Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Reduced Ratio of FoxP3/ RORγt Gene Expression, in Peripheral Blood, is Associated with Acute Allograft Rejection in Recipients with Kidney Transplantation
R. Dhital,^1,2 R. Minz,³ M. Minz,^1,4 A. Sharma,¹ R. Nada,⁵ S. Singh,¹ D. Kenwar,¹ S. Anand.³
¹Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; ²Vaccines and Immunity, Nationwide Children's Hospital, Columbus, OH; ³Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; ⁴Organ Transplantation, Fortis Hospital, Mohali, Punjab, India; ⁵Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India.
Introduction:FoxP3 has been well established as an indispensable protein that is required in the development and function of regulatory T cells. On the other hand,…
2018 American Transplant Congress
Identifying Patients with CPRA>99.95% Likely to Be Offered Deceased Donor Kidneys
R. Parsons, S. Bumb, H. Decker, R. Bray, H. Gebel.
Emory Transplant Center, Atlanta, GA.
The implementation of the new kidney allocation system and priority of kidneys for cPRA=100% subjects revealed a hierarchy difference in allocation to patients with cPRA=99.45%-100%.…
2018 American Transplant Congress
Is KDPI Valid for Hepatitis C Aviremic Kidneys?
L. Sibulesky,¹ C. Kling,¹ C. Blosser,² C. Johnson,² A. Limaye,² R. Bakthavatsalam,¹ N. Leca,² J. Perkins.¹
¹Surgery, University of Washington Medical Center, Seattle, WA; ²Medicine, University of Washington Medical Center, Seattle, WA.
KDRI is an estimate of post-transplant kidney graft failure. It is based on ten donor factors that independently affect transplant outcomes, including HCV status from…
2018 American Transplant Congress
Potential Living Donors Identified through Social Media
S. Weeks, K. Kumar, J. Konel, E. King, M. Henderson, A. Cameron, J. Garonzik Wang.
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…
2018 American Transplant Congress
Transplanting Kidneys from HCV-Infected Donors into HCV-Negative Recipients: Longer-Term and Extended Results of the THINKER Trial
D. Goldberg,¹ E. Blumberg,¹ P. Abt,¹ M. Levine,¹ P. Porrett,¹ A. Naji,¹ S. Nazarian,¹ D. Sawinski,¹ J. Trofe-Clark,¹ V. Van Deerlin,¹ C. Gentile,¹ J. Smith,¹ M. Kaminski,¹ A. Sicilia,¹ R. Hasz,² L. Suplee,² R. Reddy,¹ R. Bloom,¹ P. Reese.¹
¹University of Pennsylvania, Philadelphia; ²Gift of Life, Philadelphia.
Background: In 2016, 800 kidneys from HCV+ deceased donors were discarded. Short-term (6-month) data from the first 10 subjects in the THINKER-1 trial (NCT02743897; funder:…
2018 American Transplant Congress
Disparity in Access to Kidney Allograft Offers among HIV+ Transplant Candidates
J. Cohen,¹ J. Locke,² B. Shelton,² R. Reed,² P. MacLennan,² D. Sawinski.¹
¹Renal Division, University of Pennsylvania, Philadelphia, PA; ²Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Background: Despite having a demonstrated survival benefit with kidney transplantation, patients with chronic viral infections, such as HCV or HIV, face many barriers to transplantation,…
2018 American Transplant Congress
Comparing Outcomes between Induction Immunosuppressive Therapies in Simultaneous Heart/Kidney Transplantation
I. Moinuddin, J. Yu, L. Kang, C. Bhati, D. Bandyopadhyay, A. King, D. Kumar, L. Kamal, D. Tang, I. Yakubu, G. Gupta.
Virginia Commonwealth University, Richmond.
Introduction: There is no published data on the risks and benefits of Induction immunosuppression in simultaneous heart/kidney transplant (SHKT) patients.Methods: We analyzed all SHKT performed…
2018 American Transplant Congress
Inflammation in Scarred Areas (I-IFTA) is a Reflection of Parenchymal Injury (Response to Wounding) Not T Cell-Mediated Rejection
P. Halloran, J. Chang, K. Famulski.
Medicine, University of Alberta, Edmonton, AB, Canada.
Inflammation in fibrotic renal parenchyma (i-IFTA) is associated with decreased graft survival but by Banff rules is not diagnostic for rejection. Some researchers believe that…
2018 American Transplant Congress
Quality of Social Support Network and Access to Transplant: What Matters?
A. Waterman,^1,2 J. Beaumont,² S. Kawakita,² M. Dunbar-Forest,¹ G. Danovitch,¹ I. Hong,¹ C. Anderson,¹ M. Everly,^1,2 J. Peipert.^1,2
¹Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; ²Terasaki Research Institute, Los Angeles, CA.
Recovery after kidney transplant (KT) requires adequate social support. Caregivers are asked to attend transplant evaluation and complete a caregiver contract. Little is known about…
2018 American Transplant Congress
Burden of Infectious Complications after Upper Extremity Allotransplantation: A Matched Cohort Study
A. Conrad,^1,2,3 P. Petruzzo,^4,5 J. Kanitakis,⁶ A. Gazarian,⁷ L. Badet,^3,8 P. Vanhems,^3,9 O. Thaunat,^1,3,10 E. Morelon,^1,3,10 A. Sicard.^1,3
¹Department of Transplantation, Nephrology and Clinical Immunology, Hospices Civils de Lyon (HCL), Lyon, France; ²Department of Infectious Diseases and Tropical Medicine, HCL, Lyon, France; ³Claude Bernard Lyon 1 University, Lyon, France; ⁴Department of Transplantation, HCL, Lyon, France; ⁵Department of Surgery, University of Cagliari, Cagliari, Italy; ⁶Department of Dermatology, HCL, Lyon, France; ⁷Clinique du Parc, Lyon, France; ⁸Department of Urology and Transplantation, HCL, Lyon, France; ⁹Infection Control and Epidemiology Unit, HCL, Lyon, France; ¹⁰INSERM U1111, International Center for Infectiology Research, Lyon, France.
This study aimed to assess the infectious risk after upper extremity allotransplantation (UEA), a non-vital transplantation procedure requiring lifelong immunosuppression. A matched cohort study was…