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American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2018 American Transplant Congress

    Renal Function, Blood Pressure, and Histologic Changes in Living Kidney Transplant Recipients from Hypertensive Donors

    T. Dienemann, J. Schellenberg, K. Amann, K. Heller, A. Weidemann.

    Nephrology and Hypertension University Hospital Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany.

    Little is known if a kidney from a hypertensive donor performs equally compared to a kidney from a non-hypertensive donor. The present study examines the…
  • 2018 American Transplant Congress

    The Benefit of Higher KDPI Renal Transplantation over Waiting for a Better Offer

    E. Grodstein,1 J. Yang,2 V. Nair,1 E. Molmenti,1 L. Teperman.1

    1Transplant Institute, Northwell Health, Manhasset, NY; 2Department of Epidemiology, Northwell Health, Manhasset, NY.

    Background: The kidney donor profile index (KDPI) helps discern kidney function. While recipients must consent for KDPI >85% kidneys, clinicians often decide whether to accept…
  • 2018 American Transplant Congress

    Clinical Outcomes of Patients with BK Viremia in ABO-Incompatible Kidney Transplantation and Comparison with ABO-Compatible Kidney Transplantation

    J. Yoon, C. Baek, S-.K. Park, H. Kim.

    Internal Medicine, Asan Medical Center, Seoul, Republic of Korea.

    Background and Aim:ABO-incompatible kidney transplantation (ABOiKT) recipients may have an increased risk of BK virus allograft nephropathy (BKVAN), a major cause of renal dysfunction and…
  • 2018 American Transplant Congress

    B Cell Immune Repertoire Sequencing Identifies Pre-Transplant Rejection Risk

    S. Pineda,1,2 T. Sigdel,1 J. Liberto,1 K. Roskin,3 S. Robin,3 M. Sirota,2 M. Sarwal.1

    1Surgery, UCSF, SF; 2ICHS, UCSF, SF; 3Pathology, Stanford, Stanford.

    Background: The diversity of the B cell immune repertoire may drive humoral injury and rejection in organ transplantation (tx).Methods: We utilized advances in next-generation sequencing…
  • 2018 American Transplant Congress

    Decreased Long-Term Survival with Antithymocyte Globulin Induction in Elderly Kidney Transplant Recipients

    I. Bajjoka, A. Yaldo, C. Crombez, M. Abouljoud.

    Henry Ford Transplant Institute, Detroit, MI.

    Purpose: Long-term consequences of immunosuppression on the elderly is still unclear. This data to evaluates long-term outcomes for younger (Y) versus elderly (E) kidney transplant…
  • 2018 American Transplant Congress

    Exercise Rehabilitation's Effect on Employment and School Rates in Kidney Transplant Patients

    A. Kastelz,1,2 C. Di Bella,1 I. Tzvetanov,1 B. Fernhall,2 L. Gallon,3 G. Hachaj,4 E. Benedetti.1

    1Surgery, University of Illinois, Chicago, IL; 2Integrative Physiology Lab, University of Illinois, Chicago, IL; 3Internal Medicine Nephrology, Northwestern Medical Group, Chicago, IL; 4GH FitLab, Chicago, IL.

    Unemployment after kidney transplant is common and creates a heavy reliance on public aid. While the exact reason for low employment rates is unknown, patients…
  • 2018 American Transplant Congress

    “Majority Rules”: A Method to Reduce Variability in Diagnosing Antibody Mediated Rejection in Renal Allograft Biopsies Using Banff 2013

    B. Smith,1 L. Cornell,1 M. Smith,2 C. Cortese,3 X. Geiger,3 C. Schinstock,1 W. Kremers,1 M. Stegall.1

    1Mayo Clinic, Rochester, MN; 2Mayo Clinic, Scottsdale, AZ; 3Mayo Clinic, Jacksonville, FL.

    Introduction: The Banff 2013 criteria for diagnosing antibody-mediated rejection (ABMR) includes three lesions: glomerulitis (g), peritubularitis (PTC), and chronic glomerulopathy (cg). The poor reproducibility of…
  • 2018 American Transplant Congress

    Population-Based Modeling of Prototypes and Determinants of Allograft Function Trajectories after Kidney Transplantation: Implications for Patient Monitoring and Risk Stratification

    M. Raynaud, O. Aubert, M. Naessens, E. Morelon, M. Giral, N. Kamar, E. Wong, S. Jordan, B. Orandi, D. Segev, M. Stegal, P. Reese, C. Lefaucheur, A. Loupy.

    Paris Transplant Group, Paris, France.

    Background:Although the current gold standard of monitoring kidney allograft patients relies primarily on GFR assessment, little is known about long-term eGFR trajectories prototypes and their…
  • 2018 American Transplant Congress

    The Effect of Perioperative Antiplatelet/Anticoagulant Therapy on the Incidence of Early Postoperative Thromboembolic Complications and Bleeding in Kidney Transplantation – A Dual Center Retrospective Cohort Study of 2000 Kidney Transplant Recipients

    T. van den Berg,1 R. Minnee,2 G. Nieuwenhuijs-Moeke,3 S. Bakker,4 R. Pol.1

    1Department of Surgery, University Medical Center Groningen (UMCG), Groningen, Netherlands; 2Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; 3Department of Anesthesiology, UMCG, Groningen, Netherlands; 4Department of Internal Medicine-Nephrology, UMCG, Groningen, Netherlands.

    Thromboembolic complications (TECs) are dreaded complications after kidney transplantation (KTx). Consequences are severe and can result in delayed graft function or even graft loss. Perioperative…
  • 2018 American Transplant Congress

    CFZ533, a New Anti-CD40 mAB Demonstrates Comparable Efficacy and Better Renal Function versus Tacrolimus in De-Novo CNI-Free Kidney Transplantation

    B. Nashan,1 H. Tedesco,1 M. van den Hoogen,1 S. Berger,1 D. Cibrik,1 S. Mulgaonkar,1 D. Leeser,1 R. Alloway,1 A. Patel,1 J. Pratschke,1 C. Sommerer,1 A. Wiseman,1 A. van Zuilen,1 U. Laessing,2 J. Rush,2 B. Haraldsson,2 O. Witzke.1

    1CFZ533 Study Group, Basel, Switzerland; 2Novartis Pharma, Basel, Switzerland.

    Purpose: To assess the potential of CFZ533 as primary immunosuppressant in a calcineurin(CNI)-free regimen in de novo kidney transplant (KTx) patients(pts).Method: CFZ533 is a new,…
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