Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Everolimus Does Not Increase Risk of Delayed Graft Function or Prolong Duration of Dialysis in Renal Transplantation.
F. Shihab,¹ Y. Qazi,² S. Mulgaonkar,³ K. McCague,⁴ D. Patel,⁴ V. Peddi,⁵ D. Shaffer.⁶
¹Univ of Utah, Salt Lake City; ²Univ of Southern California, Los Angeles; ³Barnabas Health, West Orange; ⁴Novartis, East Hanover; ⁵California Pacific Medical Center, San Francisco; ⁶Vanderbilt Univ Medical Center, Nashville
US92 (NCT01025817) is a phase III, 12 month, open-label, randomized study comparing everolimus (EVR) plus low-dose tacrolimus (LTac) vs. mycophenolate mofetil (MMF) with standard-dose tacrolimus…
2017 American Transplant Congress
Population Pharmacokinetic Profiling of Tacrolimus in Renal Transplant Recipients (RTRs) Taking Diltiazem.
P. Trevillian,^1,2,3 M. Heer,^1,2 S. Ainsworth,¹ A. Hibberd.^1,2,3
¹Newcastle Transplant Unit, John Hunter Hospital, Newcastle, NSW, Australia; ²University of Newcastle, Newcastle, NSW, Australia; ³Hunter Transplant Research Foundation, Hunter Medical Research Institute, Newcastle, NSW, Australia
Background: Over the past 6 years we have prospectively used pharmacokinetic (PK) profiling of Tacrolimus (TAC) in “stable” RTR's to individualise future dosing. This study…
2017 American Transplant Congress
Efficacy of Calcineurin Inhibitors Transferring to Rapamycin in Live Kidney Transplantation from Old Donors to Young Recipients.
G. Chen, C. Wang, Z. Wu, C. Wang, J. Qiu, L. Chen.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Background Calcineurin inhibitor(CNI) nephrotoxicity is one of the major reasons for chronic allograft injury in live kidney transplantation from old donors to young recipients. Therefore…
2017 American Transplant Congress
Post-Transplant Graft Function Is Associated with Major Cardiovascular Events in Kidney Transplant Recipients: A Multicenter Cohort Study.
J. Park,¹ Y. Kim,² S. Yang,³ S. Park,² S.-K. Park,⁴ D. Han,⁵ Y. Kim,² Y. Kim,⁵ J. Lee.⁶
¹Department of Internal Medicine, Dongguk University Ilsan Hospital, Gyeonggi-do, Korea; ²Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; ⁴Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁵Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁶Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea
Background: Reduced kidney function is an independent risk factor for cardiovascular disease in the general population. However, the association between post-transplantation graft function and subsequent…
2017 American Transplant Congress
The Clinical Significance of Red Cell Distribution Width (RDW) in Kidney Transplant Recipients.
S. Park,¹ J. Ha,¹ Y. Kim,¹ H. Lee,¹ Y. Kim,¹ C. Lim,¹ I. Jung,¹ D.-J. Han,² S.-K. Park,² Y. Kim,² J. Lee.¹
¹Seoul National University College of Medicine, Seoul, Korea; ²Asan Medican Center, Seoul, Korea
Background Increased red cell distribution width (RDW) has been known to be associated with worse prognosis in various populations. Although the levels of RDW are…
2017 American Transplant Congress
Impact of a Pharmacist-Led Vaccine Recommendation Program for Pediatric Kidney Transplant Candidates.
C. Carthon,¹ R. Hall,² P. Maxwell,² B. Crowther.²
¹Department of Pharmacy, Barnes-Jewish Hospital, St. Louis, MO; ²University Transplant Center, University Health System, San Antonio, TX
Pediatric transplant recipients commonly have a deficient immunization status at the time of transplantation. Utilizing transplant pharmacists to improve these immunization rates has not previously…
2017 American Transplant Congress
Challenges for the Travelling Donor: Variability Between Donor Work-Up and Donor Surgery in the Canadian Kidney Paired Donation Program.
B. Reikie, T. Kroczak, T. McGregor.
Surgery, University of Manitoba, Winnipeg, MB, Canada; Surgery, University of Toronto, Toronto, ON, Canada; Urology, Queen's University, Kingston, ON, Canada
Background: A primary obstacle to providing renal transplantation is limited access to donated kidneys. The living donor pool for renal allografts was greatly expanded through…
2017 American Transplant Congress
Seasonality of Mortality and Graft Failure Among Kidney Transplant Recipients in the US.
B. Astor,¹ M. Melamed,² D. Mandelbrot,¹ A. Djamali.¹
¹University of Wisconsin School of Medicine and Public Health, Madison, WI; ²Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY
The incidence of mortality in the general population is significantly higher in winter than in summer. It is unknown whether such a seasonal difference exists…
2017 American Transplant Congress
Use of Modified Geriatric Assessment in Evaluation of Older Adults for Kidney Transplant Suitability.
K. Campbell,¹ F. Enger, E. Patrick,² M. Saunders,³ M. Josephson,¹ Y. Becker.²
¹Medicine, University of Chicago, Chicago, IL; ²Kidney Transplant, University of Chicago, Chicago, IL; ³Hospital Medicine, University of Chicago, Chicago, IL
BackgroundThere is an increasing incidence and prevalence of older adults with ESRD. Per guideline recommendations, many of these patients are now being considered for kidney…
2017 American Transplant Congress
Tacrolimus Appears to Be a Protective Factor for De Novo DSA Formation in Non-Sensitized Kidney Transplant Patients.
M. Marron-Wojewodzki,¹ I. Szwarc,¹ C. Rene,² G. Mourad,¹ M. Le Quintrec.^1,3
¹Department of Nephrology, Dialysis and Transplantation, Hôpital Lapeyronie, Montpellier, France; ²Departement of Immunology, Hôpital Saint Eloi, Montpellier, France; ³Inserm U1183,, IRMB,Hôpital Saint Eloi, Montpellier, France
Background.Development of de novo donor specific antibodies (dnDSA) concerns about 10% of patients within the first year following kidney transplantation and reach about 20% within…