Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Daratumumab for Treatment of Antibody-Mediated Rejection in a Kidney Transplant Recipient
S. C. Jordan¹, R. Vescio², M. Toyoda³, N. Ammerman¹, E. Huang¹, A. Peng¹, S. Sethi¹, R. Najjar¹, K. Lim¹, A. Vo¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Ctr, Los Angeles, CA, ²Cedars-Sinai Medical Ctr, Los Angeles, CA, ³Transplant Immunology Lab, Cedars-Sinai Medical Ctr, Los Angeles, CA
*Purpose: Antibody-Mediated Rejection (ABMR) is a severe form of rejection mediated by B-cells, plasma cells and antibodies. The consequences to the patients with ABMR are…
2019 American Transplant Congress
Barriers to Kidney Transplant Wait Listing among HIV Positive Patients with Advanced Kidney Disease
S. M. Boyle¹, K. Fehr¹, C. Deering², A. Raza¹, M. Harhay¹, G. Malat³, K. Ranganna¹, D. Lee¹
¹Drexel University, Philadelphia, PA, ²University of Toledo, Toledo, OH, ³Hahnemann University Hospital, Philadelphia, PA
*Purpose: Compared to HIV-negative kidney transplant (KT) candidates, the median time to waiting list activation is longer among HIV-positive candidates. Little is known about potential…
2019 American Transplant Congress
Clinical Utility of a Pharmacogenomic Testing Tool among Kidney Transplant Recipients
S. LeCorchick, L. Lindberg, W. Stapley, S. Anand, D. Morris, T. Srinivas
Kidney/Pancreas Transplant Program, Intermountain Medical Center, Murray, UT
*Purpose: Therapeutic drug monitoring (TDM) for tacrolimus (Tac) is the cornerstone of clinical workflow in the transplant clinic. We report on the clinical implementation of,…
2019 American Transplant Congress
A Pilot Study of the mDOT Platform for Immunosuppression Adherence in Adult Kidney Transplant Recipients
J. Langlee, L. Lees, A. Saha, D. Helfer, M. Waldram, A. Love, F. Rivera, A. Massie, D. Segev, D. Brennan, M. Henderson
Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: The leading predictor of rejection, de novo DSA, graft loss, and death among adult kidney transplant (KT) recipients is immunosuppressive medication nonadherence. An estimated…
2019 American Transplant Congress
Vimentin Inhibition Improves Post-Transplant Survival in a Mouse Renal Transplant Model
R. Lopez-Soler¹, Z. Zhang², H. Chin³, J. Wang⁴, K. Ridge⁵
¹Albany Medical College, Albany, NY, ²Microsurgery Core, Comprehensive Transplant Center, Northwestern University, Feinberg School of Medicine, Chicago, IL, ³Molecular and Cellular Physiology, Albany Medical College, Albany, NY, ⁴Microsurgery Core, Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Northwestern Univesity, Feinberg School of Medicine, Chicago, IL
*Purpose: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
2019 American Transplant Congress
Hope in Action: A Multicenter Prospective Study of HIV to HIV Kidney Transplantation
C. Durand¹, S. Huprikar², M. Bowring³, D. Brown¹, B. Haydel⁴, N. Desai³, F. Naqvi¹, R. Friedman-Moraco⁵, N. Turgeon⁶, V. Stosor⁷, J. Charette⁷, S. Mehta⁸, J. Husson⁹, A. Gilbert¹⁰, M. Cooper¹¹, C. Butkus-Small¹², G. Gupta¹³, S. Mehta¹⁴, O. Adebiyi¹⁵, P. Chin-Hong¹⁶, P. Stock¹⁷, A. Massie³, S. Florman⁴, D. Segev³
¹Medicine, Johns Hopkins University, Baltimore, MD, ²Medicine, Mount Sinai, New York, NY, ³Surgery, Johns Hopkins University, Baltimore, MD, ⁴Surgery, Mount Sinai, New York, NY, ⁵Medicine, Emory University, Atlanta, GA, ⁶Surgery, Emory University, Atlanta, GA, ⁷Medicine, Northwestern University, Chicago, IL, ⁸Medicine, University of Alabama, Birmingham, AL, ⁹Medicine, University of Maryland, Baltimore, MD, ¹⁰Medicine, Georgetown University, Washington DC, DC, ¹¹Department of Surgery, Georgetown University, Washington DC, DC, ¹²Medicine, Cornell University, New York, NY, ¹³Medicine, Virginia Commonwealth University, Richmond, VA, ¹⁴Medicine, New York University, New York, NY, ¹⁵Medicine, Indiana University, Indianapolis, IN, ¹⁶Medicine, University of California at San Francisco, San Francisco, CA, ¹⁷Surgery, University of California at San Francisco, San Francisco, CA
*Purpose:HIV+ donor to HIV+ recipient (HIV D+/R+) kidney transplantation (KT) has had success in South Africa. Expansion of this practice in the US setting of…
2019 American Transplant Congress
The Safety of Surveillance and Indication Biopsies in Kidney Transplantation: A Series of 2000 Biopsies
A. S. Naik¹, Y. Huang², D. M. Cibrik³, E. Shaban¹, M. McGuire¹, C. Boyer¹, S. P. Norman¹
¹Internal Medicine/Nephrology, Univ of Michigan Medical Ctr, Ann Arbor, MI, ²Internal Medicine/Nephrology, Univ of California Davis, Sacremento, CA, ³Internal Medicine/Nephrology, Kansas University Medical Center, Kansas City, KS
*Purpose: Kidney biopsy (KB) remains the most important diagnostic tool in kidney transplantation. Despite its value, surveillance KB are not routinely done at majority of…
2019 American Transplant Congress
Prevention of Ischemia Reperfusion Injury (IRI) & ABMR in HLA Sensitized Patients Treated with C1 Esterase Inhibitor (C1INH): Long-Term Follow Up
A. A. Vo, E. Huang, N. Ammerman, J. Choi, I. Kim, A. Peng, R. Najjar, S. Sethi, K. Lim, S. C. Jordan
Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: Delayed graft function (DGF) after kidney transplantation is a consequence of IRI/DGF. IRI/DGF requires intense medical management, is costly and predisposes to risk for…
2019 American Transplant Congress
Utilization of Donor Kidneys with Acute Kidney Injury in Pediatric Transplantation
C. S. Hwang¹, B. Tanriover², S. Levea², D. Desai¹, V. Ariyamuthu², P. Vagefi¹, M. MacConmara¹
¹Surgery, UT Southwestern, Dallas, TX, ²Medicine, UT Southwestern, Dallas, TX
*Purpose: Donor kidneys that are otherwise healthy with acute kidney injury (AKI) are increasingly used in adult transplant programs. We sought to examine the experience…
2019 American Transplant Congress
Factors Related to International Travel for Transplantation among US-Listed Kidney Transplant Candidates
B. Koons¹, M. L. Henderson², A. G. Thomas³, T. Kear⁴, H. Moriarty⁴
¹School of Nursing, University of Pennsylvania, Philadelphia, PA, ²Department of Surgery in the Division of Transplantation, Johns Hopkins University, Baltimore, MD, ³Department of Epidemiology, University of North Carolina, Chapel Hill, NC, ⁴M. Louise Fitzpatrick College of Nursing, Villanova University, Villanova, PA
*Purpose: The aim of this study was to identify factors associated with international travel for transplantation among US-listed kidney transplant (KT) candidates.*Methods: Using 2010-2016 data…