ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2018 American Transplant Congress

    Non-Invasive Proteomics to Detect Biomarkers for Kidney Allograft Dysfunction

    M. Watson,1 M. Srivastava,3 D. Little,1 O. Eidelman,3 R. Nee,1 A. Bera,3 J. Karaian,3 D. Oliver,1 H. Pollard,3 R. Jindal.2

    1Nephrology, USU-Walter Reed, Bethesda, MD; 2Surgery, USU-Walter Reed, Bethesda, MD; 3Anamtomy, Physiology and Genetics, USU-School of Medicine, Bethesda, MD.

    Background: Non-invasive biomarkers are needed for monitoring patients to predict early acute rejection (AR). We hypothesized that protein biomarkers released from rejecting allograft tissues can…
  • 2018 American Transplant Congress

    Urinary TIMP-2 Predicts the Presence and Duration of Delayed Graft Function in DCD Kidney Transplant Recipients

    J. Bank,1 R. Ruhaak,2 D. Soonawala,1 F. Romijn,2 C. van Kooten,1 C. Cobbaert,2 H. de Fijter.1

    1Nephrology, Leiden University Medical Center, Leiden, Netherlands; 2Clinical Chemistry and Laboratory Medicine, Leiden University Medical Center, Leiden, Netherlands.

    Introduction: Tissue inhibitor of metalloproteinases-2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) are promising biomarkers in acute kidney injury. Here, we investigated the performance…
  • 2018 American Transplant Congress

    C1q-Binding Donor-Specific Anti-HLA Antibodies for Clinical Decision Making in Kidney Recipients with Antibody-Mediated Rejection Receiving Standard of Care Treatment

    C. Lefaucheur,1 D. Viglietti,1 Y. Bouatou,1 O. Aubert,1 A. Zeevi,2 A. Loupy.1

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2University of Pittsburgh Medical Center, Pittsburgh.

    One of the major issues in the clinical management of kidney recipients with ABMR is the lack of early and reliable markers that surrogate long-term…
  • 2018 American Transplant Congress

    Antibody Mediated Kidney Transplant Rejection Treated with Bortezomib – Case Series from a Single Center

    G. Piecha,1 R. Król,2 H. Karkoszka,1 A. Wiecek.1

    1Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland; 2Department of General, Vascular and Transplantation Surgery, Medical University of Silesia, Katowice, Poland.

    Acute antibody mediated kidney transplant rejection (ABMR) is not a frequent complication but may have a catastrophic consequences for graft survival. Between January 2015 and…
  • 2018 American Transplant Congress

    Immuoadsorption-Based Desensitization in Highly Sensitized Patients Awaiting Deceased Donor Kidney Transplantation.

    C. Bureau, P. Galichon, Y. Luque, N. Ouali, E. Rondeau, C. Rafat.

    Urgences Néphrologiques et Transplantation Rénale, Tenon Hospital, APHP, Paris, France.

    An estimated 30% of patients on the waiting list are deemed highly sensitized due to preexisting anti-HLA antibodies often irrevocably precluding kidney transplantation (KT). Immunoadsorption…
  • 2018 American Transplant Congress

    Cause of ESRD is Not Associated with Risk of Post-Transplant CMV Infection

    S. Panzer, S. Peery, B. Astor, A. Djamali, T. Singh.

    University of Wisconsin Madison, Madison, WI.

    Purpose: Cytomegalovirus (CMV) infection is commonly encountered following kidney transplantation and is associated with patient morbidity and mortality. While preventative pharmacotherapy is used to prevent…
  • 2018 American Transplant Congress

    Association of Tacrolimus Adherence and Discontinuation with Sepsis Risk among Kidney Transplant Recipients

    J. Donnelly,1 P. MacLennan,1 R. Mannon,1 R. Saran,2 J. Baddley,1 H. Wang,3 G. McGwin, Jr.,1 P. Muntner.1

    1University of Alabama at Birmingham, Birmingham, AL; 2University of Michigan, Ann Arbor, MI; 3University of Texas Health Science Center, Houston, TX.

    OBJECTIVE: The association between post-transplant tacrolimus exposure and sepsis risk is currently unknown. We examined the associations of tacrolimus adherence and discontinuation with sepsis risk…
  • 2018 American Transplant Congress

    The Impact of Anticoagulation Therapy Modifications during the Index Hospitalization on Clinical Outcomes in Kidney Transplant Recipients

    J. Hardcopf, H. Meadows, N. Pilch, C. Perez, N. Patel, J. Fleming, H. Corbo, T. Harrison, B. O'Brien, D. DuBay, P. Baliga, D. Taber.

    Medical University of South Carolina, Charleston, SC.

    Background: The aim of this study was to determine whether changing anticoagulation medications during the index admission for kidney transplant (KT) is significantly associated with…
  • 2018 American Transplant Congress

    Hospitalization, Dialysis Center Type, and Disparities in ESRD Survival and Waitlist Access

    R. Lynch, R. Zhang, A. Adams, R. Patzer.

    Surgery, Emory University, Atlanta, GA.

    Background: Excess hospitalization has been shown to reduce kidney transplant waitlist survival and likelihood of transplant. We studied hospitalization as a predictor of waitlist access…
  • 2018 American Transplant Congress

    The Providers Can't Let Go! An Analysis of an RN Driven Tacrolimus Dose Adjustment Protocol

    Z. Elmaasarani, C. Mardis, L. Gylten, J. Fleming, H. Meadows, N. Patel, C. Perez, D. Taber, V. Rao, V. Rohan, P. Baliga, D. Dubay, N. Pilch.

    MUSC, Charleston.

    Introduction: Tacrolimus (FK) dose adjustment is frequently performed by non-MD staff. Standard protocols to evaluate the ability of non-providers to maintain pts within a goal…
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