2017 American Transplant Congress
Utility of Weighted Composite Endpoints in Kidney Transplantation.
Cleveland Clinic, Cleveland, OH
IntroductionAdvances in therapeutic development and innovation are stifled in transplantation based on difficulties demonstrating efficacy of novel interventions using standard endpoints. Current RCTs are constrained…2017 American Transplant Congress
Stability of Immune Phenotype, Alloreactive, and Antiviral Immunity After Switch to Belatacept-Based Regimen After Kidney Transplantation.
David Geffen School of Medicine at UCLA, Los Angeles, CA
Purpose: This investigator-initiated study examines the impact of belatacept on T cell immune phenotype and function.Methods: 14 patients who had completed the study protocol were…2017 American Transplant Congress
Urinary Proteomic Biomarkers Discovery for Prediction of Acute Rejection in Kidney Transplant Recipients.
Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea
Background: Early prediction and treatment of acute rejection are crucial in kidney transplant recipients (KTRs) to prevent allograft loss. Changes in the serum and urinary…2017 American Transplant Congress
Presence of Complement Activating Donor Specific Antibodies Is Associated with Poor Renal Allograft Survival: Two Centre Retrospective Study.
Introduction: Complement fixing donor specific antibodies (DSA) as detected by presence of C3d at the time of rejection is associated with poor graft outcome;no studies…2017 American Transplant Congress
The Impact of the Kidney Allocation System on Outcomes for Kidneys with KDPI > 85%.
Single center outcomes were examined to assess the impact of the implementation of the Kidney Allocation System (KAS) on outcomes for kidneys with KDPI >85%.Methods:…2017 American Transplant Congress
Validation of CYP4F11 as a Marker of Accommodation in Biopsies from Recipients of an ABO-Incompatible Renal Transplant.
Recipients of an ABO incompatible transplant have circulating anti-AB antibodies, A and/or B antigens expressed on endothelium and usually C4d deposition on the endothelium, yet…2017 American Transplant Congress
Postoperative Serum Lactate Dehydrogenase Is a "Troponin-Like" Marker of Renal Transplant Distress.
UCSD Center for Transplantation, University of California at San Diego, San Diego, CA
Lactate dehydrogenase (LDH) is plentiful in renal tubular cells and is released during tubular injury or death. It increases for several days to 1500-2000 U/L…2017 American Transplant Congress
Ciprofloxacin for Urinary Tract Infection Prophylaxis in Post-Renal Transplant Patients with Ureteral Stent Placement.
Hume-Lee Transplant Center, Virginia Commonwealth University Health, Richmond, VA
BackgroundUrinary tract infection (UTI) is the most common infection post renal transplant. Sulfamethoxazole-trimethoprim (SMX-TMP) is often the antibiotic drug of choice due to prophylaxis coverage…2017 American Transplant Congress
Role of Chemokines in Resolution of BK Virus-Associated Nephropathy and Chronicity of Pathology Changes in Kidney Transplant Recipients.
David Geffen School of Medicine at UCLA, Los Angeles, CA
BK virus-associated nephropathy (BKN) remains the most common infectious cause of allograft loss after kidney transplantation. We previously demonstrated increased frequency of polyfunctional T cells…2017 American Transplant Congress
Low-Dose Valganciclovir for Cytomegalovirus Prophylaxis in Intermediate Risk Renal Transplants: A Single Center Experience.
1Infectious Diseases, Yale University, New Haven, CT; 2Pharmacy, YNHH, New Haven, CT
IntroductionCurrent guidelines on cytomegalovirus (CMV) prophylaxis following organ transplant recommend using valganciclovir (VGCV) 900 mg daily for high (CMV D+/R-) and intermediate (CMV R+) risk…
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