Articles tagged "Kidney transplantation"

2022 American Transplant Congress
Progression from Kidney Transplant Referral to Initiating the Pre-Transplant Evaluation: What Causes the Break Down?
T. Menser, M. J. Hobeika, E. Hsu, L. W. Moore, A. D. Waterman, A. O. Gaber, R. J. Knight
Houston Methodist, Houston, TX
*Purpose: The transplant treatment pathway is marred by both socio-economic and racial/ethnic disparities at each stage of the process, which includes conversion from referral to…
2022 American Transplant Congress
Phenotypes of Non-Citizen Kidney Transplant Recipients in the United States by Machine Learning Consensus Clustering
P. Vaitla¹, C. Thongprayoon², C. Jadlowiec³, N. Leeaphorn⁴, S. Mao², M. Mao², A. Prakrati⁵, M. Cooper⁶, W. Cheungpasitporn²
¹University of Mississippi Medical Center, Jackson, MS, ²Mayo Clinic, Rochestor, MN, ³Mayo Clinic, Phoenix, AZ, ⁴Saint Luke, Kansas City, MO, ⁵Texas Tech, El Paso, TX, ⁶Georgetown Transplant Institute, Washington, DC
*Purpose: Health care policies and coverage for non-US citizens vary significantly across the country. Kidney transplant outcomes in non-US citizens are at par or better…
2022 American Transplant Congress
Clinically Available Immunosuppressive Agents Prolong Pig-to-Primate Kidney Xenograft Survival
I. J. Anwar¹, Q. Gao¹, I. DeLaura¹, J. Yoon¹, R. Baldi¹, M. Youd², K. Stiede², K. Hall², S. Knechtle¹, J. Kwun¹
¹Surgery, Duke Transplant Center, Durham, NC, ²eGenesis Inc, Cambridge, MA
*Purpose: Most immunosuppressive regimens used in Pig-To-Primate Xenotransplantation contain anti-CD154 agents, compounds that are currently not FDA-approved. The aim of this study was to assess…
2022 American Transplant Congress
Evaluation of a Change in Pharmacy Discharge Medication Education for Kidney Transplant Recipients
M. Borsh¹, M. Leick¹, A. Donovan², C. McAdam-Marx², M. Keck¹
¹Pharmacy, Nebraska Medicine, Omaha, NE, ²College of Pharmacy, University of Nebraska Medical Center, Omaha, NE
*Purpose: To evaluate if modification of pharmacy discharge education for kidney transplant recipients contributed to a decreased length of hospital stay (LOS) post-transplant.*Methods: This was…
2022 American Transplant Congress
Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients
A. Al Jurdi¹, R. B. Gassen¹, T. Borges¹, I. T. Lape¹, L. Morena¹, O. Efe¹, Z. Solhjou², R. El Fekih², C. Kotton¹, J. Azzi², L. Riella¹
¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA
*Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
2022 American Transplant Congress
Increased Risk for Allograft Loss in African American Kidney Transplant Recipients After Biopsy for Chronic Allograft Dysfunction
C. R. Dorr¹, B. Wu², B. Guo², W. Guan², D. Schladt¹, S. Elmer¹, G. Crary³, G. Onyeaghala¹, W. Oetting², G. Agarwal⁴, R. B. Mannon⁵, P. Jacobson², A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Medicine, University of Nebraska Medical Center, Omaha, NE
*Purpose: Chronic allograft dysfunction (CGD) is the first sign of a “troubled kidney”. CGD was defined as >25% increase in serum creatinine relative to a…
2022 American Transplant Congress
Evaluating Long Term Outcomes in Kidney Transplant Patients with TruGraf Gene Expression and TRAC Dd-cfdna in the TRULO Study
P. West-Thielke, W. Ally, J. Hickey, L. Stach, J. Fleming, T. Cober, A. Kawano, I. Agboli, C. Miller, J. Holman
Eurofins Transplant Genomics, Framingham, MA
*Purpose: The aim of this study is to evaluate long term clinical outcomes in kidney transplant patients undergoing non-invasive rejection monitoring with the OmniGraf® biomarker…
2022 American Transplant Congress
Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys
S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
2022 American Transplant Congress
Recipient Neutrophil Production of Myeloperoxidase is Required for NK Cell Activation During Acute Antibody Mediated Allograft Rejection
Y. Mitsui¹, D. Ueda¹, S. Miyairi¹, N. Dvorina¹, K. S. Keslar¹, A. Valujskikh¹, B. William¹, R. Fairchild²
¹Inflammation & Immunity, Cleveland Clinic, Cleveland, OH, ²Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Dysregulated donor-specific antibody (DSA) responses are induced in B6.CCR5-/- mice transplanted with complete MHC mismatched A/J kidney allografts and are required for rejection of…
2022 American Transplant Congress
Repeat Kidney Transplantation from Living Donors Offers Comparable Outcomes as First Transplantation
N. Oh, K. Lee, J. Rhu, J. Kim, G. Choi, J. Park, J. Joh
Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The number of patients relisted for repeat kidney transplantation is increasing due to prolonged survival after first transplantation. This study is designed to compare…