Articles tagged "Kidney transplantation"

2018 American Transplant Congress
Outcomes after Kidney Transplantation in Patients with AL Amyloid Following Autologous Stem Cell Transplantation
V. Gutgarts,^1,2 I. Jaffer Sathick,² C. Rosenbaum,³ T. Muthukumar,¹ H. Hassoun,⁴ C. Flombaum,² H. Landau.⁴
¹Nephrology, Weill Cornell, NY; ²Renal Medicine, Memorial Sloan Kettering, NY; ³Hematology, Weill Cornell, NY; ⁴Hematology, Memorial Sloan Kettering, NY.
BackgroundAL amyloidosis results in kidney failure in about 15-30% of patients and is considered a relative contraindication for kidney transplantation. There is limited data on…
2018 American Transplant Congress
Impact of Steroid Maintenance on the Outcomes of HLA-DR Mismatch Kidney Transplantation
B. Chopra, K. Sureshkumar.
Allegheny General Hospital, Pittsburgh, PA.
In kidney transplantation, donor-recipient HLA-DR mismatch poses high immunologic risk and is associated with inferior outcomes. We aimed to explore the impact of enhanced immunosuppression…
2018 American Transplant Congress
Calcineurin Inhibitors, Macrolides, and the Risk of Adverse Drug Events in Kidney Transplant Recipients
R. Jeong,¹ R. Quinn,² P. Ravani,² K. Lentine,³ A. Lloyd,¹ B. Hemmelgarn,² K. Wen,¹ B. Braam,¹ S. Gourishankar,¹ A. Wong,¹ N. Lam.¹
¹Univ of Alberta, Edmonton, Canada; ²Univ of Calgary, Calgary, Canada; ³Saint Louis Univ, St. Louis.
Background: After kidney transplantation, calcineurin inhibitors (CNIs, cyclosporine, tacrolimus) are key components of immunosuppression but have multiple potential drug interactions. Macrolide antibiotics are often used…
2018 American Transplant Congress
South Asian and Muslim Canadian Patients Are Less Likely to Receive Living Donor Kidney Transplant Offers Compared to Caucasian, Non-Muslim Patients
A. Ali,¹ A. Ayub,¹ C. Richardson,¹ N. Edwards,¹ T. Ahmed,¹ M. Novak,^2,3 I. Mucsi.¹
¹Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada; ²Centre for Mental Health, University Health Network, Toronto, ON, Canada; ³Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Background:No studies have assessed whether Muslim Canadians face barriers to accessing LDKT. We explored how frequently Muslim or South Asian patients with and stage kidney…
2018 American Transplant Congress
Urological Complications of Prophylactic Ureteral Stent vs. No Stent in Kidney Transplant Recipients at Erie County Medical Center (ECMC)
M. Hamid,¹ J. Kumar,¹ S. Anjum,¹ S. Patel,² G. Gudleski,⁴ S. Mietz,³ M. Ott,³ S. Chang.¹
¹Nephrology, SUNY Buffalo, Buffalo, NY; ²Surgery, SUNY Buffalo, Buffalo, NY; ³Pharmacy, Erie County Medical Center, Buffalo, NY; ⁴Medicine, SUNY Buffalo, Buffalo, NY.
Introduction:Complications after kidney transplant (tx) commonly originate from ureterovesical anastomosis, it accounts for 3-9% of urinary complications. Due to the difference in the surgical preference,…
2018 American Transplant Congress
mTOR Inhibitor Based Immunosuppression Regimens Are Not Associated with Lower Risk for BK Infection
R. Daloul,¹ R. Pelletier,² A. Rajab,² G. Bumgardner,² M. Alebrahim,² C. Akateh,³ K. Washburn,² A. El-Hinnawi.²
¹Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH; ²Transplant Surgery, The Ohio State University Wexner Medical Center, Columbus, OH; ³Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.
Introduction: BK virus continues to be a significant post-transplant complication with increasing incidence in the current era of potent immunosuppression. Mammalian target of rapamycin inhibitors…
2018 American Transplant Congress
Development of a Classification of Immunosuppressant Medication Nonadherence Tool to Enable the Objective Measurement of Immunosuppressant Medication Nonadherence in Kidney Transplant Patients
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, London.
IntroductionKDIGO define nonadherence to immunosuppression as a 'deviation from the prescribed medication regimen sufficient to adversely influence the regimen's intended effect'. There is however, no…
2018 American Transplant Congress
Ex Vivo Bloodless Oxygen Carrier for Perfusion of DCD Kidneys during Subnormothermic Storage
P. Luke,^1,2 M. Richard-Mohamed,² A. Haig,³ R. Mayer,² S. Aquil,² A. Sener,² A. Jevnikar,^1,2 R. Bhattacharjee.^1,2
¹Matthew Mailing Centre for Translational Transplant Studies, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; ³Pathology and Laboratory Medicine, London Health Sciences Centre, London, ON, Canada.
Background: Non-oxygenated static or machine perfusion in cold (4[deg]C) remains the gold standard in transplantation and an optimal method of oxygen delivery to ischemic kidneys…
2018 American Transplant Congress
Urine Podocin mRNA to Nephrin mRNA Ratio as a Marker of "Podocyte Stress" among Kidney Allografts Losing Function
A. Naik,¹ J. Aqeel,¹ D. Cibrik,² M. Samaniego,¹ S. Wang,¹ M. Chowdhury,¹ F. Afshinnia,¹ R. Wiggins.¹
¹Univ of Michigan, Ann Arbor; ²Univ of Kansas, Kansas City.
Increasing data supports the hypothesis that long term allograft loss-of-function is associated with progressive glomerulosclerosis (GS). In models of progressive GS the ratio of two…
2018 American Transplant Congress
Assessing Fibrosis Burden in Renal Allograft with Chronic Damage Using Functional Magnetic Resonance Imaging
J. Wen,¹ W. Wang,² X. Ni,¹ Y. Yu,³ J. Chen,¹ L. Zhang,³ Z. Liu.¹
¹Jinling Hospital, Nanjing University School of Medicine, National Clinical Research Center of Kidney Diseases, Nanjing, Jiangsu, China; ²Nanjing Medical University, Jinling Clinical Hospital, Nanjing, Jiangsu, China; ³Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China.
Background: Renal allograft fibrosis burden is a strong prognosticator for chronic damage and can only be accurately measured through transplant biopsy at present. We hypothesized…