2018 American Transplant Congress
A Phase-I Clinical Trial of Donor-Derived MIC Cell Infusion for the Induction of Donor-Specific Hyporesponsiveness after Living Donor Kidney Transplantation (TOL-1 Study)
MIC cells are donor-derived monocytes that gain immunosuppressive properties after incubation with the proliferation inhibitor mitomycin C.PBMCs were harvested from living donors by leukapheresis and…2018 American Transplant Congress
Long-Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients
1Surgery, Northwestern U, Chicago; 2U of Louisville, Louisville; 3Duke U, Durham.
37 pts have been transplanted in a phase 2 protocol to induce tolerance in recipients of living donor renal allografts (KTx). The protocol is based…2018 American Transplant Congress
The Inhibitory Effect of Plasma on Activation of Lymphocytes from Kidney Transplants is Significantly More Severe in Tacrolimus Based Regimen: What Implications for Plasma Exchange Role in Anti-Rejection Therapy?
Background:Reduction of lymphocyte proliferation by human plasma has been previously reported. Reduced activation of lymphocytes of patients on immunosuppressive drugs is well documented. However, trial…2018 American Transplant Congress
Diagnosis of Antibody-Mediated Rejection after Kidney Transplantation by Blood Expression of Genes Involved in IFN Signaling
Purpose: Antibody-mediated rejection (ABMR) has been recognized as a major cause of graft loss. Early diagnosis and effective treatment are crucial for salvaging grafts undergoing…2018 American Transplant Congress
An Increase in Spot Urine Protein Excretion during the First Year after Kidney Transplantation Associates with Subclinical De-Novo Donor-Specific Antibodies and Microvascular Inflammation at 1-Year Surveillance Biopsies
Introduction. We investigated whether an increase in spot urine protein excretion during the first year after kidney transplantation associates with subclinical de-novo donor-specific antibodies (DSA)…2018 American Transplant Congress
Kidney Transplantation in ESKD Patients with a History of Sickle Cell Disease/Trait
Introduction:Kidney transplantation in Sickle Cell Disease patients is fraught with complications, including increased risk of infection and thrombosis. We present long term outcomes of patients…2018 American Transplant Congress
Transplant Candidates and Potential Living Kidney Donors Are Supportive of Reciprocity for Transplant Candidates Who Participate in Kidney Paired Donation with a Compatible Donor
1UBC, Vancouver, Canada; 2Centre de Recherche du CHUM, Montreal, Canada.
The inclusion of compatible pairs in kidney paired donation (KPD) is a strategy to increase transplantation for incompatible pairs in KPD. We proposed a reciprocity…2018 American Transplant Congress
Effect of Influenza Vaccine in Patients with Kidney Transplant
Objective: In this study, we aimed to evaluate the effect of influenza vaccine in kidney transplant recipients.Methods: We retrospectively studied 98 participants who underwent kidney…2018 American Transplant Congress
5-Year Serum Alkaline Phosphatase Levels after Kidney Transplantation is Associated with Long-Term Graft Survival and Mortality in Kidney Recipient
Background: Previous studies have attempted to identify risk factors of renal graft injury that can be used to improve long-term graft survival. Recently, higher serum…2018 American Transplant Congress
High Prevalence of New Onset Diabetes Mellitus in a Predominantly Minority Urban Cohort of Kidney Transplant Recipients and Clinical Outcomes
Montefiore Medical Center, Albert Einstein College of Medicine, Bronx.
Background: We aimed to determine the prevalence of new onset diabetes after transplant (NODAT) and its association with clinical outcomes in a cohort of predominantly…
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