Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Clinical Trials and Electronic Health Records
J. Chen, S. Bhattachrya, M. Sirota, M. Sarwal, A. Butte.
Institute for Computational Health Sciences, University of California San Francisco, San Francisco; Deaprtment of Surgery, University of California San Francisco, San Francisco.
Background. Ethnic and gender disparities in solid organ transplantation (tx) have social and clinical implications.General disparities for donor access and complications within clinical-trial, national and…
2018 American Transplant Congress
Dehydropeptidase-Iinhibitor Reduces Tacrolimus-Induced Kidney Injury by Anti-Oxidative and Anti-Apoptotic Effect
K. Luo,¹ S. Lim,¹ J. Il,¹ Y. Shin,¹ E. Ko,^1,2 B. Chung,^1,2 H. Hwang,^1,2 C. Yang.^1,2
¹Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea; ²Transplant Research Center, The Catholic University of Korea, Seoul, Republic of Korea.
Background:Cilastatin is an inhibitor of dehydropeptidase-I which enhances the antibacterial activity of imipenem.Dehydropeptidase I is associated with not only the metabolism of the enzyme but…
2018 American Transplant Congress
Implementation of Intensive Standardized Follow-Up in Kidney Transplant Recipients
A. Crane, M. Eltemamy, T. Coy, P. Babbar, A. Sun, D. Jacobsen, M. Ponziano, E. Poggio, A. Wee, R. Fatica, V. Krishnamurthi.
Cleveland Clinic, Cleveland.
Introduction & Objective: Kidney transplant recipients have higher rates of prolonged hospitalization and readmission rates. We aimed to identify modifiable predictors of 30-day readmission and…
2018 American Transplant Congress
Donor Specific Antibodies and Clinical Outcomes in Kidney Transplant Recipients
S. Wan,^1,2 S. Chadban,^1,2 K. Wyburn.^1,2
¹Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; ²Sydney Medical School, University of Sydney, Sydney, Australia.
BACKGROUND: Donor specific antibodies (DSA) have been implicated in the development of acute rejection (AR) and graft dysfunction in kidney transplant recipients (KTx). However, limited…
2018 American Transplant Congress
Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85 in Older Recipients
A. Nickkholgh,¹ A. Agarwal,¹ A. Nishio Lucar,² K. Brayman,¹ A. Doyle,² J. Oberholzer.¹
¹Dept. of Surgery, University of Virginia Health System, Charlottesville, VA; ²Dept. of Internal Medicine, University of Virginia Health System, Charlottesville, VA.
Background: High kidney donor profile index (KDPI >85%) organs can grant earlier access to transplantation particularly for those who are frail, have limited waiting time…
2018 American Transplant Congress
Renal Allograft Transplantation among Middle Eastern Population with Alemtuzumab Induction
G. Mitro, O. Ekwenna, M. Rees, J. Ortiz.
University of Toledo College of Medicine, Toledo, OH.
Introduction: Renal allograft recipients of Middle Eastern (ME) heritage are often grouped together with Caucasians (CAU) for analysis. This abstract seeks to explore whether ME…
2018 American Transplant Congress
Use of Granulocyte Colony-Stimulating Factor for Leukopenia Post-Renal Transplant
S. Hamel,¹ V. Kuo,² D. Johnson,¹ R. Bloom,³ D. Sawinski,³ J. Trofe-Clark.^1,3
¹Pharmacy, Hosp of Univ. of Pennsylvania, Philadelphia; ²Pharmacy, Univ. of California San Francisco, San Francisco; ³Renal Division, Perelman School of Medicine, Univ. of Pennsylvania, Philadelphia.
Purpose: Leukopenia is a frequent complication in renal transplant recipients (RTRs). Granulocyte colony-stimulating factor (G-CSF) accelerates white blood cell (WBC) count recovery; but, published experience…
2018 American Transplant Congress
Results of UNOS Survey on Diagnosis, Treatment and Follow-Up Evaluation of Clinical and Sub-Clinical TCMR and ABMR in Kidney Transplant Recipients
P. Sood,¹ W. Cherikh,² A. Toll,² R. Mehta,¹ C. Puttarajappa,¹ S. Hariharan.¹
¹University of Pittsburgh Medical Center, Pittsburgh; ²UNOS, Richmond.
Management strategies for treatment of rejection post ktx vary among centers. Controlling minor degrees of inflammation can prevent chronic allograft scarring. To study the diverse…
2018 American Transplant Congress
Weight Changes before and after Kidney Donation
A. Bugeja,¹ S. Harris,² J. Ernst,¹ K. D. Burns,¹ G. Knoll,¹ E. G. Clark.¹
¹Medicine, The Ottawa Hospital, Ottawa, ON, Canada; ²Faculty of Science, University of Ottawa, Ottawa, ON, Canada.
IntroductionLiving kidney donors remain at low risk of end stage kidney disease but obese and overweight donors' risk is increased. We aimed to describe the…
2018 American Transplant Congress
Ischemia Reperfusion Injury & Risk for Antibody Mediated Rejection (ABMR) in HLA Sensitized Patients Treated with C1 Esterase Inhibitor (C1INH)
A. Vo,¹ O. Aubert,² J. Choi,¹ N. Ammerman,¹ H. Edmund,¹ A. Peng,¹ R. Najjar,¹ S. Supreet,¹ S. Jordan.¹
¹Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; ²Paris Translational Research for Organ Transplantation, Necker Hospital, Paris, France.
Introduction: Ischemia reperfusion injury (IRI) contributes to delayed graft function (DGF). IRI/DGF in HLA-sensitized (HS) patients likely activates innate and memory injury pathways that may…