Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Spiritual and Religious Faith of Actual and Potential Non-Directed (Altruistic) Living Kidney Donors.
A. Maghen,¹ G. Vargas,¹ S. Connor,¹ S. Nassiri,¹ E. Hicks,² L. Kwan,¹ S. Maliski,³ J. Veale.¹
¹Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA; ²Oregon Health and Science University, Portland, OR; ³University of Kansas Medical Center School of Nursing, Kansas City, KS
A. The recent rise in non-directed donors (NDDs) and their initiation of kidney chains offer innovative approaches to help address the overburdened kidney transplant waiting…
2017 American Transplant Congress
Immune Tolerance Monitoring in Renal Allograft Tolerance Induced by Transient Mixed Chimerism in Nonhuman Primates.
K. Hotta, T. Oura, A. Dehnadi, K. Huh, M. Matsunami, G. Benichou, J. Madsen, A. Cosimi, T. Kawai.
Center for Transplant Science, Massachusetts General Hospital, Boston, MA
Background: We have previously reported donor specific expansion of regulatory T cells (Tregs) in nonhuman primate (NHP) recipients which achieved renal allograft tolerance after induction…
2017 American Transplant Congress
Prevalence of CYP3A Genomic Variances and Impact on Tacrolimus Dosing Requirements in Kidney Transplant Recipients in Eastern North Carolina.
T. Asempa,¹ S. Hudson,² L. Rebellato,² A. Maldonado.¹
¹Vidant Medical Center, Greenville, NC; ²East Carolina University, Greenville, NC
BACKGROUND: African American (AA) patients are substantially more likely to express CYP3A5. Presence of CYP3A5 polymorphisms is an important pharmacotherapeutic consideration due to the extensive…
2017 American Transplant Congress
Steroid Free Maintenance Immunosupression in Kidney Transplantation: Indiana University Experience.
S. Hussain, T. Taber, A. Sharfuddin, M. Yaqub, W. Goggins, D. Mishler, O. Adebiyi.
Renal Transplant, Indiana University School of Medicine, Indianapolis, IN
Background: Steroid based maintenance Immunosuppression (IS) regimen is the standard protocol for many kidney transplant(tx) centers. However, concerns for chronic steroid impact on patients remains…
2017 American Transplant Congress
Detection of Shared and Distinct Gene Expression Signatures in Tissue and Urine During Acute Rejection of Kidney Grafts.
K. Keslar,¹ A. Zmijewska,² J. Chen,² K. Newell,³ P. Heeger,⁴ R. Mannon,² R. Fairchild.¹
¹Department of Immunology, Cleveland Clinic, Cleveland, OH; ²Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL; ³Department of Surgery, Emory University, Atlanta, GA; ⁴Department of Medicine, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY
A major goal of the Clinical Trials in Organ Transplantation (CTOT) studies is the identification of biomarkers that predict or diagnose acute graft rejection in…
2017 American Transplant Congress
Pulse Pressure After Renal Transplantation – Influence on Outcome: Results from the Collaborative Transplant Study.
B. Krüger,¹ B. Döhler,² B. Krämer,¹ C. Süsal.²
¹V. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Baden-Württemberg, Germany; ²Institut für Immunologie, Universitätsklinikum Heidelberg, Heidelberg, Baden-Württemberg, Germany
Systolic blood pressure (SBP) and diastolic blood pressure (DBP) are important predictors of graft and patient survival in renal transplant recipients. Pulse pressure (PP), the…
2017 American Transplant Congress
Pediatric Recipients of Deceased Adult Donor Kidneys Have Equivalent Outcomes Compared with Pediatric Donors.
D. Mikhail,¹ H. Sharma,^3,4 J. Chen,² M. Cooper,⁴ A. Sener,^1,3 P. Luke.^1,3
¹Urology, Western University, London, ON, Canada; ²Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; ³Multi-Organ Transplant Surgery, Western University, London, ON, Canada; ⁴Transplant Surgery, Georgetown University, Washington, DC
INTRODUCTION:Efforts are made to transplant paediatric deceased donor kidneys into pediatric recipients. To our knowledge, data does not support better graft outcomes with matched pediatric…
2017 American Transplant Congress
Optimizing Support for Living Kidney Donors: Insights from a Prospective Study.
D. Dobosz,¹ C. Thiessen,¹ S. Li,¹ K. Yu,¹ J. Gannon,¹ K. Kennedy,³ D. Gray,² A. Mussell,² P. Reese,² E. Gordon,³ S. Kulkarni.¹
¹Yale U, New Haven; ²U Pennsylvania, Philadelphia; ³Northwestern U, Chicago
PurposeTo assess how potential living kidney donors (LKDs) perceived support from the transplant team and areas for improvement.MethodsWe conducted a prospective, longitudinal study of individuals…
2017 American Transplant Congress
Predictors of Graft Loss in an Urban Predominantly Minority Cohort of Kidney Transplant Recipients.
N. Hayde, L. Kamal, M. Ajaimy, M. Lubetzky, P. Bedi, G. de Boccardo, E. Akalin.
Monterfiore/Einstein Center for Transplantation, Bronx, NY
BackgroundWe aimed to determine the demographic and clinical characteristics associated with graft loss in a cohort of kidney transplant recipients with a high African-American and…
2017 American Transplant Congress
Transplantation of Hepatitis C Kidneys to Hepatitis C Recipients Confers Significantly Shorter Waiting Times in the Era of the New Kidney Allocation System.
B. Concepcion, A. Langone, B. Edmundson, J. Johnson, A. Rajput, T. Johnson, D. Rybacki, D. Hale, R. Forbes.
Nashville VA Medical Center, Nashville, TN
Background: Prior to the new KAS, transplantation with HCV+ compared to HCV- kidneys provided shorter waiting times on the deceased donor list. In the current…