Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antiviral Agents in Kidney Transplant Recipients with HCV: A Systematic Review and Meta-Analysis
X. Wang,¹ P. Tan,¹ T. Xiang,² Y. Qiu,¹ T. Song,¹ T. Lin.¹
¹Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; ²West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan Province, China.
Background: Outcome data on sofosbuvir (SOF)-based therapy in patients with kidney transplantation (KTx) with hepatitis C virus infection are limited with individual studies having a…
2018 American Transplant Congress
Use of Right or Left Kidneys in Living-Donor Kidney Transplantation. Comparative Study of 320 Cases
M. Perosa,¹ J. Branez,¹ H. Noujaim,¹ L. Mota,¹ B. Zeballos,¹ M. Castro,¹ G. Marchini,¹ L. Ianhez,¹ L. Alvim,¹ D. Machado,¹ C. Watanabe,¹ A. Saldanha,² H. Abensur,² W. Luconi,¹ T. Genzini-Miranda,³ R. Haddad,⁴ T. Genzini.¹
¹Leforte Hospital, Sao Paulo, Brazil; ²Beneficencia Portuguesa Hospital, Sao Paulo, Brazil; ³Medical School, PUC Sorocaba, Sorocaba, Sao Paulo, Brazil; ⁴Medical School, ABC, Sao Paulo, Brazil.
In more than 95% of worldwide living-donor kidney transplants(LDKT), the donor's left kidney (LK) is preferred because of technical difficulties and a shorter vein of…
2018 American Transplant Congress
Corner-Saving Renal Artery Anastomosis for Renal Transplantation
A. Akdur,¹ M. Kus,² G. Moray,¹ S. Yildirim,¹ F. Yarbug Karakayali,³ K. Caliskan,² M. Haberal.¹
¹Transplantation, Baskent University, Ankara, Turkey; ²Transplantation, Baskent University, Adana, Turkey; ³Transplantation, Baskent University, Istanbul, Turkey.
Introduction: Renal transplantation is the preferred treatment for most patients with end-stage renal disease. Postoperative vascular complications that significantly affect graft loss include renal artery…
2018 American Transplant Congress
Donor-Derived Cell-Free DNA Identifies Antibody-Mediated Rejection with Graft Injury in DSA-Positive Kidney Transplant Recipients
S. Jordan,¹ S. Bunnapradist,² J. Bromberg,³ A. Langone,⁴ D. Hiller,⁵ J. Yee,⁵ J. Sninsky,⁵ R. Woodward,⁵ A. Matas.⁶
¹Cedars-Sinai Medical Center, Los Angeles, CA; ²UCLA, Los Angeles, CA; ³University of Maryland School of Medicine, Baltimore, MD; ⁴Vanerbilt University Medical Center, Nashville, TN; ⁵CareDx, Brisbane, CA; ⁶University of Minnesota School of Medicine, Minneapolis, MN.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) discriminates active rejection in kidney transplant patients. Donor-specific antibodies (DSA) to HLA antigens are associated with risk of antibody-mediated rejection…
2018 American Transplant Congress
Mortality and Kidney Transplantation Outcomes among Chronic Dialysis Patients Who Are Seropositive for Hepatitis C Virus
D. Sawinski,¹ F. Kimberly,¹ L. Vincent,¹ S. Justine,¹ B. Colleen,¹ C. Jordana,¹ G. David,¹ L. Jayme,² W. Joe,³ R. Peter.¹
¹Univ of Pennsylvania, Philadelphia, PA; ²Univ of Alabama, Birmingham, AL; ³DaVita, Minneapolis, MN.
Hepatitis C virus (HCV) infection is common among patients receiving chronic dialysis. However, few studies have examined both survival on dialysis as well as transplantation…
2018 American Transplant Congress
Recurrence of Immunoglobulin A Nephropathy in Related Donor Kidney Transplant Recipients
M. Okumi,¹ D. Okada,¹ K. Unagami,² Y. Kakuta,¹ H. Shirakawa,³ T. Shimizu,⁴ K. Omoto,⁴ H. Ishida,¹ K. Tanabe.¹
¹Urology, Toyko Women's Medical University, Tokyo, Japan; ²Nephrology, Toyko Women's Medical University, Tokyo, Japan; ³Urology, Ohkubo Hospital, Tokyo, Japan; ⁴Urology, Toda Chuo General Hospital, Saitama, Japan.
BackgroundSecondary to an increase in the graft survival rates in patients undergoing successful kidney transplantation, an increase in the occurrence of recurrent glomerulonephritis has been…
2018 American Transplant Congress
Outcome Implications of Benzodiazepines and Opioid Co-Prescriptions before Kidney Transplantation
N. Lam,¹ M. Schnitzler,² D. Axelrod,³ V. Dharnidharka,⁴ D. Segev,⁵ A. Naik,⁶ H. Xiao,² R. Ouseph,² H. Randall,² G. Hess,⁷ B. Kasiske,⁸ D. Brennan,⁵ T. Alhamad,⁴ K. Lentine.²
¹Univ Alberta, Edmonton, Canada; ²Saint Louis Univ, St. Louis; ³Lahey Clinic, Burlington; ⁴Washington Univ, St. Louis; ⁵Johns Hopkins, Baltimore; ⁶Univ Michigan, Ann Arbor; ⁷Hennepin, Minneapolis; ⁸Symphony Health, Conshohocken.
Recent studies have identified co-prescription of benzodiazepines and opioids as a risk factor for adverse outcomes in the general population. We previously described associations of…
2018 American Transplant Congress
Worsening Racial/Ethnic Disparities in Pediatric Kidney Transplant Outcomes in the US
T. Purnell, X. Luo, L. Cooper, D. Crews, K. Covarrubias, A. Massie, D. Segev.
Johns Hopkins, Baltimore.
Purpose: We recently demonstrated narrowed racial/ethnic disparities in adult kidney transplant (KT) outcomes in the US. The goal of this study was to examine twenty-year…
2018 American Transplant Congress
Prolonged Cold Ischemia Storage of Renal Allografts Shifts DSA Specificity and Enchances Glomerular Injury
V. Gorbacheva, R. Fan, W. Baldwin, A. Valujskikh.
Immunology, Cleveland Clinic, Cleveland, OH.
Prolonged cold ischemia storage (CIS) of donor organs is a major risk factor for acute and chronic graft injury. The goal of this study was…
2018 American Transplant Congress
Relationship between Living Kidney Donor Follow-Up GFR and Recipient Graft Loss
C. Holscher,¹ T. Ishaque,¹ C. Haugen,¹ S. DiBrito,¹ K. Jackson,¹ A. Muzaale,¹ A. Massie,^1,2 M. Henderson,¹ J. Garonzik Wang,¹ D. Segev.^1,2,3
¹Johns Hopkins School of Medicine, Baltimore; ²Johns Hopkins School of Public Health, Baltimore; ³Scientific Registry of Transplant Recipients, Minneapolis.
In living kidney transplantation, it is reasonable to believe a donated kidney's function would be associated with the function of the donor's remaining kidney. Indeed,…