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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2017 American Transplant Congress

    TGF-β1 Induces Transplant Kidney Interstitial Fibrosis Through Endothelial-to-Mesenchymal Transition via TGF-β/Smad and Akt/mTOR/p70S6K Pathways.

    Z. Wang, Z. Han, J. Tao, R. Tan, M. Gu.

    Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

    Background: Chronic allograft dysfunction (CAD) induced by kidney interstitial fibrosis is the main cause of allograft failure in kidney transplantation. Studies suggested that endothelial-to-mesenchymal transition…
  • 2017 American Transplant Congress

    Prospective Monitoring of De Novo Donor-Specific Antibodies: Incidence, Clinical Outcomes and Dynamic Changes Over 5 Years After Kidney Transplantation.

    M. Ajaimy, A. Colovai, N. Hayde, J. Graham, M. Lubetzky, L. Kamal, G. De Bocardo, E. Akalin.

    Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, Bronx

    Background: We aimed to investigate the incidence and dynamic changes of de novo donor-specific-antibodies (dnDSA) after kidney transplantation and clinical outcomes.Methods: This is a prospective…
  • 2017 American Transplant Congress

    Normothermic Ex-Vivo Kidney Perfusion Improves Function of Extreme Marginal Renal Grafts Subjected to Prolonged Ischemia.

    P. Urbanellis,1 M. Hamar,1 I. Linares,1 D. Kollmann,1 C. Cassol,2 R. John,2 P. Yip,1 I. Mucsi,1 A. Ghanekar,1 D. Bagli,3 D. Grant,1 L. Robinson,4 M. Selzner.1

    1Multi-Organ Transplant Program, Department of Surgery, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 2Laboratory Medicine and Pathobiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 3Departments of Surgery (Urology) and Physiology, The Hospital for Sick Children, Toronto, ON, Canada; 4Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada

    Background: Normothermic ex-vivo kidney perfusion (NEVKP) is an emerging technique for renal graft preservation. We investigated whether NEVKP could promote improved marginal graft function compared…
  • 2017 American Transplant Congress

    Significance of Thrombotic Microangiopathy in Renal Allografts.

    B. Ozdemir,1 A. Ok Atilgan,1 M. Haberal.2

    1Pathology, Baskent University, Ankara, Turkey; 2Transplant Surgery, Baskent University, Ankara, Turkey

    Thrombotic microangiopathy (TMA) in the renal allograft is a form of renal capillary injury that may associate with many disorders including calcineurin inhibitor (CI) toxicity,…
  • 2017 American Transplant Congress

    A Comparison of Medical Costs Among ABO-Compatible, -Incompatible, and -Minor Mismatched Living Kidney Transplantation: A Single-Center Study.

    D. Fujimori, M. Okumi, K. Ungami, H. Ishida, K. Tanabe.

    Urology, Tokyo Women's Medical University, Tokyo, Japan

    [Background]ABO-incompatible living kidney transplantation (ABO-ILKT) is considered an effective alternative to deceased kidney transplantation. Although ABO-ILKT required extra strategies and suffered extra risks across ABO…
  • 2017 American Transplant Congress

    Effects of Anti-HLA Antibodies on Endothelial Expression and Serum Levels of Thrombomodulin in Kidney Recipients.

    S. Beland, O. Desy, P. Valin, S. De Serres.

    Medicine, Universite Laval, Quebec, QC, Canada

    Background: Thrombomodulin (TBM) is an anticoagulant and anti-inflammatory protein expressed on endothelial cells (ECs). Mutations of TBM are seen in thrombotic microangiopathies due to aHUS.…
  • 2017 American Transplant Congress

    Evaluation of Outcomes in Renal Transplantation Using Machine Perfusion for the Preservation of Kidneys from Expanded Criteria Donor.

    E. Savoye, M. Macher, Kidney Working Group, C. Legeai, C. Antoine.

    Agence de la Biomedecine, Saint Denis La Plaine, France

    Introduction:The shortage of kidney grafts led to retrieve organs from old donors with one or more co-morbidities, considered as “expanded criteria donors” (ECD). In France,…
  • 2017 American Transplant Congress

    Evaluating Online Information on Youtube for Kidney Transplant.

    P. Sheiner, S. Silver.

    Transplant Surgery, Hartford Hospital, Hartford, CT

    There are many frequently asked questions (FAQs) about kidney transplant that may not be answered by visits to the transplant center. Not all patients have…
  • 2017 American Transplant Congress

    Subpopulations of Peripheral Blood Monocytes in Kidney Allograft Recipients.

    I. Striz,1 V. Svachova,1 A. Sekerkova,1 J. Slatinska,2 K. Kopecka,1 M. Fialova,1 O. Viklicky.2

    1Department of Clinical and Transplant Immunology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic; 2Department of Nephrology, Transplant Centre, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic

    Human peripheral blood monocytes may be divided into different subsets based on the expression of membrane antigens. Our pilot data suggested that after the kidney…
  • 2017 American Transplant Congress

    Utility of a 10-Minute Functional Test as a Predictor of Kidney Transplant (KTP) Listing.

    M. Swee,1,2 J. Hornickel,2 R. Kalil.1,2

    1Transplant Nephrology, University of Iowa, Iowa City, IA; 2Transplant Nephrology, Iowa City Veterans Affairs Medical Center, Iowa City, IA

    Purpose: Frailty is a measure of physiologic reserve that has been associated with poor outcomes after kidney transplant, but its use as a predictor for…
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