Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Failure to Remove De Novo Donor-Specific HLA Antibodies is Influenced by Antibody Properties and Identifies Kidney Recipients with Late Antibody-Mediated Rejection Destined to Graft Loss
A. Nocera,¹ M. Cioni,¹ A. Tagliamacco,² S. Basso,³ A. Innocente,⁴ I. Fontana,⁵ A. Magnasco,¹ A. Trivelli,¹ A. Gurrado,³ M. Ramondetta,⁴ S. Boghen,³ L. Catenacci,³ E. Verrina,¹ G. Garibotto,² G. Ghiggeri,¹ M. Cardillo,⁴ F. Ginevri,¹ P. Comoli.³
¹Pediatric Nephrology Unit, IRCCS G. Gaslini, Genova, Italy; ²Clinical Nephrology Unit, University of Genova, Genova, Italy; ³Transplant Immunology and Pediatric Hematology/Oncology, IRCCS Policlinico S. Matteo, Pavia, Italy; ⁴Transplantation Immunology, Ospedale Maggiore Policlinico, Milano, Italy; ⁵Kidney Transplant Surgery Unit, Ospedale Policlinico San Martino, Genova, Italy.
Late antibody-mediated rejection (AMR) is the major cause of renal allograft loss. Current research is focusing on identifying a performant risk stratification in order to…
2018 American Transplant Congress
Aggressive Pursuit of Donation after Cardiac Death Kidney Donors with High Kidney Donor Profile Index: Good Use of Resources?
J. Rogge, C. Hostetler, B. Nicely, S. Rudich.
Clinical Division, Gift of Life Michigan, Ann Arbor, MI.
Pursuit of donation after cardiac death (DCD) organ donors requires a significant investment in resources. As an Organ Procurement Organization which very aggressively pursues such…
2018 American Transplant Congress
Early Steroid Withdrawal or Tacrolimus Minimization versus Standard Immunosuppression in Renal Transplant Recipients: The Allegro Trial
J. Sanders,¹ A. Gomes-Neto,¹ M. v Dijk,¹ M. v Sandwijk,² H. de Fijter,³ J. Homan vd Heide,² A. de Vries,³ F. Bemelman.²
¹Nephrology, UMCG, Groningen, Netherlands; ²Nephrology, AMC, Amsterdam, Netherlands; ³Nephrology, LUMC, Leiden, Netherlands.
BackgroundCurrent immunosuppressive regimen in most renal transplant recipients (RTR) combines basiliximab induction with tacrolimus, mycophenolic acid and prednisolone maintenance therapy. Reduction of immunosuppression by withdrawal…
2018 American Transplant Congress
Clinical Significance of Tacrolimus Trough Level at the Early Period after Kidney Transplantation
W. Park,^1,2 S. Yeo,¹ S. Kang,^1,2 H. Park,¹ K. Jin,^1,2 S. Park,^1,2 S. Han.^1,2
¹Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea; ²Keimyung University Kidney Institute, Daegu, Republic of Korea.
Background:The stable immunosuppressant level at the early period after kidney transplantation (KT) is one of the most important factors to decide the prognosis of KT.…
2018 American Transplant Congress
Maternal and Fetal Outcomes in Living Kidney Donors in Korea
H. Lee,¹ K. Yoo,² M. Yu,¹ Y. Kim.¹
¹Seoul National University, Seoul, Korea; ²Dongguk University College of Medicine, Gyeongju, Korea.
Background. Mild elevation of blood pressure after unilateral nephrectomy may contribute to elevate gestational hypertension or preeclampsia in women donors. To date, impact of kidney…
2018 American Transplant Congress
Native Kidney Volume Decreases after Kidney Transplantation in Patients with Autosomal Dominant Polycystic Kidney Disease: Less Patients Need Nephrectomy?
R. Murakami,¹ D. Nagawa,¹ M. Nakata,¹ I. Narita,¹ T. Fujita,¹ M. Shimada,¹ N. Nakamura,¹ H. Tomita,¹ S. Hatakeyama,² T. Yoneyama,² Y. Hashimoto,² T. Koie,² C. Ohyama.²
¹Nephrology, Hirosaki University, Hirosaki, Japan; ²Urology, Hirosaki University, Hirosaki, Japan.
Background.The clinical implication of kidney volume decline on abdominal symptom improvement after kidney transplantation in patients with autosomal dominant polycystic kidney disease (ADPKD). We investigated…
2018 American Transplant Congress
Artificial Graft Extension of Renal Vein in Living Kidney Transplantation
S. Cho,¹ W. Cho,¹ M-.J. Cho,¹ C. Choi,¹ S. Ahn,¹ S-.I. Min,¹ S-.K. Min,¹ S. Kim,² J. Ha.¹
¹General Surgery, Seoul National University Hospital, Seoul, Korea; ²General Surgery, Myongji Hospital, Goyang, Korea.
Background. The recovered kidney sometimes has a renal vein short in length for a satisfactory anastomosis or in some cases the vein can be damaged…
2018 American Transplant Congress
Long-Term Prognosis of BK Virus Associated Nephropathy in Kidney Transplant Recipients
W. Park,^1,3 S. Yeo,¹ S. Kang,^1,3 H. Park,¹ K. Jin,^1,3 S. Park,^1,3 M. Choe,^2,3 S. Han.^1,3
¹Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea; ²Pathology, Keimyung University School of Medicine, Daegu, Republic of Korea; ³Keimyung University Kidney Institute, Daegu, Republic of Korea.
Background: BK virus-associated nephropathy (BKVAN) is an important risk factor that results in an allograft loss in kidney transplant recipients (KTRs). The short-term prognosis of…
2018 American Transplant Congress
HIV-Positive Donors to HIV-Positive Transplant Recipients: The Italian Experience
P. Grossi,¹ D. Dalla Gasperina,¹ A. Petrolo,¹ D. Lombardi,¹ M. Balsamo,¹ M. Moioli,² G. Travi,² M. Merli,² F. Ferla,² M. Tozzi,¹ L. De Carlis,² G. Carcano,¹ M. Puoti,² A. Nanni Costa.³
¹Medicine and Surgery, University of Insubria-ASST Sette Laghi, Varese, Italy; ²ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ³Centro Nazionale Trapianti-ISS, Roma, Italy.
In order to expand the availability of organs for HIV-positive patients, successful transplantation of kidneys and livers from HIV-positive donors into selected HIV-positive recipients was…
2018 American Transplant Congress
Mycophenolic Acid Reduces BK Polyomavirus Replication in an In Vitro Model of Renal Tubular Epithelial Cells Infection
E. Favi,¹ S. Delbue,² C. Colico,¹ P. Ferrante,² S. Villani,² I. Perna,² N. Mondoni,² A. Giussani,¹ M. Ferraresso.¹
¹Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; ²Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Background. BK virus (BKV) nephropathy is an important cause of allograft failure after kidney transplant. Immunosuppression is a recognized risk factor for BKV replication but…