2018 American Transplant Congress
Impact of Pre-Transplant Dialysis on ESRD-Free and Patient Survival in Heart Transplant Alone and in Simultaneous Heart/Kidney Transplant Recipients: UNOS Data Analysis
Medicine, Loyola University, Maywood, IL.
It is well known that chronic kidney disease has significant negative impact on post-transplant survival in heart transplant (HTx) recipients. Here we wanted to evaluate…2018 American Transplant Congress
Screening Coccidioides Serology in Kidney Transplant Recipients: A 10-Year Cross-Sectional Analysis
1Medicine-Nephrology, UCLA, Los Angeles, CA; 2Medicine-Infectious Diseases, UCLA, Los Angeles, CA.
Introduction: Southern California is one of the endemic areas of coccidioidomycosis and patients receiving immunosuppression including kidney transplant recipients are at higher risk for dissemination…2018 American Transplant Congress
A Follow-Up Report on the Use of IVIG+Rituximab to Reduce Donor Specific Antibodies and Improve Transplant Rates in Highly-Sensitized Patients Awaiting Deceased Donor Kidney Transplantation
Medicine/Nephrology, Cedars Sinai Medical Center, Los Angeles, CA.
Introduction: Desensitization (DES) with IVIG/rituximab is associated with a reduction in donor specific antibodies (DSA), improved transplant rates and outcomes in highly-sensitized (HS) patients. We…2018 American Transplant Congress
Impact of the Differences between Body Mass Index of Recipient and Donor in a Population of Robotic Kidney Transplant
1Surgery, University of Illinois, Chicago, IL; 2Surgery, Universit of Virginia, Virginia, VA.
Introduction: The recent introduction of minimally invasive technique allows to perform kidney transplant in otherwise suitable recipients regardless the recipient BMI. This could lead to…2018 American Transplant Congress
Donor-Specific Antibody Mediates Chronic, but Not Acute, Kidney Allograft Rejection in the Absence of Natural Killer Cells
Immunology and Glickman Urological Institute, Cleveland Clinic, Cleveland, OH.
The incidence of antibody-mediated kidney graft rejection continues to increase. We previously reported that dysregulated donor-specific antibody (DSA) responses were induced in B6.CCR5-/- mice transplanted…2018 American Transplant Congress
Frailty is Predictive of Early Post-Transplant Infection in Older Renal Transplant Recipients
Background: Frailty is predictive of postoperative morbidity, including infections in older surgical patients. It is not known if frailty is associated with post-operative infections in…2018 American Transplant Congress
Diagnostic Value and Confounding Factors of Urinary Biomarkers in the Non-Invasive Screening of Renal Allograft Inflammation
IntroductionThe value of urinary biomarkers has already been demonstrated in diagnosing acute rejection of the renal allograft, but confounding factors, which may interfere with their…2018 American Transplant Congress
Efficacy and Safety of Bleselumab in Kidney Transplant Recipients: A Phase 2, Randomized, Open-Label Study
Introduction: Bleselumab (ASKP1240) is an anti-CD40 monoclonal antibody currently in development. This phase 2, randomized, open-label study assessed the efficacy and safety of bleselumab in…2018 American Transplant Congress
Relationship between Mixed Chimerism and Acceptance of HLA-Matched and Mismatched Kidney Transplants after Withdrawal of Immunosuppressive Drugs
Stanford University, Stanford, CA.
Classical studies in cattle and rodents showed that mixed chimerism (MXC) established in fetuses and neonates was permanent, linked to immune tolerance and graft acceptance…2018 American Transplant Congress
In-Situ Tissue-Based Gene Expression Profiling is a Reliable Method to Detect Gene Transcripts in Human Kidney Transplant Biopsies
Purpose. Validation studies that would enable the clinical application of quantitative in situ tissue-based gene expression profiling in renal transplantation are lacking. In this study,…
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