Articles tagged "Kidney transplantation"

2017 American Transplant Congress
Factors in Association with Sepsis Differ Between Simultaneous Pancreas/Kidney and Single Kidney Transplant Recipients.
T. Schachtner,^1,2,3 M. Zaks,¹ A. Kahl,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; ³Charite and Max-Delbrück Center, Berlin Institute of Health BIH, Berlin, Germany
As immunosuppressive therapy and allograft survival have improved in simultaneous pancreas/kidney transplant recipients (SPKTRs), the increased incidence of infection has become a major hurdle of…
2017 American Transplant Congress
Graft Loss from Anti-GBM Nephritis: A Rare Event in Alport Syndrome, Even with a Severe COL4A5/A4/A3 Mutation.
V. Gillion,¹ K. Dahan,² E. Goffin,¹ J.-P. Cosyns,³ M. Jadoul,¹ M. De Meyer,⁴ M. Mourad,⁴ Y. Pirson,¹ N. Kanaan.¹
¹Nephrology, Cliniques Universitaires Saint-Luc, Brussels, Belgium; ²Génétique Humaine, Institut de Pathologie et de Génetique, Gosselies, Belgium; ³Pathology, Cliniques Universitaires Saint-Luc, Brussels, Belgium; ⁴Surgery and Abdominal Transplantation, Cliniques Universitaires Saint-Luc, Brussels, Belgium
Background: Alport syndrome (AS) is caused by mutations in α3/α4/α5 (IV) collagen genes, whose severity determines the progression of AS. Post-transplant outcome is good, though…
2017 American Transplant Congress
Clinical and Pathologic Characteristics of Acute Rejection After Alemtuzumab Induction in Kidney Transplant Recipients.
P. Zhang,¹ H. Amer,² C. Schinstock,² M. Alexander,¹ F. Cosio,² M. Stegall,³ L. Cornell.¹
¹Anatomic Pathology, Mayo Clinic, Rochester; ²Nephrology, Mayo Clinic, Rochester; ³Transplant Surgery, Mayo Clinic, Rochester
Background: Alemtuzumab induction (AZI) can be used for early steroid withdrawal in kidney transplant (KTx) recipients. There is evidence that AZI-induced lymphocyte depletion leads to…
2017 American Transplant Congress
Accelerated De-Novo Donor-Specific Antibody-Mediated Rejection in a Non-Human Primate Model of Renal Transplantation.
J. Danobeitia, P. Chlebeck, J. Torrealba, T. Zens, L. Zitur, A. D'Alessandro, L. Fernandez.
Surgery - Division of Transplantation, University of Wisconsin-Madison, Madison, WI
The development of accelerated antibody-mediated rejection (ABMR) is associated with early allograft dysfunction and premature graft loss. In animals, pre-sensitization is usually required in order…
2017 American Transplant Congress
Kidney Donation After Brain Death Followed by Circulatory Death Confers Comparable Outcomes with Kidney Donation After Brain Death.
Q. Sun,¹ Q. Sun,¹ H. Zhou,² R. Cao,³ M. Lin,⁴ X. Hua,¹ L. Hong,¹ Z. Huang,¹ N. Na,¹ R. Cai,⁴ G. Wang,² F. Meng.³
¹Renal Transplantation, Lingnan Hospital, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; ²Urology, The First Affiliated Hospital, Jilin University, Changchun, China; ³Renal Transplantation, The Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Guangzhou, China; ⁴Renal Transplantation, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
The shortage of donor organs is an obstacle to meet the growing need of grafts. Although using DBD donors is the best available strategy, brain…
2017 American Transplant Congress
Ethnicity and Transplant Knowledge Among Canadian ESKD Patients.
D. Wong,¹ H. Ford,¹ C. Lok,¹ G. Nesrallah,² J. Peipert,³ C. Richardson,¹ A. Waterman,³ M. Novak,¹ I. Mucsi.¹
¹University Health Network, Toronto, ON, Canada; ²Humber River Hospital, Toronto, ON, Canada; ³David Geffen School of Medicine, UCLA, Los Angeles, CA
Background:Living donor kidney transplant (LDKT) offers improved life expectancy and better quality of life compared to deceased donor kidney transplant (DDKT) or dialysis. African and…
2017 American Transplant Congress
Simultaneous Heart and Kidney Transplant vs Heart Transplant: Single Center Review of Candidate Selection and List Management.
N. Fonseka,¹ H. Mangrolia,¹ S. Karhadkar,² S. Rao,² L. Punnoose.¹
¹Temple Heart and Vascular Institute, Lewis Katz School of Medicine at Temple University, Philadelphia, PA; ²Temple Kidney Transplant Program, Lewis Katz School of Medicine at Temple University, Philadelphia, PA
Background: Increasing numbers of patients with advanced heart and kidney failure undergo simultaneous heart kidney transplant (SHK). Selection criteria in patients with non-dialysis dependent kidney…
2017 American Transplant Congress
Improving Clinical Decisions for Kidney Transplant Recipients Through Online Medical Simulation.
S. Gitzinger, E. Jackson, D. Blevins.
Medscape, LLC, New York, NY
Methods: The CME intervention comprised two cases presented in a virtual patient simulation (VPS) platform, allowing learners to choose from numerous lab tests, diagnoses, and…
2017 American Transplant Congress
Efficacy and Safety of Direct Acting Antivirals in Kidney Transplant Recipients with Chronic Hepatitis C Virus Infection.
S. Hussain, T. Taber, M. Yaqub, O. Adebiyi, D. Mishler, A. Sharfuddin.
Indiana University Health, Indianapolis
Background: Chronic Hepatitis C Virus (HCV) infection has a negative impact on graft survival. Prior treatments were poorly tolerated and had minimal cure rates. The…
2017 American Transplant Congress
Induction of Tolerance to Renal Allografts in Non Human Primates by Concomitant Donor-Matched Vascularized Osteomyocutaneous Allotransplantation.
F. Zhong,¹ G. Zhao,² Y. Wang,³ J. Jiang,³ Y. Wang,¹ S. Ye,¹ S. Tao,¹ L. Cai,¹ X. Wang,¹ Q. Ye,¹ G. Chen,² X. Zheng.¹
¹Center for Transplantation Medicine, Wuhan University Zhongnan Hospital, Wuhan, Hubei, China; ²Transplantation, Tongji Hospital, Wuhan, Hubei, China; ³Surgery, Shanghai Dongfan Hospital, Shanghai, China
Introduction: We hypothesized that hematopoietic stem cell (HSC) niches in bone marrow of vascularized osteomyocutaneous allografts (VOMA) will facilitate mixed chimerism (MC) and tolerance to…