2022 American Transplant Congress
Kidney Transplantation from Deceased Donors with Vaccine-Induced Thrombosis and Thrombocytopenia: An Updated Analysis of the UK Experience
NHS Blood and Transplant, Bristol, United Kingdom
*Purpose: Vaccine-induced thrombosis and thrombocytopenia (VITT) is a rare syndrome that has emerged since widespread vaccination against SARS-CoV-2. As a result of the high mortality,…2022 American Transplant Congress
High Case Fatality Rate Among Fully Vaccinated Kidney Transplant Recipients with Breakthrough Covid-19 During the Delta Surge
Rhode Island Hospital/Brown University, Providence, RI
*Purpose: Organ transplant recipients (OTR) have worse outcomes from COVID-19 and weaker antibody responses to vaccination than do immunocompetent individuals. Data on clinical outcomes among…2022 American Transplant Congress
Autoimmune Responses to DNA Topoisomerase I Exacerbate Renal Allograft Injury
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Immune responses to self antigens develop following organ transplantation. Multiple studies describe correlations between pre-existing or de novo autoimmune responses and poor transplant outcome.…2022 American Transplant Congress
Racial Hot Spots of Non-Preemptive Kidney Transplant Wait Listing, 2010-2020
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH
*Purpose: Waitlisting kidney transplant patients before dialysis results in better long-term outcomes. Substantial racial disparities exist for preemptive waitlisting and identification of areas where race…2022 American Transplant Congress
Simultaneous Robot-Assisted Bilateral Native Nephrectomy and Kidney Transplantation for Polycystic Kidney Disease
University of Maryland, Baltimore, Baltimore, MD
*Purpose: Simultaneous bilateral native nephrectomy (NNx) and kidney transplantation is the preferred treatment for patients with end-stage renal disease (ESRD) due to symptomatic polycystic kidney…2022 American Transplant Congress
Body Composition and Relationship to Food Scarcity in Kidney Transplant Recipients (KTRS)
SUNY Downstate Health Sciences University, Brooklyn, NY
*Purpose: Pts with food scarcity often have poor dietary habits which can result in changes in body composition, including increased or decreased body fat depending…2022 American Transplant Congress
Role of CD8+T Cells Exhaustion in Long Term Spontaneous Acceptance of Mouse Kidney Allograft
*Purpose: CD8+ T cells exhaustion has been shown to promote chronic viral infection and tumor development, resulting from long term exposure to foreign antigen. We…2022 American Transplant Congress
Poor Outcomes in Patients with Transplant Glomerulopathy Independent of Banff Categorization or Therapeutic Interventions
*Purpose: Banff classification is an accepted diagnostic tool, but also used as a tool to define endpoints in clinical trials. There is a need to…2022 American Transplant Congress
Non-HLA Autoantibodies: The Hidden Offenders to Double the Trouble
*Purpose: There is emerging evidence suggesting non-HLA autoantibodies triggered after the graft injury. Here, we report 3 cases where non-HLA autoantibodies were positive after 3…2022 American Transplant Congress
Urinary Exosomal MicroRNA Biomarkers for Antibody-Mediated Rejection After Kidney Transplantation
*Purpose: We aimed to identify urine-derived exosomal miRNAs as diagnostic biomarkers for antibody-mediated rejection (ABMR) after kidney transplantation.*Methods: Exosomal miRNAs using differential ultracentrifugation were isolated…
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