2018 American Transplant Congress
Impact of Renal Parenchymal Calcifications in a Cohort of Renal Transplanted Patients and Their Correlations with Long Term Graft Outcome
Background: Renal calcifications(RC) have been described in kidney transplantation(KTx), but the aetiologyand significance of this finding are still unclear. Our aim is to evaluate the…2018 American Transplant Congress
Using the Remuzzi Score to Guide Single vs. Dual Transplantation Mitigates the Risk of Early Graft Failure
Surgery, University of Cambridge, Cambridge, United Kingdom.
BackgroundExpanded criteria circulatory death donors (DCD) may represent an underutilised donor pool. Our centre has used urgent pre-implantation biopsy (Remuzzi score) to guide single (SKT)…2018 American Transplant Congress
Microbiology and Outcomes of Febrile Neutropenia Episodes after Kidney Transplant
Medicine, Columbia University Medical Center, New York, NY.
Febrile neutropenia (FN) is a common complication in cancer patients receiving chemotherapy. Neutropenia is common after kidney transplant (KT), but little is known about the…2018 American Transplant Congress
Serum Beta-(1,3)-D-Glucan as a Case-Finding Tool during an Outbreak of Pneumocystitis jirovecii Pneumonia in Abdominal Transplant Patients
Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY.
Background: Pneumocystis jirovecii pneumonia(PJP) in solid organ transplant (SOT) recipients carries significant morbidity and mortality. There is mounting evidence for ongoing risk of PJP in…2018 American Transplant Congress
Highly Correlative Whole-Tissue Gene/protein Signatures to Score FFPE Transplant Biopsies with Inflammation and Acute Rejection
Unversity of California San Francisco, San Francisco.
Background: We have previously reported the quantification of a common immune response module (CRM) of 11 genes to identify and score acute rejection (AR) across…2018 American Transplant Congress
Prophylaxis of Wound Infections- Antibiotics in Renal Donation (POWAR): A Multicentre UK Double Blinded Placebo Controlled Randomised Controlled Trial
Abdominal Transplant Unit, Guy's Hospital, London, United Kingdom.
AIM: Postoperative infection following hand assisted laparoscopic donor nephrectomy (HALDN) confers significant morbidity. Previous reports suggest 1 in 5 patients develop infective complications. No modifiable…2018 American Transplant Congress
Anti-Angiotensin II Type 1-Receptor Antibodies (AT1R-Ab) Induce a Specific Phenotype of Rejection Distinct from HLA Antibody-Mediated Rejection
AT1R-Ab have been associated with kidney allograft rejection; however, their ability to induce a specific rejection phenotype, independent of HLA-DSAs, has not been defined.In a…2018 American Transplant Congress
Effect of Early Attainment of Everolimus Target Trough Levels on Efficacy-Safety Outcomes in De Novo Kidney Transplant Recipients: 12-Month Results from US92 and TRANSFORM Studies
Purpose: Attainment of everolimus (EVR) target trough level (C0 3-8ng/mL) is crucial in achieving comparable efficacy-safety with EVR+reduced (r) calcineurin inhibitor regimen (CNI; tacrolimus [TAC]…2018 American Transplant Congress
Kidney Transplant Rejection is Associated with Robust and Prolonged Bioenergetic Reprogramming and Metabolic Maladaptation
Medicine, University of Alabama at Birmingham, Birmingham, AL.
Introduction: Metabolic plasticity and mitochondrial bioenergetic homeostasis are altered due to a organ ischemia. However, the impact of the alloimmune response on the allograft is…2018 American Transplant Congress
Belatacept in Kidney Transplant Recipients with Preformed Donor Specific Anti-HLA Antibodies: Results of the BELACOR Trial
IntroductionAntibody-mediated rejection (ABMR) is currently a critical question in kidney transplant recipient with immunological risk factors such as pre transplant donor-specific anti HLA antibodies (DSA).…
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