Articles tagged "Kidney transplantation"

2018 American Transplant Congress
What Deceased Donors Do KPD Candidates Accept?
A. Toll,¹ R. Leishman,¹ V. Casingal,² M. Aeder,³ T. Sandholm,⁴ N. Turgeon.⁵
¹UNOS, Richmond, VA; ²Carolinas HealthCare Sys, Charlotte, NC; ³Univ Hosp Med Ctr, Cleveland, OH; ⁴Carnegie Mellon Univ, Pittsburgh, PA; ⁵Emory Univ, Atlanta, GA.
Background: Possible utilization of deceased donors (DDs) to initiate KPD chains has been of interest to the transplant community. OPTN KPD candidates are required to…
2018 American Transplant Congress
Genome Wide Non-HLA Alloimmunity Contributes to Graft Loss after Kidney Transplantation
R. Reindl-Schwaighofer, A. Heinzel, A. Kainz, K. Jelencsics, O. Viklicky, G. Böhmig, G. Fischer, B. Keating, R. Oberbauer.
Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; Transplant Institute, University of Pennsylvania, Philadelphia, PA.
BackgroundChronic rejection is the main cause of renal transplant loss after the first year and has mostly been attributed to alloimmune responses against human leukocyte…
2018 American Transplant Congress
Enhancing Coordination across Healthcare Settings through a Web-Based Transplant Referral Exchange (T-REX) Platform
L. McPherson,¹ R. Mutell,² P. Broughton,² M. Basu,¹ J. Gander,¹ S. Pastan,¹ R. Patzer.¹
¹Emory University, Atlanta, GA; ²Apex Health Innovations, Simi Valley, CA.
Background: Communication between dialysis and transplant centers with regard to end-stage renal disease patient information throughout the transplant process is administratively intensive. We collaborated with…
2018 American Transplant Congress
T cell Phenotypes Predict Infectious Risk in Transplanted Children
E. T. Chambers,¹ R. Ettenger,² H.-J. Lee,¹ C. Chan,¹ L. Stempora,¹ B. Warshaw,³ P. Grimm,⁴ E. F. Reed,² M. Sarwal,⁵ A. Kirk.¹
¹Pediatrics/Surgery, Duke University, Durham; ²Pediatrics, UCLA, Los Angeles; ³Pediatrics, Emory, Atlanta; ⁴Pediatrics, Stanford, Palo Alto; ⁵Surgery, UCSF, San Francisco.
AIM: Current monitoring strategies do not adequately differentiate infection from complications such as allograft rejection (AR). We aimed to identify peripheral T cell phenotypes that…
2018 American Transplant Congress
IgM HLA DSAs Do Not Alter the Outcomes of Renal Allograft Rejection
A. Gueret-Wardle,¹ P. Dodd,¹ G. Lucisano,¹ S. Hassan,¹ P. Brookes,² E. Santos-Nunez,² N. Firmin,² D. Goodall,¹ C. Roufosse,¹ M. Willicombe,¹ D. Taube.¹
¹Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ²Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom.
Introduction: whilst IgG HLA DSAs are associated with renal allograft rejection and graft loss, the role of IgM HLA DSAs is controversial. We investigate the…
2018 American Transplant Congress
Defining Response to Standard of Care Treatment in Kidney Recipients with Antibody-Mediated Rejection: Role of C1q-Binding Donor-Specific Anti-HLA Antibodies
Y. Bouatou, D. Viglietti, O. Aubert, A. Loupy, C. Lefaucheur.
Paris Translational Research Center for Organ Transplantation, Paris, France.
A major hurdle to improving clinical care in kidney transplantation is the lack of biomarkers of the response to antibody-mediated rejection (ABMR) treatment. We investigated…
2018 American Transplant Congress
Comparison of C1Q Binding and Flow Cytometric Crossmatch Results Provides an Accurate Evaluation of Hypersensitive Kidney Transplant Patients
E. Eksioğlu-Demiralp,¹ A. Türkmen,² B. Yelken,² S. Görçin,² O. Elbasi,¹ F. Yalçin,³ B. Koçak,² C. Karatas,⁴ M. Tuncer,⁴ M. Altinel.³
¹Tissue Typing and Immunology Laboratory, Memorial Health Group, Istanbul, Turkey; ²Sisli Hospital Transplantation Unit, Memorial Health Group, Istanbul, Turkey; ³Hizmet Hospital Transplantation Unit, Memorial Health Group, Istanbul, Turkey; ⁴Atasehir Hospital Transplantation Unit, Memorial Health Group, Istanbul, Turkey.
Measurement of C1q binding to Donor specific antibodies (DSA) gives transplantation chance to hypersensitive patients having non-binding high amount of anti-HLA antibodies. In our series…
2018 American Transplant Congress
Delayed Graft Function in Live Donor HLA-Incompatible Kidney Transplant Recipients: A Multicenter Study
J. Motter,¹ A. Massie,¹ J. Garonzik Wang,¹ K. Jackson,¹ X. Luo,¹ A. Muzaale,¹ B. Orandi,² D. Segev.¹
¹JHU, Baltimore; ²UCSF, San Francisco.
Background: Many patients with a willing, but incompatible live donor choose to undergo incompatible live donor kidney transplantation (ILDKT) facilitated by desensitization procedures to eliminate…
2018 American Transplant Congress
Integration of Blood Type Incompatibility Desensitization Protocols into Kidney Paired Donation (KPD) Programs
F. Karami,¹ M. Nayebpour,² M. Gentili,¹ N. Koizumi,² K. Melancon.³
¹Industrial Engineering, University of Louisville, Louisville, KY; ²Schar School of Policy and Government, George Mason University, Arlington, VA; ³Department of Surgery, George Washington University Hospital, Washington DC.
Even if blood type incompatibility (ABOi) is one of the most significant barriers in transplantation, recent studies report that the outcomes of ABOi transplants with…
2018 American Transplant Congress
Retrospective Study of Cryptococcosis in Kidney Transplant Recipients from a Single Center
R. Wang, M. Cen, J. Lin, H. Huang, W. Peng, J. Wu.
Kidney Disease Center, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China.
Background: The mortality of Cryptococcosis remains unchanged among kidney transplant recipients(KTR) over the past two decades, and the prognosis of Cryptococcosis is yet unpredicted. Hence,…