Articles tagged "Kidney transplantation"

2019 American Transplant Congress
Nationwide Survey of Human T Cell Leukemia Virus Type 1-Infected Kidney Transplant Recipients in Japan
J. Yamauchi¹, Y. Yamano¹, M. Matsuoka², N. Ichimaru³, M. Nishikido⁴, Y. Shibagaki⁵, A. Sugitani⁶, N. Nakamura⁷, M. Mieno⁸, K. Yuzawa⁹
¹Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kawasaki, Japan, ²Institute for Virus Research, Kyoto University, Kyoto, Japan, ³Advanced Technology for Transplantation, Osaka University, Osaka, Japan, ⁴Blood Purification Center, Nagasaki University, Nagasaki, Japan, ⁵Department of Nephrology and Hypertention, St. Marianna University School of Medicine, Kawasaki, Japan, ⁶NHO Yonago Medical Center, Yonago, Japan, ⁷Fukuoka University, Fukuoka, Japan, ⁸Center for Information, Jichi Medical University, Shimotsuke, Japan, ⁹Department of Transplantation Surgery, National Hospital Organization Mito Medical Center, Ibaraki, Japan
*Purpose: Human T-cell leukemia virus type 1 (HTLV-1) infects 5 to 10 million people worldwide, and is endemic in Japan, sub-Saharan Africa, South America, and…
2019 American Transplant Congress
Multicenter Cohort Study of Frailty and Access to Kidney Transplantation
C. Haugen¹, N. Chu¹, H. Ying¹, N. Desai¹, S. Norman², J. Garonzik-Wang¹, A. Bingaman³, D. Segev¹, M. McAdams-DeMarco¹
¹JHU, Baltimore, MD, ²MIchigan, Ann Arbor, MI, ³Methodist, San Antonio, TX
*Purpose: Frailty, a syndrome distinct from comorbidity and disability, is clinically manifested as a decreased resistance to stressors and is present in up to 35%…
2019 American Transplant Congress
Can Cardiac Risk Predictor Models Be Trusted in Kidney Transplant Recipients?
K. L. Hoffman¹, R. R. Alloway¹, A. Shields², E. Woodle², A. Govil¹
¹Nephrology & Transplant Medicine, University of Cincinnati, Cincinnati, OH, ²Transplant Surgery, University of Cincinnati, Cincinnati, OH
*Purpose: Kidney transplant recipients (KTR) bear a higher risk of developing cardiovascular disease due to comorbid conditions. Non-invasive cardiovascular risk stratification tools have not been…
2019 American Transplant Congress
Optimal Timing of Hepatitis C Treatment among HIV/HCV Co-Infected End-Stage Renal Disease Patients: Pre vs. Post-Transplant
B. Shelton¹, G. Berdahl¹, D. Sawinski², B. Linas³, P. Reese², M. Mustian¹, R. Reed¹, P. MacLennan¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ³Boston University School of Medicine, Boston, MA
*Purpose: End-stage renal disease (ESRD) patients co-infected with HCV and HIV have access to effective treatment options for HCV infection. However, they also have access…
2019 American Transplant Congress
CNI-Free Therapy with Iscalimab (anti-CD40 mAb) Preserves Allograft Histology Compared to Standard of Care after Kidney Transplantation
E. Farkash¹, A. Naik¹, H. Tedesco-Silva², B. Nashan³, O. Witzke⁴, M. van den Hoogen⁵, S. Berger⁶, D. M. Cibrik⁷, S. Mulgaonkar⁸, D. B. Leeser⁹, R. Alloway¹⁰, A. Patel¹¹, J. Pratchke¹², C. Sommerer¹³, A. Wiseman¹⁴, A. Van Zuilen¹⁵, U. Laessing¹⁶, J. Rush¹⁶, B. Haraldsson¹⁶
