Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Comparison of Cephalexin and Ciprofloxacin Prophylaxis for Urinary Tract Infection in Kidney Transplant Recipients
N. A. Pauley, M. Fitzmaurice, A. Poparad-Stezar, B. Summers, A. Jantz
Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Compare efficacy and safety outcomes of patients (pts) that received alternative agents as prophylaxis (ppx) for urinary tract infection (UTI) after kidney transplant (KT)…
2022 American Transplant Congress
Role of Urinary Biomarkers in RWE Clinical Paradigm
W. Yazar¹, R. Sarwal², N. Titzler¹, M. Sarwal¹, S. Ghosh²
¹Nephrosant, Brisbane, CA, ²NephroSant, Brisbane, CA
*Purpose: Due to heterogeneity observed in the kidney transplant population, it has been extremely challenging for traditional methods such as histopathology to predict graft outcomes.…
2022 American Transplant Congress
Assessment of Humoral and Cellular Immune Responses to Sars Cov-2 Vaccination in Immunocompromised Renal Allograft Recipients
B. Shin, R. Zhang, T. M. Gadsden, A. Petrosyan, A. Vo, N. Ammerman, S. Sethi, E. Huang, A. Peng, R. Najjar, J. Atienza, I. Kim, S. C. Jordan
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: SARS CoV-2 vaccination elicits both robust humoral and T-cell immune responses in healthy individuals. However, a comprehensive assessment of immune responses to SARS-CoV-2 vaccination…
2022 American Transplant Congress
Single Port Robotic Kidney Transplantation: Comparison of Outcomes with Standard Open Kidney Transplantation
M. Eltemamy, A. Kaviani, Y. Lin, M. Abou Zeinab, V. Krishnamurthi, D. Goldfarb, J. Kaouk, A. Wee
Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH
*Purpose: To compare outcomes of the initial series of patients who underwent single port (SP) robotic kidney transplantation (KTP) with the standard open KTP.*Methods: Using…
2022 American Transplant Congress
Quantification of Center Aggressiveness in Accepting Sub-Optimal Kidney Donations from Deceased Donors in the US
T. P. Chiang¹, M. Eagleson¹, A. Massie¹, M. Krach¹, D. Segev¹, J. Garonzik Wang²
¹Department of Surgery, Johns Hopkins University, Baltimore, MD, ²School of Medicine and Public Health, University of Wisconsin, Madison, WI
*Purpose: Understanding center-level differences in usage of marginal deceased-donor kidneys (suboptimal kidneys, SOK) can help centers increase their deceased-donor transplant rate (DDKT), and to direct…
2022 American Transplant Congress
Blood Transcriptomes of Kidney Recipients with Covid-19 Demonstrate Deficient Adaptive Immune Activation
K. Banu¹, Z. Sun², Y. A. Azzi³, M. M. Rana⁴, A. Reghuvaran¹, G. Carrara⁵, S. Hartell⁴, W. Asch¹, W. Zhang⁴, Z. Zhang², E. Akalin³, P. Cravedi², P. Heeger², K. Banu¹
¹Nephrology, Yale University, New Haven, CT, ²Icahn School of Medicine at Mount Sinai, New York, NY, ³Montefiore Medical Center, New York, NY, ⁴Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, ⁵Icahn School of Medicine at Mount Sinai, New Haven, CT
*Purpose: Kidney transplant recipients (KTRs) have poor outcomes compared to non-KTRs with acute COVID-19. To provide insight into management of immunosuppression (IS) during COVID-19, we…
2022 American Transplant Congress
The Intracellular Tacrolimus Concentration in CD3⁺ T Lymphocytes and CD14⁺ Monocytes and Its Association with Kidney Transplant Rejection
S. Udomkarnjananun, C. Baan, B. de Winter, D. Hesselink
Erasmus MC, Rotterdam, Netherlands
*Purpose: The intracellular tacrolimus concentration in peripheral blood mononuclear cells (PBMCs) (TAC[PBMC]) was proposed to better represent active concentration than pre-dose whole blood concentration (C0).…
2022 American Transplant Congress
Absolute Quantification of Donor-Derived Cell-Free DNA Does Not Provide Additional Discriminating Power Over Donor-derived Cell-Free DNA Fraction for Detection of Allograft Rejection
R. Gohh¹, S. Jordan², R. N. Woodward³, K. M. Clark-Langone³, J. Morlan³, B. Silva³, M. Weir⁴
¹Alpert School of Medicine Brown University, Providence, RI, ²Cedars Sinai Medical Ctr, Los Angeles, CA, ³CareDx, Redwood City, CA, ⁴University of Maryland School of Medicine, Baltimore, MD
*Purpose: High level of background cell-free DNA (cfDNA) has been hypothesized as a concern for false negative results in molecular diagnostics for allograft rejection that…
2022 American Transplant Congress
Evaluation of Technical Bladder Complications in Kidney Transplantation Recipients with a Prolonged Dialysis History
S. M. Zielsdorf, K. Kushwaha, C. Goldbeck, S. Martin, Y. Kwon, K. Etesami, J. Kim, J. Emamaullee, S. Zielsdorf
University of Southern California, Los Angeles, CA
*Purpose: The kidney transplant (KT) waiting list continues to expand, resulting in prolonged dialysis times of >8 years prior to transplantation in some regions. The…
2022 American Transplant Congress
Bystander Suppression: Enhancing the Power of Ex Vivo Expanded Antigen Specific Regulatory Cell Lines
S. Tripathi¹, P. L. Martin-Moreno², G. J. Kavalam³, B. Schreiber³, A. Wagaa-Gasser¹, A. Chandraker⁴
¹Renal, Brigham and Women's Hospital, Boston, MA, ²Nephrology, Clinica Universidad de Navarra, Ripagaina, Spain, ³Brigham and Women's Hospital, Boston, MA, ⁴Medicine, Brigham and Women's Hospital, Boston, MA
*Purpose: The potential of T regulatory cell (Treg) based therapies in transplantation has been demonstrated in various preclinical models. Multiple clinical trials are currently undergoing…