2019 American Transplant Congress
Belatacept Monotherapy in Kidney Transplant Recipients with Failed Allografts Reduces Humoral Sensitization in a Single Center Randomized Controlled Trial
Emory University School of Medicine, Atlanta, GA
*Purpose: Kidney transplant recipients with failed allografts suffer from high rates of humoral sensitization. Immunosuppression (IS) strategies are highly variable in these patients with many…2019 American Transplant Congress
Elevated Donor Derived Cell Free DNA (dd-cfDNA) Levels in the Presence of Donor Specific Antibodies (DSA) Are a Strong Predictor of Antibody Mediated Rejection (ABMR) in Pediatric Renal Transplant Recipients
*Purpose: A renal biopsy, the gold standard for the diagnosis of antibody mediated rejection (ABMR) in transplant recipients, is invasive and may be associated with…2019 American Transplant Congress
Impact of Functional Delayed Graft Function in the Modern Era of Kidney Transplantation
Renal Transplant Unit, Hospital Clínic, Barcelona, Spain
*Purpose: the classical definition of Delayed Graft Function (DGF) (i.e. need of dialysis during the first week after kidney transplant) depends on the physician attitude…2019 American Transplant Congress
The Risk of Systematic Error in Kidney Transplant Opioid Research
Medical University of South Carolina, Charleston, SC
*Purpose: Opioid use before and after kidney transplant is strongly associated with morbidity and mortality; yet data assessing opioid utilization has centered on sources with…2019 American Transplant Congress
Using Transplant Referral Regions to Measure Access to Kidney Transplant
*Purpose: The transplant community has advocated to emphasize pre-transplant quality metrics to promote access to kidney transplantation (KT). Measuring access to transplant requires a well-defined,…2019 American Transplant Congress
Impact of Once-Daily Tacrolimus on Trough Concentration Variability in Stable Adolescent and Young Adult Renal Transplant Recipients
Children's Hospital Colorado, Aurora, CO
*Purpose: High tacrolimus concentration variability (Vtac), likely influenced by medication non-adherence, is a risk factor for graft dysfunction and loss among renal transplant recipients (RTRs),…2019 American Transplant Congress
Is Alemtuzumab Induction Safe In Septuagenarians Undergoing Deceased Donor Kidney Transplantation?
Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: Alemtuzumab induction in septuagenarians is controversial but understudied.*Methods: Single center retrospective review of adult deceased donor kidney transplant (KT) recipients receiving single dose (30…2019 American Transplant Congress
Racial and Ethnic Disparities in Access to Living Donor Kidney Transplantation in the US: Have We Made Any Progress among Pediatric Candidates over the Last Twenty Years?
1Johns Hopkins School of Medicine, Baltimore, MD, 2Nationwide Children’s Hospital, Columbus, OH
*Purpose: A recent JAMA study demonstrated worsening disparities in access to living donor kidney transplantation (LDKT) among adults in the US. We examined twenty-year trends…2019 American Transplant Congress
Donor-derived Cell-free Dna In Donor Specific Antibody Positive Kidney Transplant Recipients
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an emerging biomarker of kidney allograft injury. Studies examining the clinical validity of this biomarker have identified cut off…2019 American Transplant Congress
Withaferin A as a Possible Therapy for Chronic Allograft Nephropathy
*Purpose: One of the possible steps in the development of post-transplant interstitial fibrosis is epithelial to mesenchymal transition (EMT) of proximal renal tubular cells with…
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