2018 American Transplant Congress
Unique Recipient Benefits with Paired Kidney Donation
Introduction: Kidney transplantation is the treatment choice for ESRD with improved survival and cost benefit compared with dialysis. The imbalance of supply over demand along…2018 American Transplant Congress
Evaluation of Allergy to Tacrolimus in Kidney Transplant Candidates and Recipients with a History of Macrolide Antibiotic Allergy
Background: Tacrolimus (TAC) is considered a drug of choice for maintenance immunosuppression among kidney transplant (KTX) recipients. Because of structural resemblances between macrolide antibiotics (azithromycin,…2018 American Transplant Congress
Metabolic Complications 10-Years after Kidney Transplant
Background: Improving long-term outcomes is an important but unmet need after kidney transplant. Protocol renal allograft biopsies taken 10-years after transplant frequently show diabetic nephropathy…2018 American Transplant Congress
Measures of Physical Frailty, Cardiac Function and Cardiac Biomarkers among Kidney Transplant Candidates
1Intermountain Medical Center, Murray, UT; 2University of Utah, Salt Lake City, UT.
Background: Elevated troponin T at transplant evaluation has been reported to confer risk of cardiovascular mortality among renal transplants. We use troponin T along with…2018 American Transplant Congress
Predictors of Early Graft Loss in Older Kidney Transplant Recipients
Medical University of South Carolina, Charleston, SC.
Older kidney transplant recipients are vulnerable to early graft loss likely due to frailty and burden of comorbidities. Other factors not inherent to the recipient…2018 American Transplant Congress
The Role of pDCs in Formation of Treg-Rich Organized Lymphoid Structures in Spontaneously Accepted Murine Kidney Allografts is Dependent on Mismatching of MHC Class II Molecules at the H2-I-Ab Locus
Introduction: Our lab has demonstrated that murine kidney allografts are spontaneously accepted in specific donor-recipient strain combinations. Histologic examination of spontaneously accepted DBA/2J (DBA) kidneys…2018 American Transplant Congress
The Brazilian Epitope Virtual Crossmatch Protocol: A Reliable Tool for Increasing Kidney Allocation among Highly Sensitized Patients
Background: In Brazil (BZ), the kidney allocation policy for highly sensitized patients (HS) (PRA ≥ 80%) does not involve prioritization and transplants 10 times less…2018 American Transplant Congress
Many Highly Sensitized Candidates Still Waiting for Transplant Despite the Kidney Allocation System Change: Making the Case for Incompatible Transplantation
Introduction: The rate of kidney transplantation in highly sensitized individuals has increased since the kidney allocation system (KAS) change, but it remains unclear who has…2018 American Transplant Congress
Effect of rATG on Monocytic Myeloid-Derived Suppressor Cells and Its Associated Mechanisms in Kidney Transplantation Recipients
Beijing Chao-Yang Hospital, Beijing, China.
Myeloid-derived suppressor cells (MDSCs) consist of heterogeneous myeloid progenitors and precursors that was first defined in cancer patients and are characterized by a regulatory ability…2018 American Transplant Congress
Thymoglobulin Dose and Effect on Short-Term Kidney Transplant Outcomes
University of Pitstburgh Medical Center, Pittsburgh.
Thymoglobulin is a commonly used induction agent for kidney transplantation. Optimal dosing for thymoglobulin is not well defined, and weight based dosing is often used.…
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