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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2022 American Transplant Congress

    Understanding The Modification Of Eplet Mismatch Risk By Immunosuppression Regimen

    A. Johnson1, X. Zhang1, L. Gragert2, C. Larsen1

    1Emory University School of Medicine, Atlanta, GA, 2Tulane University School of Medicine, New Orleans, LA

    *Purpose: Solid organ transplant donor-recipient eplet mismatch has been correlated with subsequent donor specific antibody (DSA) formation, antibody mediated rejection, and overall rejection rates. However,…
  • 2022 American Transplant Congress

    Race Misclassification in Kidney Transplantation Research

    A. Kernodle, V. Thompson, X. Chen, D. Segev, T. Purnell, M. McAdams-DeMarco

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Recently, the use of socially constructed “race” in kidney disease research has received national attention partly because of the research bias created when race…
  • 2022 American Transplant Congress

    Implementing Genetic Testing in the Evaluation of the Kidney Transplant Candidate

    F. Abu Al Rub1, Y. Caliskan2, H. Randall2, B. Bastani2, V. Fleetwood3, M. Nazzal2, C. Varma2, K. Lentine2

    1St. Louis University, St Louis, MO, 2St. Louis University, St. Louis, MO, 3Department of Transplantation, St. Louis University, St. Louis, MO

    *Purpose: To describe the incorporation of a genetic renal panel to improve the characterization of end stage kidney disease (ESKD) etiology in the kidney transplant…
  • 2022 American Transplant Congress

    Cutaneous Angiosarcoma in Solid Organ Transplant Recipients – Novel Case & Review of the Literature

    S. M. Elzein, R. R. Caplan

    Houston Methodist Hospital, Houston, TX

    *Purpose: Cutaneous angiosarcoma, a rare and extremely aggressive malignant neoplasm, has been described in fewer than twenty-five solid organ transplant recipients to date. Secondary, or…
  • 2022 American Transplant Congress

    Perturbations in Podocyte Transcriptome and Biological Pathways Induced by Injury Caused by FSGS Associated Circulating Factors

    P. Rashmi1, T. Sigdel1, D. Rychkov1, I. Damm1, F. Vincenti1, C. Craik1, J. Reiser2, M. Sarwal1

    1UCSF, San Francisco, CA, 2Rush University, Chicago, IL

    *Purpose: Focal segmental glomerulosclerosis (FSGS) remains a disease without specific therapy for primary disease and a high rate of recurrence after renal transplant. Circulating factors…
  • 2022 American Transplant Congress

    Tuberculosis (TB) Treatment without Rifampin in Kidney (K) and Kidney-Pancreas (KP) Transplantation (Tx)

    M. V. Radisic1, N. Pujato1, P. M. Bravo1, R. Del Grosso2, M. Hunter2, S. Beltramino3, L. Cornet1, R. Livia Franzini4, A. C. Dotta4, L. Leon4, J. Walther4, P. Uva5, G. Werber3, M. C. Rial4

    1Infectious Diseases, ITAC (Instituto de Trasplante y Alta Complejidad), Ciudad Autonoma de Buenos Aires, Argentina, 2Internal Medicine, ITAC (Instituto de Trasplante y Alta Complejidad), Ciudad Autonoma de Buenos Aires, Argentina, 3Critical Care, ITAC (Instituto de Trasplante y Alta Complejidad), Ciudad Autonoma de Buenos Aires, Argentina, 4Kidney Transplantation, ITAC (Instituto de Trasplante y Alta Complejidad), Ciudad Autonoma de Buenos Aires, Argentina, 5Kidney Pancreas Transplantation, ITAC (Instituto de Trasplante y Alta Complejidad), Ciudad Autonoma de Buenos Aires, Argentina

    *Purpose: TB is a diagnostic and therapeutic challenge in K/KP Tx. Pharmacokinetic interaction between rifampin (RFP) and mTOR /calcineurin inhibitors (CNI) led to use of…
  • 2022 American Transplant Congress

    Do Videos Work Better Than Digital Ads at Reaching Audiences? Examining Which Message Types Engage and Encourage Further Exploration of Living Donation

    L. A. Davis1, A. Livingston2, A. Waterman3

    1HMH, Houston, TX, 2Multiview, Irving, TX, 3Transplant Research and Education Center, Houston, TX

    *Purpose: Testing and examination of media campaigns focused on deceased donor transplant abound. Fewer studies examine the effectiveness of different media strategies at increasing not…
  • 2022 American Transplant Congress

    Donor Genetic Background Predisposes Differentiation and Accumulation of Regulatory T Cells in the Kidney Allografts

    X. Lai1, J. Wang1, S. Han1, C. Chunlei1, L. VanOsdol1, L. Gallon2, J. Leventhal2, M. Kandpal1, Z. Zhang1

    1Comprehensive Transplant Center, Microsurgery core, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL

    *Purpose: We have previously demonstrated that donor kidney-intrinsic innate immunity determines the severity of delayed graft function (DGF) in kidney transplantation and potentiates long kidney…
  • 2022 American Transplant Congress

    Clazakizumab® (anti-il-6) Desensitization in Highly-HLA Sensitized Patients Awaiting Kidney Transplant (nct03380962): Long-Term Follow Up

    A. Vo1, J. Tang1, N. Ammerman1, E. Huang1, X. Zhang2, M. Haas3, A. Peng1, R. Najjar1, S. Williamson1, C. Meyers1, S. Sethi1, K. Lim1, M. Gillespie1, N. Badash1, S. Jordan1

    1Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA, 2HLA Laboratory, Cedars Sinai Medical Ctr, Los Angeles, CA, 3Pathology, Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: IL-6 is a cytokine critical for B-cell activation and IgG production. Clazakizumab (CSL Behring LLC) is a humanized monoclonal aimed at the cytokine IL-6.…
  • 2022 American Transplant Congress

    External Validation of the Abbreviated Ibox Scoring System at One-Year Post Kidney Transplant as a Surrogate Endpoint for Death-Censored Graft Survival

    A. Klein1, L. Kosinski2, R. Muse2, A. Loupy3, O. Aubert3, G. Divard3, M. Stegall4, I. Helanterä5, W. E. Fitzsimmons1, I. O'Doherty1

    1Transplant Therapeutics Consortium, Critical Path Institute, Tucson, AZ, 2Critical Path Institute, Tucson, AZ, 3Paris Transplant Group, Paris, France, 4Mayo Clinic, Rochester, MN, 5Helsinki University Hospital, Helsinki, Finland

    *Purpose: The Transplant Therapeutics Consortium seeks to translate the iBox from Loupy et al., 2019 into a surrogate endpoint for five-year death-censored graft survival after…
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