Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Impacts of HBsAg Seropositive Status on Patient and Graft Survival after Kidney Transplantation in the Era of New Antiviral Therapy: A Meta-Analysis
N. Leeaphorn,¹ C. Thongprayoon,² K. Sharma,² A. Sakhuja,³ W. Cheungpasitporn.⁴
¹Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; ²Department of Medicine, Bassett Medical Center, Cooperstown, NY; ³Department of Medicine, Mayo Clinic, Rochester, MN; ⁴Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS.
BACKGROUND: An association between HBsAg seropositive status and increased mortality after kidney transplantation has been demonstrated in previous studies over the past decade. Although chronic…
2018 American Transplant Congress
Thirty-Six Consecutive Kidney Transplants in Recipients with Atypical Hemolytic Uremic Syndrome: A Single-Centre Experience
E. Favi,¹ G. Ardissino,² D. Cresseri,³ J. Brocca,¹ S. Testa,⁴ F. Tel,⁴ A. Giussani,¹ C. Colico,¹ C. Beretta,¹ M. Ferraresso.¹
¹Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; ²Centre for HUS Prevention, Control and Management, Fondazione IRCCS Ca' Granda, Milan, Italy; ³Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy; ⁴Pediatric Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.
Background. Due to high recurrence rate, poor kidney transplant (KTx) survival has been reported for recipients with atypical hemolytic uremic syndrome (aHUS). More recently, prophylaxis…
2018 American Transplant Congress
Is Age a Potential Barrier to Pursuing Living Donor Kidney Transplant (LDKT)?
A. Raissi, N. Edwards, Y. Liao, D. Belenko, N. Singh, M. Khalid, D. Toews, I. Mucsi.
Multi-Organ Transplant Program, Department of Surgery, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
BackgroundThe incidence of end stage kidney disease (ESKD) among older adults (65+) is increasing. Living Donor Kidney Transplant (LDKT) may provide improved outcome even for…
2018 American Transplant Congress
Combination Proteasome Inhibition and Anti-BAFF Therapy Permits Highly Sensitized Rhesus Kidney Transplantation
B. Ezekian, J. Kwun, M. Manook, P. Schroder, J. Yoon, M. Mulvihill, K. Freischlag, J. Park, J. Cochran, K. Kroning, J. Yi, S. Knechtle.
Duke Transplant Center, Duke University Medical Center, Durham, NC.
Purpose:HLA-sensitization is a significant immunologic barrier to successful kidney transplantation (KT). We have shown that proteasome inhibition (PI) in insolation reduces plasma cells (PCs), but…
2018 American Transplant Congress
Treatment of Active Chronic Antibody-Mediated Rejection with Rituximab, IVIG and Plasma Exchange
G. Piñeiro,¹ J. Rovira,² E. De Sousa-Amorim,¹ J. Villarreal,¹ M. Sole,³ I. Revuelta,¹ M. Lozano,⁴ E. Palou,⁴ F. Oppenheimer,¹ J. Campistol,¹ F. Diekmann.^1,2
¹Nephrology and Renal Transplantation, Hospital Clinic de Barcelona, Barcelona, Spain; ²Laboratori Experimental de Nefrologia i Trasplantament (LENIT), Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; ³Pathology, Hospital Clinic de Barcelona, Barcelona, Spain; ⁴Apheresis Unit, Hemotherapy and Hemostasis, Hospital Clinic de Barcelona, Barcelona, Spain; ⁵Immunology, Hospital Clinic de Barcelona, Barcelona, Spain.
Chronic antibody-mediated rejection (cABMR) and transplant glomerulopathy (TG) are main features associated with long-term graft loss. Despite its clinical significance, the available evidence on treatment…
2018 American Transplant Congress
Non-Medical Factors Predict Receipt and Type of Kidney Transplant in Veterans
K. Kendall, X. Li, C.-C. Chang, J. Pleis, E. Croswell, M. Dew, G. Switzer, A. Langone, A. Mittal-Henkle, S. Saha, M. Ramkumar, J. Adams-Flohr, C. Thomas, L. Myaskovsky.
VA Kidney Transplant Centers: IA, OR, PA, TN, Iowa City, Portland, Pittsburgh, Nashville.
Background: African Americans, Hispanic Americans and other minorities have a higher incidence of end-stage kidney disease but lower rates of both deceased and living donor…
2018 American Transplant Congress
The Influence of a Conversion to Sirolimus-Based Immunosuppression on Non-Melanomatous Skin Cancer Incidence in Kidney Transplant Recipients over Long Term Follow Up
F. Daly,¹ P. O'Kelly,¹ F. Moloney,² D. Sexton,¹ P. Conlon.¹
¹Department of Nephrology and Transplantation, Beaumont Hospital, Dublin, Ireland; ²Department of Dermatology, Mater Misericordiae University Hospital, Dublin, Ireland.
Background: The CONVERT trial found a reduced incidence of malignancy amongst renal transplant recipients over 2 years of follow up with a conversion from calcineurin…
2018 American Transplant Congress
Factor Analysis (FA) of Renal Transplant Biopsy (KTxBx) Data Enables Objective Assessment of Risk for Subsequent Death Censored Graft Failure (DCGF)
L. Hunsicker,¹ J. Grande,² J. Cecka,³ A. Matas,⁴ The DeKaf Consortium.
¹Int. Med., UIowa, Iowa City, IA; ²Pathology, Mayo Clinic, Rochester, MN; ³Immunogenetics, UCLA, Los Angeles, CA; ⁴Surgery, U Minnesota, Minneapolis, MN.
We examined the impact of five axes of injury identified by FA in the KTxBx on the hazard for subsequent DCGF in two DeKAF cohorts.Methods:…
2018 American Transplant Congress
Prevention of New Onset Diabetes after Transplantation Using Bariatric Surgery
A. Bailey, Y. Kim, S. Woodle, S. Shah, F. Paterno, M. Cuffy, T. Diwan.
Transplant Surgery, University of Cincinnati, Cincinnati, OH.
New onset diabetes after transplantation (NODAT) is a common complication, occurring 20-36% after renal transplant historically and 15.8% at our institution. Obesity is a known…
2018 American Transplant Congress
Using the Explore Transplant Ontario Program to Increase Transplant Knowledge and Readiness among Patients on Maintenance Dialysis
D. Belenko,¹ C. Richardson,¹ V. Gupta,¹ T. Ahmed, N. Edwards, M. Novak,² J. Peipert,³ A. Waterman, I. Mucsi.
¹Multi-Organ Transplant Program, Department of Surgery, University Health Network, Toronto, ON, Canada; ²Department of Psychiatry, University of Toronto, Toronto, ON, Canada; ³David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
IntroductionKidney transplantation (KT) is the preferred treatment for patients with End-Stage Kidney Disease (ESKD), yet many potentially eligible patients do not act to pursue KT.…