. Wu,3 R. Remmel,4 C. Dorr,2,7 D. Berglund,1 R. Mannon,5 A. Matas,6 W. Oetting,1 A. Israni,2,7 P. Jacobson,1 For the DeKAF Genomics Investigators.

    1Dept of Experimental and Clinical Pharmacology, Col of Pharmacy, Univ of Minnesota(UMN), Mpls, MN; 2Chronic Disease Research Group, MPLS Medical Research Foundation, Mpls, MN; 3Div of Biostatistics, School of Public Health, UMN, Mpls, MN; 4Dept of Med Chem, Col of Pharmacy, UMN, Mpls, MN; 5Dept of Nephrology, Univ of Alabama, Birmingham, AL; 6Div of Transplantation, Dept of Surgery, School of Medicine, UMN, Mpls, MN; 7Dept of Nephrology, Hennepin County Medical Center, School of Medicine, UMN, Mpls, MN

    TAC is an immune suppressant with a narrow therapeutic index and high pharmacokinetic (PK) variability leading to uncertainty in blood concentrations. We previously developed an…
  • 2017 American Transplant Congress

    Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Dosing.

    D. Hesselink,1 L. Andrews,2 B. de Winter,2 J. Tang,3 N. Shuker,2 R. Bouamar,2 R. van Schaik,4 B. Koch,2 T. Van Gelder.1

    1Internal Medicine, Erasmus MC, Rotterdam, Netherlands; 2Hospital Pharmacy, Erasmus MC, Rotterdam, Netherlands; 3Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China; 4Clinical Chemistry, Erasmus MC, Rotterdam, Netherlands

    Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting…
  • 2017 American Transplant Congress

    Pre-Transplant Panel Reactive T Cells (PRT) with IL-15 as a Risk-Stratifier of Acute Rejection in Kidney Transplant Patients on Belatacept Therapy.

    P. Cravedi,1 I. Gandolfini,1 C. Donadei,1 R. Fairchild,2 K. Newell,3 R. Mannon,4 P. Heeger,1 CTOT16 Consortium.

    1Dept of Medicine, Icahn School of Medicine at Mount Sinai, New York; 2Dept of Immunology, Cleveland Clinic, Cleveland; 3Dept of Surgery, Emory University, Atlanta; 4Renal Division, UAB, Birmingham

    While kidney transplant recipients treated with bela without calcineurin inhibitors (CNI) have better 5-10y eGFR versus those on CNI, Belatacept (bela) use is associated with…
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