ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    A Comparative Study of Patient and Graft Qualities Between Abo-Compatible and -Incompatible Recipients More Than Ten Years After Kidney Transplantation.

    H. Ishida, T. Shimizu, M. Okumi, K. Unagami, K. Omoto, K. Tanabe.

    Urology, Tokyo Women's Medical University, Tokyo, Japan

    Background. The long-term benefits of ABO-I kidney transplantation in terms of adverse events due to severe immunosuppression immediately before transplantation remain unclear.Patients and Methods. Between…
  • 2017 American Transplant Congress

    In Depth Characterization of Ex Vivo Expanded Polyclonal Regulatory T Cells Used in a Phase I Clinical Trial Following Kidney Transplantation.

    J. Heinrichs,1 J. Mathew,1,2 I. Konieczna,1 J. He,1 X. Haung,1 A. LeFever,1 J. Leventhal.1

    1Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL; 2Microbiology and Immunology, Northwestern University, Chicago, IL

    Initial clinical trials have investigated the safety of regulatory T cells (Tregs) as a therapy during aberrant immune activation, like graft-versus-host disease (GVHD) following stem…
  • 2017 American Transplant Congress

    Tacrolimus Dose Variability, CYP3A5 Genotype, and Acute Rejection in African American and European American Kidney Transplant Recipients.

    S. Seibert,1 D. Schladt,2 B. Wu,3 W. Guan,3 C. Dorr,2,7 D. Berglund,1 R. Remmel,4 A. Matas,5 R. Mannon,6 A. Israni,2,7 W. Oetting,1 P. Jacobson,1 For the DeKAF Genomics Investigators.

    1Dept of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota (UMN), Mpls, MN; 2Chronic Disease Research Group, Minneapolis Medical Research Foundation, Mpls, MN; 3Division of Biostatistics, School of Public Health, UMN, Mpls, MN; 4Dept of Medicinal Chemistry, College of Pharmacy, UMN, Mpls, MN; 5Division of Transplantation, Dept of Surgery, School of Medicine, UMN, Mpls, MN; 6Dept of Nephrology, University of Alabama, Birmingham, AL; 7Dept of Nephrology, Hennepin County Medical Center, School of Medicine, UMN, Mpls, MN

    Background: Poor immunosuppression with tacrolimus (TAC) after kidney transplantation contributes to the development of toxicity and loss of efficacy. We aimed to associate intra-patient TAC…
  • 2017 American Transplant Congress

    Optimization of Extended-Release Tacrolimus Dose with Mycophenolate Mofetile Based Immunosuppression in De Novo Kidney Transplant Recipients: 2 Years Outcome.

    Y. Watarai,1 S. Narumi,1 M. Okada,1 R. Kimura,1 K. Hatazoe,1 K. Futamura,1 T. Yamamoto,1 T. Hiramitsu,1 M. Tsujita,1 N. Goto,1 T. Kobayashi.2

    1Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan; 2Kidney Transplant Surgery, Aichi Medical University, Nagakute, Aichi, Japan

    Purpose: Once-daily tacrolimus extended-release formulation (TACER) has been accepted in kidney transplantation, however its optimal dosing are not well determined. We have validated the institutional…
  • 2017 American Transplant Congress

    Influence of Tacrolimus Metabolism Rate on Patients' Survival After Renal Transplantation.

    G. Thölking, J. Steinke, K. Schuette-Nuetgen, H. Pavenstädt, B. Suwelack, S. Reuter.

    Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, Münster, Germany

    Introduction: Tacrolimus (Tac) is an integral part of the immunosuppressive regimen after renal transplantation (RTx). A fast Tac metabolism rate defined as the Tac blood…
  • 2017 American Transplant Congress

    Cyclosporine Effects on Blood Pressure Are Exaggerated in Pubertal Girls After Renal Transplantation.

    A. Melk,1 R. Sugianto,1 B. Schmidt,2 K. Krupka,3 B. Höcker,3 B. Tönshoff,3 E. Wühl.3

    1Pediatric Nephrology, Hannover Medical School, Hanover, Germany; 2Nephrology, Hannover Medical School, Hanover, Germany; 3Pediatric Nephrology, University of Heidelberg, Heidelberg, Germany

    Hypertension is a common problem after renal transplantation. We investigated potential contributing factors for high blood pressure (BP) in 336 pediatric transplant recipients from the…
  • 2017 American Transplant Congress

    The Effects of Aspirin on Major Adverse Cardiac Events and Kidney Allograft Outcomes: A Meta-Analysis.

    W. Cheungpasitporn, C. Thongprayoon, D. Mitema, M. Mao, W. Kittanamongkolchai, M. Gonzalez-Suarez, S. Erickson.

    Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN

    BACKGROUND: The use of aspirin in chronic kidney disease patients has been shown to reduce myocardial infarction but may increase major bleeding. However, its effects…
  • 2017 American Transplant Congress

    Small Pediatric Donor Kidney Transplantation in Pediatric Recipients.

    H. Yaffe,1,2 P. Friedmann,2 L. Kayler.3

    1Surgery, Montefiore Medical Center, Bronx, NY; 2Surgery, Albert Einstein College of Medicine, Bronx, NY; 3Surgery, Erie County Medical Center, Buffalo, NY

    Kidneys from small pediatric donors (age <5 years, weight <21 kg) may be a means to increase the donor pool for pediatric recipients. Transplantation of…
  • 2017 American Transplant Congress

    A Retrospective Study on the Impact of Abdominal Surgical Histories on Hand-Assisted Laparoscopic Donor Nephrectomy for Living Donor Adult Kidney Transplant.

    T. Hiramitsu, K. Futamura, M. Okada, M. Tsujita, N. Goto, S. Narumi, Y. Watarai.

    Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan

    Background This study investigated the impact of hand-assisted laparoscopic donor nephrectomy (HALDN) for living donors with surgical histories.Methods During January 2009–May 2015, 555 living kidney…
  • 2017 American Transplant Congress

    Metabolomics Study for Identification of Potential Biomarkers of Long-Term Survival in Kidney Transplantation Recipients.

    C.-D. Kim, H.-Y. Jung, R.-H. Kim, S.-M. Park, J.-H. Park, K.-H. Lee, E.-S. Lee, K.-Y. Kim, J.-Y. Choi, J.-H. Cho, S.-H. Park, Y.-L. Kim.

    Division of Nephrology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea

    Background: The development of new strategies to improve long-term survival outcome after kidney transplantation is also becoming important. Although current diagnosis of allograft dysfunction relies…
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