Articles tagged "Kidney transplantation"

2018 American Transplant Congress
400 Kidney Paired Donor Transplants at a Single Center; The Methodist San Antonio Experience
A. Bingaman,¹ M. Kapturczak,¹ I. Ashlagi,² C. Murphey.³
¹Methodist Specialty and Transplant Hospital, San Antonio, TX; ²Stanford University, Palo Alto, CA; ³Southwest Immunodiagnostics, San Antonio, TX.
Background: Kidney paired donation (KPD) has become the standard of care for incompatible living donor pairs. Several mature national KPD programs exist yet KPD transplants…
2018 American Transplant Congress
Unbiased Sequencing of Urine Cell-Free DNA (cfDNA) to Evaluation Urine Virome and Associated Renal Allograft Damage
D. Dadhania,¹ P. Burnham,² J. Lee,¹ C. Snopkowski,¹ C. Li,¹ S. Albakry,¹ H. Yang,¹ T. Muthukumar,¹ I. De Vlaminck,² M. Suthanthiran.¹
¹Transplantation Medicine-Nephrology, Weill Cornell Medicine, NY, NY; ²Biomedical Engineering, Cornell University, Ithaca, NY.
Intro: Virus reactivation leading to graft damage is a frequent post-kidney transplant (KTx) complication. Immunosuppressed individuals are at risk for multiple virus infections simultaneously. Current…
2018 American Transplant Congress
The Impact of Aorto-Iliac Calcifications on Patient and Graft Survival in Renal Transplant Recipients Using the TASC II Classification
A. Rijkse,¹ M. van der Zijden,² J. Roodnat,² S. Ten Raa,³ D. Bijdevaate,⁴ K. Muller,¹ J. IJzermans,¹ H. Kimenai,¹ R. Minnee.¹
¹Department of Transplantation Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; ²Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; ³Department of Vascular Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; ⁴Department of Radiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Introduction: Kidney transplantation (KTx) is the therapy of choice in patients with end-stage renal disease. Aorto-iliac calcifications (AIC) are a relative contra-indication for KTx, even…
2018 American Transplant Congress
The Results of the PRISM (Prediction of Rejection In Sensitized Patient Blood SaMples) Trial with a Novel Bioassay
F. Vincenti, A. Schroeder, S.-C. Hseish, J. Liberto, P. Towfighi, C. Koh, T. Sigdel, M. Sarwal.
Surgery and Medicine, University of California San Francisco, San Francisco.
Background. kSORT, a 17 gene blood biomarker, has been retrospectively validated for detection of BPAR and immune quiescence in kidney tx. This is the first…
2018 American Transplant Congress
Primary Cytomegalovirus Infection in Seronegative Kidney Transplant Patients is Associated with Prolonged Cold Ischemic Time of Seropositive Donor Organs
C. Falk,^1,7 F. Schlott,^2,7 K. Katsrintaki,^1,7 D. Steubl,³ W. Puppe,⁴ C. Blume,⁵ H. Haller,⁶ L. Renders,³ U. Heemann,³ D. Busch,² M. Neuenhahn.^2,7
¹Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; ²Institute for Medical Microbiology, Immunology and Hygiene, Technical University Munich, Munich, Germany; ³Department of Nephrology, Technical University Munich, Munich, Germany; ⁴Institute of Virology, Hannover Medical School, Hannover, Germany; ⁵Institute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany; ⁶Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany; ⁷DZIF TTU-IICH, DZIF, Hannover / Munich, Germany.
Introduction: Human Cytomegalovirus (CMV) infection is still a major risk factor for immunocompromised patients, e.g. kidney recipients. Based on the CMV serostatus of donor (D)…
2018 American Transplant Congress
An Integrative Approach for the Assessment of Peritubular Capillaritis Extent and Score in Microvascular Inflammation – Association with Transplant Glomerulopathy and Graft Loss
N. Kozakowski,¹ H. Herkner,² F. Eskandary,³ M. Eder,³ W. Winnicki,³ G. Bond,³ Ž. Kikić.³
¹Department of Pathology, Medical University of Vienna, Vienna, Austria; ²Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria; ³Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria.
Background:Banff Classification accepts two histomorphological features as surrogates of HLA Antibody-Antigen interaction on renal endothelium: C4d staining and microvascular inflammation scores (MVI sum score:ptc+g≥2) which…
2018 American Transplant Congress
The Treatment of Antibody-Mediated Rejection in Kidney Transplantation: An Updated Systematic Review and Meta-Analysis
S. Wan,^1,2 T. Ying,^1,2 K. Wyburn,^1,2 D. Roberts,^3,4 M. Wyld,^1,2 S. Chadban.^1,2
¹Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; ²Sydney Medical School, University of Sydney, Sydney, Australia; ³Department of Renal Medicine, Canberra Hospital and Health Services, Canberra, Australia; ⁴Medical School, Australian National University, Canberra, Australia.
Introduction: Current treatment strategies for antibody-mediated rejection (AMR) in kidney transplantation are based on low quality data from a small number of controlled trials. Novel…
2018 American Transplant Congress
Decreased Clinical Significance of Isoagglutinin Titer with the Current Desensitization Protocol in ABO-Incompatible Kidney Transplantation
C. Baek, H. Kim, W. Yang, D. Han, S-.K. Park.
Department of Internal Medicine, Division of Nephrology, Asan Medical Center, Seoul, Republic of Korea; Department of Surgery, Asan Medical Center, Seoul, Republic of Korea.
ABO-incompatible (ABOi) kidney transplantation (KT) has become a routine procedure with graft survival rates comparable to those of ABO-compatible KT. However, the clinical significance of…
2018 American Transplant Congress
Compatible Donor and Recipient Pairs' Perspectives on Participation in Kidney Paired Donation Programs: The Emotional Implications of Indirect Donation and Transplantation
M. Fortin,¹ J. Gill,² F. Ballesteros,¹ J. Gill.²
¹CHUM, Montreal, Canada; ²UBC, Vancouver, Canada.
The inclusion of compatible pairs in kidney paired donation (KPD) may be a strategy to increase the chance of transplantation for incompatible pairs in KPD…
2018 American Transplant Congress
Cryptococcal Infections in Kidney Transplant Recipients. A Single Center Experience
M. Radisic,¹ N. Pujato,¹ A. Dotta,² R. Livia Franzini,² M. Bravo,¹ L. Rodriguez Rilo,¹ C. Giampieri,² L. Leon,¹ M. Rial,¹ D. Casadei.¹
¹Infectious Diseases, Instituto de Nefrologia de Buenos Aires, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina; ²Kidney Transplantation, Instituto de Nefrologia de Buenos Aires, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina.
Cryptococcal infections are infrequent but a cause of morbidity & mortality in transplant (T) recipients. Best treatment and the need for secondary prophylaxis are still…