Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Pegloticase Use in Renal Transplant Recipients with Gout: Findings from an Insurance Claims Database Study
C. A. Shadur¹, B. Marder², C. Vesel², B. LaMoreaux²
¹Iowa Kidney Physicians, Des Moines, IA, ²Horizon Therapeutics plc, Deerfield, IL
*Purpose: Kidney transplant (KT) recipients have high gout incidence due to reduced eGFR and medication use associated with hyperuricemia.1 Oral urate-lowering therapies in KT patients…
2022 American Transplant Congress
The Impact of Maintenance Immunosuppressive Regimen on COVID-19 Outcomes Among Kidney Transplant Patients
T. V. Sandes-Freitas¹, L. Modelli de Andrade², L. Requião-Moura³, J. Medina-Pestana³, H. Tedesco-Silva³, A. on behalf of Covid-19 KT Brazil Study Group¹
¹Universidade Federal do Ceará / Unidade Pesquisa Clínica CH-UFC/EBSERH, Fortaleza, Brazil, ²Universidade Estadual Paulista - UNESP, Botucatu, Brazil, ³Universidade Federal de São Paulo / Hospital do Rim, São Paulo, Brazil
*Purpose: Compared to azathioprine (AZA), mycophenolate (MPA) is implicated in an increased risk of several viral infections. Contrariwise, mTOR inhibitors (mTORi) are protective. Therefore, the…
2022 American Transplant Congress
Time-Dependent Blood Eosinophilia Count Increases the Risk of Kidney Allograft Rejection
L. Colas¹, L. Bui², C. Kerleau³, M. Lemdani⁴, K. Autain-Renaudin⁵, A. Magnan⁶, M. Giral³, S. Brouard¹
¹CRT2I, Université de Nantes, Nantes, France, ²Service de Néphrologie, Centre Hospitalier de Mouscron, Mouscron, Belgium, ³Service de Néphrologie et Immunologie Clinique, CHU de Nantes, Nantes, France, ⁴Département de Biomathématiques, Université de Lilles, Lilles, France, ⁵Service d'Anatomie et Cytologie Pathologique, CHU de Nantes, Nantes, France, ⁶INRAe UMR 0892, Université de Versailles Saint-Quentin Paris-Saclay, Paris, France
*Purpose: There is growing evidence that type 2 immune effectors (immunoglobulin E, eosinophils, mast cells/basophils) play a role in autoimmune disorders and solid organ transplantation.…
2022 American Transplant Congress
Donor Disposition AI Model to Predict Transplant for Recovered Deceased Donor Kidneys
L. Ashiku¹, R. Threlkeld¹, C. Dagli¹, M. Schnitzler², C. Canfield¹, K. Lentine², H. Randall²
¹MST, Rolla, MO, ²SLU, Saint Louis, MO
*Purpose: Current practice for accelerated kidney placements rely heavily on the Kidney Donor Profile Index (KDPI) to determine if recovered deceased-donor (DD) kidneys are hard-to-place.…
2022 American Transplant Congress
Outcomes of Kidney Transplant Recipients with Covid-19 in Singapore Treated with Sotrovimab in the Era of the Delta Variant
M. R. D'Costa¹, H. K. Sran¹, E. Wong¹, Z. Chang², Y. Chua², J. Somani³, L. Lum³, A. Vathsala¹
¹National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore, ²Medicine, National University Hospital, Singapore, Singapore, ³Infectious Diseases, National University Hospital, Singapore, Singapore
*Purpose: Kidney transplant recipients (KTRs) are at higher risk for severe COVID-19 caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Sotrovimab decreases the risk…
2022 American Transplant Congress
Pump Resistance Thresholds and Graft Outcomes in Machine Perfused Kidneys-A Single Center Retrospective Study
S. Sivan, J. Gaynor, M. Tabbara, G. Ciancio
Univ of Miami Miller School of Medicine, Miami, FL
*Purpose: Perfusion parameters are increasingly used to assess the quality of organs and to make decisions about discarding the organ. Resistive index(RI) has been an…
2022 American Transplant Congress
Why and How We Do Native Nephrectomy in Low Weight Pediatric Kidney Transplantation Patients
N. Celik¹, B. Akyollu¹, E. Arpali¹, N. Akinci², I. Bilge², B. Kocak¹
¹Division of Organ Transplantation, Koc University Hospital, Istanbul, Turkey, ²Division of Pediatric Nephrology, Koc University Hospital, Istanbul, Turkey
*Purpose: There is no consensus about optimal timing for native nephrectomy according to the primary indication of kidney transplantation (KTx) especially in pediatric population and…
2022 American Transplant Congress
Covid-19 Vaccination Response In Tacrolimus Treated Kidney Transplant Recipients With And Without Mycophenolate Mofetil: Follow-up Of A Randomized Controlled Trial
Z. Al Fatly¹, M. G. Betjes¹, A. L. Messchendorp², J. S. Sanders², M. E. Reinders¹, M. M. Kho¹, A. E. de Weerd¹
¹Department of Internal Medicine, Erasmus MC Transplant Institute University Medical Center, Rotterdam, Netherlands, ²Department of Internal Medicine, Groningen Medical Center, Groningen, Netherlands
*Purpose: To investigate the effect of mycophenolate mofetil (MMF) on SARS-CoV-2 vaccination response in kidney transplant recipients using the standard immunosuppressive regimen of tacrolimus (TAC)…
2022 American Transplant Congress
Sodium-Glucose Co-Transporter 2 Inhibitors; Short-Term Outcome in Diabetic Kidney Transplant Recipients
J. Yagan¹, T. S. Mahmoud¹, A. Hasan², O. Gheith¹, n. El-Serwy¹, S. Rida¹, M. Mostafa¹, M. Shaker¹, P. Nair¹, T. Alotaibi¹
¹Nephrology, Hamed Al-Essa Organ Transplant Center, Kuwait, Kuwait, ²Immunometabolism, Dasman Diabetes Center, Kuwait, Kuwait
*Purpose: The idea of using SGLT2i in kidney transplant recipients (KTR) is a legitimate one after the recent encouraging data for their use in other…
2022 American Transplant Congress
Establishment And Validation Of A Predictive Model For Differential Rejection Diagnosis By Gene Expression Profiling (GEP) In Renal Allograft Biopsies Using Banff Human Organ Transplant (B-HOT) Gene Panel
H. Zhang¹, R. Haun², F. Collin¹, C. Cassol², S. Coley², J. Wilson², S. Stone¹, K. Qu¹, W. Tian¹, N. Agrawal¹, G. Shekhtman¹, C. Larsen²
¹CareDx, Inc., Brisbane, CA, ²Arkana Laboratories, Little Rock, AR
*Purpose: Large scale GEP studies evaluating the performance of Banff-endorsed B-HOT gene panel for allograft rejection diagnosis have not been published. In this study, we…