Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Kidney Transplant Alone Recipients with Advanced Liver Disease Have Similar Outcomes to Those without Advanced Liver Disease
R. R. Nathani, S. M. Rutledge, C. Villarroel, R. Shapiro, G. Y. Im
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: The prevalence of concomitant liver disease (CLD) in patients with ESRD is reported to be 7-40%. Safety of kidney transplant alone (KTA) in those…
2022 American Transplant Congress
Experience with Covid-19 Infection and Vaccination in Combined Kidney/HSCT Recipients
M. Gibson¹, D. Belshe¹, G. Gregory¹, S. Tanna¹, M. Ison¹, S. Ildstad², J. R. Leventhal¹
¹Northwestern University, Chicago, IL, ²University of Louisville, Louisville, KY
*Purpose: Kidney transplant(KTx) recipients are at increased risk of COVID-19 related complications. KTx pts who have undergone therapy to induce tolerance are a unique cohort…
2022 American Transplant Congress
Recipient’s Age Does Not Impact Survival After Simultaneous Heart and Kidney Transplant
F. Aziz¹, F. Raza¹, S. Parajuli¹, T. Hess¹, A. Feidler¹, D. Mandelbrot², A. Djamali¹, R. Dhingra³
¹University of Wisconsin, Madison, WI, ²UW Health, Madison, WI, ³University of Wisconsin School of Medicine and Public Health, Madison, WI
*Purpose: Simultaneous heart and kidney transplantation (SHKT) is the treatment of choice for patients who suffer both from end-stage heart and kidney disease. However, the…
2022 American Transplant Congress
Unravelling the Stage-Shift of Acute Rejection by Urine QSant
W. Yazar¹, N. Titzler¹, R. Sarwal¹, M. Sarwal², S. Ghosh¹
¹Nephrosant, Brisbane, CA, ²NephroSant, Brisbane, CA
*Purpose: Suboptimal performance in current methods for allograft monitoring underscores the unmet need for enhanced immunosurveillance accuracy, to uncover the alloimmunity flux. QSant[Yang et al,…
2022 American Transplant Congress
Detection of Microbiota from Catheter Tip in Hemodialysis Patients During the Perioperative Period of Kidney Transplantation Based on Metagenomics: A Prospective Study
Z. Yan, Y. Wang, W. Zeng, R. Xia, W. Deng, J. Xu, Y. Miao
Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China
*Purpose: Catheter-related infection (CRI) is the most serious complication in dialysis patients. However, current studies are limited to routine culture or immunological examination of CRI.…
2022 American Transplant Congress
Improved Mortality in COVID-19 Kidney Transplant Recipients Treated with Bamlanivimab
A. Hamiduzzaman, U. Reddy
Nephrology, UC Irvine, Orange, CA
*Purpose: Transplant recipients are particularly vulnerable to catastrophic sequelae of COVID-19. In an early multi-center study of 482 solid organ transplant (SOT) recipients with COVID-19,…
2022 American Transplant Congress
The Role of LAG3 in Antibody Responses to Kidney Transplantation
M. Nicosia¹, R. Fan¹, J. Lee², V. Gorbacheva¹, A. M. Beavers¹, N. Dvorina¹, W. Baldwin III¹, R. L. Fairchild¹, B. Min³, A. Valujskikh¹
¹Inflammation and Immunity, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, ²Cardiovascular and Metabolic Science, Cleveland Clinic, Lerner Research Institute, Cleveland, OH, ³Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL
*Purpose: The functions of coinhibitory receptor lymphocyte activation gene-3 (LAG3) in T cells are well studied, however its role in humoral immune responses remains poorly…
2022 American Transplant Congress
Associations of Immunosuppression Regimen with Fracture Risk After Kidney Transplant in High-Risk Populations: Identifying Targets for Risk-Reduction
K. Lentine¹, S. Kupacchi², W. Cheungpasitporn³, R. Li⁴, Y. Caliskan⁴, M. Schnitzler⁴, M. McAdams-DeMarco⁵, J. Ahn⁵, S. Bae⁶, G. Hess⁷, D. Segev⁵, D. Axelrod²
¹Saint Louis University Center for Abdominal Transplantation, St. Louis, MO, ²U Iowa, Iowa City, IA, ³Mayo Clinic, Rochester, MN, ⁴Saint Louis University, Saint Louis, MO, ⁵Johns Hopkins, Baltimore, MD, ⁶Johns Hopkins, Baltimore, MO, ⁷Drexel, Philadelphia, MO
*Purpose: Disorders of bone and mineral metabolism frequently develop with advanced kidney disease, may be exacerbated by immunosuppression (ISx) after kidney transplant (KTx), and may…
2022 American Transplant Congress
Combined Genome Wide and Single Nuclei Transcriptomics in Posttransplant Acute Kidney Injury Identifies Early Proinflammatory/Profibrogenic Cell Origin
J. McDaniels¹, T. Rousselle¹, E. Bardhi¹, A. Shetty¹, E. Akalin², D. Maluf¹, V. Mas¹
¹University of Maryland, Baltimore, MD, ²Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY
*Purpose: Kidney transplants offer a unique opportunity to evaluate molecular pathways involved in development and response to acute kidney injury (AKI). This prospective study of…
2022 American Transplant Congress
Impact of Early versus Late Initiation of Sirolimus Regimens on Mortality After Kidney Transplantation: Age-Stratified Analyses of Adult Recipients
A. Santos¹, H. Ibrahim¹, M. A. Leghrouz¹, X. Wen²
¹University of Florida, Gainesville, FL, ²University of Rhode Island, Kingston, FL
*Purpose: Observational and meta-analytic studies have associated sirolimus with an increased risk of mortality in kidney transplant (KT) recipients (KTRs). We aimed to examine the…