¹Univ of Michigan, Ann Arbor, MI, ²Hospital do Rim, São Paulo, Brazil, ³Univ. Hamburg, Hamburg, Germany, ⁴Univ Essen, Essen, Germany, ⁵Erasmus MC, Rotterdam, Netherlands, ⁶UMC Groningen, Gröningen, Netherlands, ⁷Univ of Kansas, Kansas City, KS, ⁸Saint Barnabas MC, Livingston, NJ, ⁹East Carolina Univ, Greenville, NC, ¹⁰Univ of Cincinnati, Cincinnati, OH, ¹¹Henry Ford Hosp, Detroit, MI, ¹²Charité Univ, Berlin, Germany, ¹³Univ Heidelberg, Heidelberg, Germany, ¹⁴Univ of Colorado SM, Denver, CO, ¹⁵Univ MC, Utrecht, Netherlands, ¹⁶Novartis, Basel, Switzerland
*Purpose: To assess if calcineurin (CNI)-free therapy with iscalimab preserves the quality of transplanted kidney grafts.*Methods: Iscalimab (CFZ533) is a new, fully human, Fc-silenced, non-depleting,…
2019 American Transplant Congress
Comparison of Isolated Transplant Glomerulopathy with Chronic Antibody-Mediated Rejection in Regards to Endothelial-to-Mesenchymal Transition and Graft Survival
B. H. Ozdemir¹, F. N. Ozdemir², G. Moray³, M. Haberal³
¹Pathology, Baskent University, Ankara, Turkey, ²Nephrology, Baskent University, Ankara, Turkey, ³Transplantation, Baskent University, Ankara, Turkey
*Purpose: Transplant glomerulopathy (TG) has been proposed to be a component of chronic antibody-mediated rejection (CAMR). However, a substantial number of patients with TG do…
2019 American Transplant Congress
Increase in Proinflammatory CD14++CD16+ Monocytes in Samples from Aspiration Cytology Compared with Peripheral Blood in Kidney Transplant Patients with Borderline Rejection
T. Vazquez-Sanchez¹, A. Caballero-Gonzalez², E. Sola¹, P. Ruiz-Esteban¹, E. Marques¹, J. Alonso-Titos¹, E. Palma¹, C. Jironda¹, M. Cabello¹, V. Lopez¹, P. Hidalgo¹, M. Leon¹, D. Hernandez¹
¹Nephrology, Hospital Regional Universitario de Málaga, Universidad de Málaga, IBIMA, REDinREN (RD16/0009/0006), Málaga, Spain, ²Immunology, Hospital Regional Universitario de Málaga, Universidad de Málaga, IBIMA, REDinREN (RD16/0009/0006), Málaga, Spain
*Purpose: Monocytes comprise a heterogeneous population divided according to the membrane expression level of their molecules. One of these populations is the CD14++CD16+, which presents…
2019 American Transplant Congress
Evaluation of Delayed Renal Allograft Function after DCD with New Biomarkers in Donor Blood
X. Zheng
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
*Purpose: To explore the relationship between new biomarkers in donor blood and delayed graft function (DGF) after DCD kidney transplantation, and to evaluate the clinical…
2019 American Transplant Congress
A2 To B Kidney Transplants Under Kidney Allocation System: A Prospective Study Of Anti A Titers And Correlation With Outcomes
H. Schaefer, I. Feurer, S. Rega, R. Forbes, D. Shaffer
Vanderbilt University, Nashville, TN
*Purpose: The UNOS KAS system incorporates A2 to B deceased donor kidney transplants (DDKTx) to improve access and reduce disparities in wait times for B…
2019 American Transplant Congress
Race-Sex Effects on Immune Response Potential during Tacrolimus Minimization Therapy in Stable Renal Allograft Recipients
K. Tornatore¹, K. Attwood², R. Venuto³, H. Minderman⁴
¹University at Buffalo; School of Pharmacy, Buffalo, NY, ²Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, ³University at Buffalo; School of Medicine: Nephrology, Buffalo, NY, ⁴Flow & Image Cytometry, Roswell Park Comprehensive Cancer Center, Buffalo, NY
*Purpose: African American renal transplant recipients (RTR) exhibit more immunoreactivity to allografts which may contribute to chronic rejection. This study investigated race-sex influences on ex…